DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34448 and lpl

DIOPT Version :9

Sequence 1:	NP_001097059.1	Gene:	CG34448 / 5740554	FlyBaseID:	FBgn0085477	Length:	344	Species:	Drosophila melanogaster
Sequence 2:	NP_571202.1	Gene:	lpl / 30354	ZFINID:	ZDB-GENE-990415-139	Length:	511	Species:	Danio rerio

Alignment Length:	322	Identity:	90/322 - (27%)
Similarity:	142/322 - (44%)	Gaps:	41/322 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 WLPEFCVVGEQKCPNSRVSFWLYTNQTRDDPIQLDPLNPQ--KDV-FQPRLPLKILIHGFIGN-- 86
            |:.:|..:      .|:.|| ....:..||...:.|..||  ||. |.......|:|||:...
Zfish    49 WMMDFTDI------ESKFSF-RTLEEPEDDLCYIVPGQPQSIKDCNFNTETKTFIVIHGWTVTGM 106

  Fly    87 -RNLTPNLEVRDVLLQTQP-INVISVDYGTLVRWPCYYPWAVNNAPIVSECLAQMINNLISAGIS 149
             .:..|.|..  .|.:.:| .|||.||:  |.|...:||.:.:...:|.:.:|:.:|.|.:....
Zfish   107 FESWVPKLVT--ALYEREPSANVIVVDW--LSRAQQHYPTSASYTKLVGKDVAKFVNWLQAEIDY 167

  Fly   150 RREDIHLIGFSLGAQVAGMVANYVSQPLARITGLDPAGPGFMMQPSLQQKLDASDADFVDIIHTD 214
            ..|.:||:|:||||.|||:........:.||||:|||||.|....|| ..|...||:|||::||:
Zfish   168 PWEKLHLLGYSLGAHVAGIAGLLTKHKVNRITGMDPAGPTFEYADSL-STLSPDDANFVDVLHTN 231

  Fly   215 -----PFFFSMLPPMGHADFYPNLDQLNQRGCSYISNW------------RFYNCNHYRAAVYYG 262
                 .....:..|:||.|.|||.... |.||...:..            :...|:|.|:...:.
Zfish   232 TRGSPDRSIGIQRPVGHIDIYPNGGTF-QPGCDLQNTMLMVATTGLRNMDQIVKCSHERSIHLFI 295

  Fly   263 ESIIS-ERGFWAQQCGGWFDFFSQRCSHYSNMPNTQMGYFVSE---DASGSYFLTTHEVAPF 320
            :|::: :....|.:|.....|....|.........::||.|::   ..|...::.|.|:.|:
Zfish   296 DSLVNQDHESMAFRCSSRDSFNKGMCLSCRKNRCNKVGYAVNKIRTRRSSKMYMKTREMMPY 357

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34448	NP_001097059.1	Pancreat_lipase_like	44..316	CDD:238363	85/299 (28%)
lpl	NP_571202.1	lipo_lipase	52..492	CDD:132274	89/319 (28%)
		Pancreat_lipase_like	56..353	CDD:238363	86/309 (28%)
		PLAT	360..484	CDD:294016
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11610
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.100