DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34448 and Pnliprp2

DIOPT Version :9

Sequence 1:	NP_001097059.1	Gene:	CG34448 / 5740554	FlyBaseID:	FBgn0085477	Length:	344	Species:	Drosophila melanogaster
Sequence 2:	NP_035258.2	Gene:	Pnliprp2 / 18947	MGIID:	1336202	Length:	482	Species:	Mus musculus

Alignment Length:	331	Identity:	98/331 - (29%)
Similarity:	143/331 - (43%)	Gaps:	56/331 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 WLPEFCVVGEQKCPNSRVSFWLYTNQ--------TRDDPIQLDPLNPQKDVFQPRLPLKILIHGF 83
            |.||          :....|.||||:        :..||..::..|     ||.....:.:||||
Mouse    60 WSPE----------DIDTRFLLYTNENPNNYQIISATDPATINASN-----FQLDRKTRFIIHGF 109

  Fly    84 IGNRNLTPNLEVRDVLLQTQPINVISVDY--GTLVRWPCYYPWAVNNAPIVSECLAQMINNLISA 146
            |........|::...:.|.:.:|.|.||:  |:...    |..|..|..:|...:|.::..|.:.
Mouse   110 IDKGEEGWLLDMCKKMFQVEKVNCICVDWKRGSRTE----YTQASYNTRVVGAEIAFLVQVLSTE 170

  Fly   147 GISRREDIHLIGFSLGAQVAGMVANYVSQPLARITGLDPAGPGFMMQPSLQQKLDASDADFVDII 211
            .....|::||||.|||:.|||.....:...:.||||||||.|.|...|. :.:||.|||.|||:|
Mouse   171 MGYSPENVHLIGHSLGSHVAGEAGRRLEGHVGRITGLDPAEPCFQGLPE-EVRLDPSDAMFVDVI 234

  Fly   212 HTD-----PFF-FSMLPPMGHADFYPNLDQLNQRGC--SYISN-------W----RFYNCNHYRA 257
            |||     |:. |.|...:||.||:||..: ...||  :.:|.       |    .|..|||.|:
Mouse   235 HTDSAPIIPYLGFGMSQKVGHLDFFPNGGK-EMPGCQKNILSTIVDINGIWEGTRNFAACNHLRS 298

  Fly   258 AVYYGESIISERGFWAQQCGGWFDFFSQRCSHYSNMPNTQMGYFVSE------DASGSYFLTTHE 316
            ..||..||::..||....|..:..|....|.........:||::..:      ....::||.|.:
Mouse   299 YKYYASSILNPDGFLGYPCSSYEKFQHNDCFPCPEQGCPKMGHYADQFEGKTATVEQTFFLNTGD 363

  Fly   317 VAPFAK 322
            ...|.:
Mouse   364 SGNFTR 369

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34448	NP_001097059.1	Pancreat_lipase_like	44..316	CDD:238363	94/306 (31%)
Pnliprp2	NP_035258.2	Lipase	31..367	CDD:278576	97/327 (30%)
		Pancreat_lipase_like	65..363	CDD:238363	94/308 (31%)
		Required for galactolipase activity. /evidence=ECO:0000250\|UniProtKB:P54317	106..118		5/11 (45%)
		Required for galactolipase activity. /evidence=ECO:0000250\|UniProtKB:P54317	270..292		3/21 (14%)
		PLAT_PL	370..482	CDD:238857	98/331 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28N19
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11610
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000