Protein Alignment futsch and Bdp1

DIOPT Version :9

• Sequence 1: NP_001096864.1
• Gene: futsch / 5740544
• FlyBaseID: FBgn0259108
• Length: 5495
• Species: Drosophila melanogaster
• Sequence 2: NP_001074530.1
• Gene: Bdp1 / 544971
• MGIID: 1347077
• Length: 2467
• Species: Mus musculus
• Alignment Length: 3045
• Identity: 622/3045 - (20%)
• Similarity: 1062/3045 - (34%)
• Gaps: 885/3045 - (29%)

  Fly   762 KPRAEVKPVVRSRIDTKPPKSMDRKLAKRDEKKSSPTTTPAARAPVAQNAKPKVLSRPATKSS-- 824
            :.|..|||.||..:.|            |.....:|...|.|..|          ..|||:|:
Mouse     4 RARLSVKPNVRPGVGT------------RGSAAPNPQRGPEAPRP----------PEPATESAPK 46

  Fly   825 ---PSSTPAKSAKEANNRKVLESKQQAARVQATSTVSRRVTSTASERRVQQQAEAKTAATGATQA 886
               |:..||..:..|      |.::||             ..::.|:...:...|:::...:..:
Mouse    47 PAEPTDVPAVDSGGA------EPQEQA-------------PGSSDEKTGDKNNAAESSTLSSASS 92

  Fly   887 TQRKPISRRPRGVSPSKRAPAPGSPVK-------QAKPKAADLKKTRLDKGGTTDSSLVSTPSAD 944
            .:||.:|.....|.||..||:...|:.       |..|..|..|:                |.:|
Mouse    93 QRRKRVSSTSSLVQPSGSAPSQSRPLSTVDHDAPQPNPTPAKEKQ----------------PCSD 141

  Fly   945 EATAAKKLQDLTASQELDAEKQRELDDLKEEQEVVREIEAVFSRDEMKRQQHQQIKAELREMPAE 1009
            .....|            |.|.||:  ||||                .|::.:|.|.:.
Mouse   142 RYRIYK------------ARKLREM--LKEE----------------LRKEKKQWKNKF------ 170

  Fly  1010 GTGDGENEPDEEEEYLIIEKEEVEQYTED-----SIVEQES--------SMTKEEEIQKHQRDSQ 1061
            .|.:.:..||..:    :...:...|..|     |.||||.        :.|::.:..:..:|:.
Mouse   171 STNESQRPPDRSK----MTMRDFIYYLPDNNPMTSSVEQEKKPEKSLAPTPTRDRQENQSTQDAN 231

  Fly  1062 ESEKKRKKSAEEEIE---AAIAKVEAAERKARLEGASARQDESELDVEPEQSKIKAEVQDIIATA 1123
            ::|     ..|||::   ..:.:|:.|      |..|...||..|.||..::|....|::
Mouse   232 DNE-----DVEEEVDDGPLLVPRVKVA------EDGSIILDEESLTVEVLRTKGPCVVEE----- 280

  Fly  1124 KDIAKSRTEEQLAKPAEEELSSPT----PEEKLSKKTSDTKDDQIGAPVDVLPVNLQESLPEEKF 1184
                        ..|..|..|:.|    .:...||..|:.:.|.....:.:  |....|:..:.|
Mouse   281 ------------NDPIFERGSTTTYSSFRKNYYSKPWSNKETDMFFLAISM--VGTDFSMIGQLF 331

  Fly  1185 SATIESGATTAPTLPEDERIPLDQIKEDLVIEEKYVKEETKEAEAIVVATVQTLPEAAPLAID-- 1247
                          |...||.         |:.|:.:||......|..|    ..|..|...|
Mouse   332 --------------PHRARIE---------IKNKFKREEKTNGWRIDKA----FQEKRPFDFDFF 369

  Fly  1248 -----TILASATKDAPKDANAEALGELPDSGERVLPMKMTFEAQQNLLRDVIKTPDEVADLPVHE 1307
                 .:||...|...|....::|.|......:.|..|..             |.:||.|.| .|
Mouse   370 AHLLQKVLAEEEKRKQKSTKCQSLKEKASKPRKNLKAKTV-------------TSEEVNDDP-DE 420

