DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34448 and Lipc

DIOPT Version :9

Sequence 1:	NP_001097059.1	Gene:	CG34448 / 5740554	FlyBaseID:	FBgn0085477	Length:	344	Species:	Drosophila melanogaster
Sequence 2:	XP_006243421.1	Gene:	Lipc / 24538	RGDID:	3009	Length:	510	Species:	Rattus norvegicus

Alignment Length:	382	Identity:	109/382 - (28%)
Similarity:	165/382 - (43%)	Gaps:	82/382 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSIYSTLILLLTIVSGFCKGENHTRGWLPEFCVVGEQK-CPNSRVSFWLYTNQTRDDPIQLDPLN 64
            :.|..:|:|.:.|.|..|.....|..:........|:| .....:.|.|:.:::.....||.|.:
  Rat     5 LQISVSLVLCIFIQSSACGQGVGTEPFGRNLGATEERKPLQKPEIRFLLFKDESDRLGCQLRPQH 69

  Fly    65 P---QKDVFQPRLPLKILIHGFIGNRNLT-----PNLEVRDVLLQT--------------QPINV 107
            |   |:..|....||.::|||:.|:.:.|     .|....|.||:|              ||:||
  Rat    70 PETLQECGFNSSHPLVMIIHGWSGSESATVGKDSDNDSQVDGLLETWIWKIVGALKSRQSQPVNV 134

  Fly   108 ISVDYGTLVRWPCYYPWAVNNAPIVSECLAQMINNLISAGISRREDIHLIGFSLGAQVAGMVANY 172
            ..||:.:|...  :|..||.|..:|.:.:|.::..|..:....|..:||||:||||.|:|...:.
  Rat   135 GLVDWISLAYQ--HYAIAVRNTRVVGQEVAALLLWLEESMKFSRSKVHLIGYSLGAHVSGFAGSS 197

  Fly   173 V--SQPLARITGLDPAGPGFMMQPSLQQKLDASDADFVDIIHTDPFFFS---------MLPPMGH 226
            :  .:.:.||||||||||.| ...|..::|...||:|||.|||    |:         :..|:.|
  Rat   198 MGGKRKIGRITGLDPAGPMF-EGTSPNERLSPDDANFVDAIHT----FTREHMGLSVGIKQPIAH 257

  Fly   227 ADFYPNLDQLNQRGCSYISNWRF------------YNCNHYRAAVYYGESI----ISERGFWAQQ 275
            .|||||.... |.||.::..::.            ..|.|.|:...:.:|:    :...||   |
  Rat   258 YDFYPNGGSF-QPGCHFLELYKHIAEHGLNAITQTIKCAHERSVHLFIDSLQHSNLQNTGF---Q 318

  Fly   276 CGGWFDFFSQ---------RCSHYSNMPNTQMGYFVSED---ASGSYFLTTHEVAPF 320
            |.. .|.|||         ||:        .:||.:..|   .|.:.||.|...:||
  Rat   319 CSN-MDSFSQGLCLNCKKGRCN--------SLGYDIRRDRPRKSKTLFLITRAQSPF 366

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34448	NP_001097059.1	Pancreat_lipase_like	44..316	CDD:238363	98/332 (30%)
Lipc	XP_006243421.1	Lipase	18..366	CDD:278576	103/367 (28%)
		Pancreat_lipase_like	47..362	CDD:238363	98/334 (29%)
		PLAT_LPL	369..504	CDD:238856
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11610
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.100