  Fly  1308 EADLGLYEKDSQDAGAKSISHKE---------ESAKEEKETDDEKENKVGEIELGDEPNKVDISH 1363
            ..:..:.:.:.....|::::.:|         |.|..|::.:.||:.:..:    .|.||.:.::
Mouse   421 SVNSNISDPERSQNDAETVNEEESPSSSGQHLEQAMLEQDQNQEKKRRRNQ----GEANKQEATN 481

  Fly  1364 VLLKESVQEVAEKVVVIETTVEKKQEEIVEATTVITQENQEDL-MEQVKDKEEHEQKIESGII-- 1425
            :|         |:|:|..:....:    :...|..::||:.:. .||:....::...| :|:.
Mouse   482 LL---------ERVLVHSSPPAAE----IHKNTCPSEENESECNKEQIPSLTQNIDDI-AGLAPS 532

  Fly  1426 --TEKEAKKSASTPEEKETSDITSDDELPAQLADPTTVPPKSAKDREDTGSIES----------- 1477
              ||.......||..:::...:..:......:|.|...|..:|.  .|....||
Mouse   533 EETEMRMDPIPSTCNQQDIMPLARESSESCAVALPVWEPGNTAS--ADMAHAESSCSEGRGADLK 595

  Fly  1478 --PPTIEEAIEVEVQAKQEAQKPVPAPEEAIKTEKSPLASKETSRPESATGSVKEDTEQTKSKKS 1540
              .|..|:...|:.:::...|:|.|                ..:|......:|.:|.:..::|.|
Mouse   596 TAAPETEQTENVKPKSRSRLQRPKP----------------NLARAVGKKSAVSQDRQDERNKNS 644

  Fly  1541 PVPSRPESEAKDKKSPFASGEASRPESVAESVKDEAGKAESRRESIAKTHKDESSLDKAKEQESR 1605
            |..:..|....:|:        :..||.....|:..|::..     |||..|.|  :|:..|:
Mouse   645 PSETAAEKNHMEKE--------TMNESETSVAKNTDGESPG-----AKTVSDLS--EKSCVQQ-- 692

  Fly  1606 RESLAESIKPESGIDEKSALASKEASRPESVTDKSKEPSRRESIAESLKAESTKDEKSAPPSKEA 1670
             :|.|:.::|       :.|......||:....|:.|  |:|.:        |..||.....:::
Mouse   693 -DSQAKVLRP-------TRLMRSRMQRPKPNVVKAAE--RKEIL--------TSQEKFGAHVEKS 739

  Fly  1671 SRPGSVVESVKDETEKSKEPSRRESIAE-SAKPPIEFREVSRPE------SVIDGIKD------- 1721
            .....||...:.|.|..|.....::::| ..|.|.|..:..:|:      |:.:|.|:
Mouse   740 EDESCVVIPPQTENESHKNLQCEDTVSEPGRKDPFENIQPDQPQVLSDCPSIHEGNKENKRKQVP 804

  Fly  1722 ------ESAKPES-RRDSPLASKEASRPESVLES---VKDEPIKSTEKSRRESV-----AESFKA 1771
                  :..||.: ||...::|||....|:.:..   ...|.|.|.:.|.||.|     |.....
Mouse   805 VLRTRFQKPKPNTGRRRRRISSKEGIPEETPISGEIPATWEEIPSLDTSLREEVLSVPLAPLTAT 869

  Fly  1772 DSTKDEKSPLTSKDISRPESAVENVMDAVGSAERSQPESVTASRDVSRPESVAESEKDDTDKPES 1836
            .||||.:|.:  ||..|.::|        .:||.|:...||
Mouse   870 ASTKDSESDV--KDSGRNDTA--------SNAEMSEMTDVT------------------------ 900

  Fly  1837 VVESVIPASDVVEIEKGAADKEKGVFVSLE-IGKPDSPSEVISRPGPVVESVKPESRRESSTEIV 1900
                       :|:|.|           || ||:...|.|:                  .:..|.
Mouse   901 -----------MEMETG-----------LETIGRDTCPGEM------------------GAEMID 925

  Fly  1901 LPCHAEDSKEPSRPESKVECLKDESEVLK---------GSTRRESVAESDKSSQPFKETSRPESA 1956
            :|...|...:.|..|:  .|::...|::.         |.|.|:.|...:...:.....|.||:.
Mouse   926 IPMETEAGLKASLNET--SCMEKVPELIDTTGEICTNLGETGRKEVFLQENGPKEVGPVSEPETG 988

  Fly  1957 VGSM-KDESMSKE-PSRRESVKDGAAQSRETSRPASVAESAKDGADDLK---ELSRP-----EST 2011
            :... ||.:|.:. |...:|.::..|.|.||.|...::...|| |::.|   |:..|     ..|
Mouse   989 LQETGKDLAMKESTPDTTDSTEEREAYSEETERQEKISALIKD-AEEAKARGEMETPLEEIGGGT 1052

  Fly  2012 TQSKEAGSIKDEKSPLASEEASRPASVAESVKDEAE--KSKEESRRES-----------VAEKSP 2063
            :|..:|.....|:|  ||||..:.::..|.|..|:.  :.||.:.||:           :.||:.
Mouse  1053 SQRGKAAGAPVEQS--ASEEEPQGSACREEVAVESSTAEGKELNLRETGEDDVSSMVVVLGEKTD 1115

  Fly  2064 LPS-----KEASRPASVA------------ESIKDEAEKSK-EESRRESVAEKSPLPSKEASRPA 2110
            :..     ||..|.:||:            |.::|..:..| :.:.||...|:......||....
Mouse  1116 IEETNGDPKETERESSVSWERGSGEIQVGEEMVEDLGKPEKIDVAPREREPEEHSSGQPEADVIL 1180

  Fly  2111 SVAE----SIKDEAEKSKEESRRESVAEKSPLPSKEASRPASVAESIKDEAEKSKEE-------- 2163
            |.::    |.:|:...|.:.|...::.|:.....|:.|......||......:.:.:
Mouse  1181 SSSDGSTGSPQDKVNISSKISVMPTLVEEKETTDKDISSHLGHVESCSQNLGRHETDQGMPLPDA 1245

  Fly  2164 -SRRESVAEKSPLPSKEASRPASVAESIKDEAEKSKEESRRESVAEKSPLPSKEASRPASVAESI 2227
             .|........|||.::.......|..::...:|.|....|  .|.|......|...|...:|:.
Mouse  1246 LERFSDTNLSKPLPQEQQPLQVKPAPFLRSRFKKPKPNLSR--AALKRATIEAEHCVPGKKSEAC 1308

  Fly  2228 KDEAEKSKEESRRESVAEKSPLPSKEASRPASVAESIKDEAEKSKEESRRESVAEKSPLPSKEAS 2292
            |.||...:::|.:.:::.:..:||..|||          |.:||..|...|:.........|:||
Mouse  1309 KVEAAMLQQDSDQAALSPQHNVPSLMASR----------ENDKSGHEEEEEAAILPCTQTEKDAS 1363

  Fly  2293 RPASVAESIKDEAEKSKE-----------------ETRRESVAE--------KSPLPSKEASRPA 2332
            .|.|.......:...::|                 |||:..|..        :.|.|:.:.:|..
Mouse  1364 PPNSSEPKEGSQLTPNQENGLLVPIGTPMMNTVTQETRQNVVQTTLPVRGRLQRPRPNVQKARQR 1428

  Fly  2333 SVAESIKDEAEKSKEESRRESAAEKSPLPSKEASRPA-SVAESVKDEADKSKEESRRESMAESGK 2396
            .:.|  |.||        |:.|..:.|...|:.:|.. :||.|...|:..:.:.|.|.|..:..:
Mouse  1429 QIVE--KGEA--------RDIAKNEGPELQKDETRTCLTVANSSHIESGVAVDMSSRVSECQVSE 1483

  Fly  2397 AQSIKGDQSPLK--EVSRPESVAESVKDDPVKSKEPS------RRESVAGSVTADSARDDQSPLE 2453
            :|   |...|::  .|::...|.|.::.:. |...||      ||...|......:.|.|:.|..
Mouse  1484 SQ---GHADPVENLSVNKASVVHEQMRHEN-KPYVPSPALLIRRRFQKAKPNLGGARRKDEQPGV 1544

  Fly  2454 SKGASRPESVVDSVKDEAEKQESRRESKTESVIPPKAKDDKSPKEVLQPVSMTETIREDADQPMK 2518
            .||.: .||...:.:|...:                 |:|...:..||       .||.||.|::
Mouse  1545 EKGRT-DESTALTAEDHLLQ-----------------KEDCDTQLSLQ-------AREKADMPLE 1584

  Fly  2519 PSQAESRRESIAESIKASSPRDEKSPLAS-KEASRPGSVAES-IKYDLDKPQIIKDDKST-EHSR 2580
            .|   .|:|.| .|.::.|.|::..|.|. .|.||..:..|. ....|::..:.|..:|: ....
Mouse  1585 VS---VRKECI-HSEESGSDRNDAQPNAGPSEGSRDETAKEQPTSLGLEEQSLSKQIRSSCPQLW 1645

  Fly  2581 RESLEDKSAVTSEKSVSRPLSVASDHEAAVAIEDDAKSSISPKDKSRPGFVAETVSSPIEEATME 2645
            :||...|: |:|.::   |||.||:.|    ||...|.:   :.|::|.......|..|...|
Mouse  1646 KESSYPKT-VSSRRT---PLSSASECE----IEHSWKRT---QRKTKPNLTKGRGSKRIRGKT-- 1697

  Fly  2646 FSKIEVVEKSSLALSLQGGSGGKLQTDSSPVDVAEGDFSHAVASVSTVTPTLTKPAELAQIGAAK 2710
             :|.|.....|:.::|:...    :.|....:..:.|:......:
Mouse  1698 -AKKEPRASKSVLVTLRASQ----KEDEDDAEDFDSDYEEETYHL-------------------- 1737

  Fly  2711 TVSSPLDEALRTPSAPEHISRADSPAECASEEIASQDKSPQVLKESSRPAWVAESKDDAAQLKSS 2775
                          |||.:|                 |:|..:     |..:...:..:||::.:
Mouse  1738 --------------APEELS-----------------KAPVFV-----PVGLRSPEPVSAQIEET 1766

  Fly  2776 VEDLR--SPVAS-TEISRPASAGETASSPIEEAPKDFAEFEQAEKAVLPLTIELKGNLPTLSSPV 2837
            :|:|.  ..||. |.:....|..:|.:..:           ||||||.|.:.|:
Mouse  1767 MEELEITMDVADMTVVEHQLSHMDTTAQAV-----------QAEKAVYPPSFEM----------- 1809

  Fly  2838 DVAHGDFPQTSTPTSSPTVASVQPAELSKVDIEKTASSPIDEAPKSLIGCPAEERPESPAESAKD 2902
            ||.                             |:|...|                  .|::.:.:
Mouse  1810 DVG-----------------------------EQTQEEP------------------GPSDGSTE 1827

  Fly  2903 AAESVEKSKDASRPPSVVESTKADSTKGDISPSPESVLEGPKD-------DV---EKSKESSRPP 2957
            ||.::                   .|.|||....| ::.|..|       ||   :||.....|.
Mouse  1828 AAITL-------------------LTMGDIVLQSE-IIPGQGDVGVCVFPDVHSEDKSHAPFSPD 1872

  Fly  2958 SVSASITGDSTKDVSRPASVVESVKDEH---DKAESRRESIAKVESVIDEAGKSDSKSSSQDSQK 3019
            :|:..:..|..:..|...|...:..:|:   .|.:|.|::..:.|:|             :::..
Mouse  1873 NVNQKVVHDYPEVCSPVISTSHASFEENRIVSKEQSNRDAAVEEEAV-------------EETLP 1924

  Fly  3020 DEKSTLASKEASRRESVVESSKDDAEK----SESRPESVIAS-------GEPVPRESKSPLDSKD 3073
            ...:|.......|.||:|.:.:.::||    |||.....:||       ...:.||::.. |||.
Mouse  1925 TRNTTSTMSTHLRMESMVVTPELNSEKTLEISESHGHQEVASFCITKETEVEIQRETEGD-DSKA 1988

  Fly  3074 TSRPGSMVESVTAEDEKSEQQSRRESVAESVKADTKKDGKSQEASRPSSVDELLKDDDEKQESRR 3138
            ..........|||.:.|.|:||:       ...|.:....||||..|:.:::..:...|.|||
Mouse  1989 VELEDKSHAPVTAAETKEEEQSQ-------CVGDVEGASVSQEAILPARIEDHEETLQEVQES-- 2044

  Fly  3139 QSITGSHKAMSTMGDESPMDKADKSKEPSRPESVAESIKHENTKDEESPLGSRRDSVAESIKSDI 3203
                |:..|.|.:|.:: :|......|.:..|::.|:.|..:......|         ||:.|.|
Mouse  2045 ----GTAVASSEIGQQT-LDSGQSFGESAAKEALKETPKGSDVPVLHGP---------ESVPSHI 2095

  Fly  3204 TKGEKSPLPSKEVSRPESV-VGSIKDEKAESRRESVAESVKPESSKDATSA-PPSKEHSRPESVL 3266
                  |...:|.:.|::| |....|.:.:...|........|....||.. ..:.....|.|:|
Mouse  2096 ------PEAQQENTGPQAVTVNPFADGQQDGEDEQAFILTLVEIPTHATEGFTDAAMQLMPSSLL 2154

  Fly  3267 --------GSLKDEGDKTTSRRVSVADSIKDEKSLLVSQEASRPESEA---------------ES 3308
                    |:..:.||.:.|.:.|:.  ::|..||..|:..|..:..|               ||
Mouse  2155 PAPILVRSGNAAERGDLSGSLQTSLV--VQDAPSLSPSRSGSSEKPPANLDLTSRKRFCCSPDES 2217

  Fly  3309 L------KDAAAP------------SQETSRPESVTES-VKDGKSPVA---------SKEASRPA 3345
            :      |.:..|            |:|.:..|...|| :..|..|.:         .||.|.|.
Mouse  2218 IHVPPAKKSSLVPGIDYQECTSEVCSEELNVFEKTAESCMGQGIFPTSESTHATSKPQKEHSEPT 2282

  Fly  3346 SVAENAKDSADESKEQRPES---LPQSKAGSIKDEKSPLASKDEAEKSKEESRRESVAE--QFPL 3405
            ....:.  |.||.|:...|:   ||||:..|.|:||:..||..|.......|.:..:..  :.||
Mouse  2283 DTGSSG--SLDEIKDACVENMAQLPQSEIVSDKEEKTEPASNSEQRDIVTSSSKPPLTRPGRRPL 2345

  Fly  3406 VSKEVSRPASVAESVKDEA------EKSKEESPLMSKEASRPASVAGSVKDEAEKSKEESRR--E 3462
            ....:..|.:..||  ||.      ::.|.:.|:..:...:|     ::.:.::|..::|..  .
Mouse  2346 GFLSLLCPKNSLES--DEVTQTHSKKRLKPQIPVSRRNLRKP-----NLHNTSQKKNQDSSAPPP 2403

  Fly  3463 SVAEKSPLPSKEASRPASVAESVKDEADKSKEESRRESGAEKSPLASKEASRPAS 3517
            |.:..:|| |..|..|.|.|..|..:....|||.:  :|.:.:|   :|...|.|
Mouse  2404 SPSVTAPL-SGTAGSPESSAAQVSSDQPLLKEECK--NGPKGAP---EEEVTPVS 2452

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
futsch	NP_001096864.1	DUF966	<1925..>2112	CDD:283735	55/236 (23%)
Bdp1	NP_001074530.1	Interaction with ZBTB43. /evidence=ECO:0000250	1..301		83/421 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..145		40/197 (20%)
		BDP1	<93..416	CDD:227448	88/448 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	159..243		19/98 (19%)
		Myb_DNA-bind_7	299..382	CDD:292585	21/111 (19%)
		Required for phosphorylation by CSNK2A1. /evidence=ECO:0000250	357..472		25/136 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	380..513		29/163 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	576..720		35/186 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	748..844		19/95 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	866..893		10/36 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	971..1200		54/231 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1231..1270		4/38 (11%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1318..1388		17/79 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1409..1448		10/48 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1527..1561		9/34 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1592..1706		34/128 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1902..1926		5/36 (14%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1977..2014		12/44 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	2058..2083		5/24 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	2179..2206		6/28 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	2260..2290		6/31 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	2304..2449		39/157 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000