Protein Alignment futsch and Phf3

DIOPT Version :9

• Sequence 1: NP_001096864.1
• Gene: futsch / 5740544
• FlyBaseID: FBgn0259108
• Length: 5495
• Species: Drosophila melanogaster
• Sequence 2: NP_001102261.1
• Gene: Phf3 / 363210
• RGDID: 1304925
• Length: 2020
• Species: Rattus norvegicus
• Alignment Length: 2395
• Identity: 473/2395 - (19%)
• Similarity: 812/2395 - (33%)
• Gaps: 749/2395 - (31%)

  Fly  1395 TTVITQENQEDLMEQVKDKEEHEQKIESGIITEKEAKKSASTPEEKETSDITSDDELPAQLADPT 1459
            |||:   ..:|:|::             |::              ||:.:.|.|:|       ..
  Rat    80 TTVV---GLDDIMDE-------------GVV--------------KESGNDTIDEE-------EL 107

  Fly  1460 TVPPKSAKDREDTGSIESPPTIEEAIEVEVQAKQEAQKPVPAPEEAIKTEKSPLASKE------- 1517
            .:|.:|.:||.:..|:.||......:..| |.:...|..:     |.::..:||::|:
  Rat   108 ILPNRSLRDRVEDNSVRSPRKSPRLMAQE-QVRSLRQSTI-----AKRSNAAPLSTKKPSGKTFS 166

  Fly  1518 TSR-----PESATGSVKEDTEQTKSKKSPVPSRPES------------EAKDKKSPFAS------ 1559
            ||:     ||...|  ||:...:...:.|..||..|            .|....||..|
  Rat   167 TSKAGVKPPERCQG--KEEVYASLKSEHPKESRRNSRHAEHMDMVLEVSASSADSPVPSCVGMKE 229

  Fly  1560 -------------GEASRPE-----SVAESVKDEAGKAESRRESIAKTHKDESSLDKAKEQESRR 1606
                         ||.|.|.     |........||....|.|::.:.....|.|.|...:|
  Rat   230 AAELHPRHACNNQGEVSAPSPDLSCSPPSEASASAGVGGKRTEALMECKTSSSPLFKVSVKE--- 291

  Fly  1607 ESLAESIKPESGIDEKSALASKEASRPESVTDKSKEPSRRESIAESLKAESTKDEKSA-PPSKEA 1670
                         ||:|.|.|.|.   :...:......|.|..:|.:|.....|..|. |.|.:.
  Rat   292 -------------DEQSDLVSGEL---DDTIEGVNAVGRLEQESEEIKFSCEGDRMSTEPESSDV 340

  Fly  1671 SRPGSVVESVKDETEKSKEPSRRESIAESAKPPIEFREVSRPESVIDGIKDESAKPESR------ 1729
            |...:..:  |::|||:          |.|:..:|.:..   ..::|  |.|::.|.::
  Rat   341 SSDSACTD--KNKTEKN----------EGAQCHLELKNT---VDIVD--KPENSPPSNQMEMLDY 388

  Fly  1730 ------RDSPLASKEASRPESVLESVKD---EPIKST----------EKSRRESVAESFKADST- 1774
                  .|:.|.|.|.::  |.||.|..   ||..||          :.|::.::.:|.|.:::
  Rat   389 GEDVGTNDAQLQSTEFTK--SHLEEVDTCAFEPETSTFENTICDVPDQNSKQLNITQSIKMETSN 451

  Fly  1775 -KDEKSPLTSKDI----------SRPESAVENVMDAVGSAERSQPESVTASRDV--SRPESVAES 1826
             :|::|.|..|::          |:|...:|           :..::|....:|  |:.:|.|::
  Rat   452 LQDDRSGLGPKNMKSKHTKSVTHSKPSMTIE-----------TPRKTVAVKPEVGHSKTKSNAKT 505

  Fly  1827 EKDDTDKPESVVESVIPASDVVEIEKGAADKE-------------KG-VFVSLEIGKPDSPSEVI 1877
            .|.:.|:||...:...|    |::.|...||:             || |...|:....|..:..|
  Rat   506 MKRNADEPEPQPDCQRP----VKVRKKQVDKDLKSQSCNSGVKSVKGQVHSVLKKIPQDQTAMQI 566

  Fly  1878 SRPGPVVESVKPESRRESSTEIVLPCHA--------EDSKEPSRPESKVECLKDESEVLKGSTRR 1934
            |:  |:..||..:....|...:..|.|.        .:.|:..:|:.:...::..|.|
  Rat   567 SK--PLTHSVNDKLPGHSGHSLEKPPHPGHTGHLVHSNQKQSHKPQPQAGAVRVTSHV------- 622

  Fly  1935 ESVAESDKSSQPFKETSRPESAVGSMKDESMSK--EPSRRESVKDGAAQSRETSRPASVAESAKD 1997
                 .|:...|..|..:.|.   .:|.:.:.:  :|.:|.|.:..:........|.::|...|:
  Rat   623 -----RDEHEHPGTEHPKEED---KLKPKKLDRNLQPRQRRSSRSFSLDEPPLFIPDNIATVKKE 679

  Fly  1998 GADDLKELSRPESTTQSKEAGSIKDEKSPLASEEASR------------PASVAESVKDEAEK-- 2048
            |:|....:......|.||:.|..|............|            ..|.|:.:.:|.::
  Rat   680 GSDQTTSVENKYMWTPSKQCGFCKKPHGNRFMVGCGRCDDWFHGDCVGLSLSQAQQMGEEDKEYV 744

  Fly  2049 ----SKEESRRESVAEKSPLPSKEASRPASVAESIKDEAEKSKEESRRESVAEKSPLPSKEASRP 2109
                ..||.::..:.:...|.: :||..|. :|..:.|..|....|.:.||.|.......:..|
  Rat   745 CIRCCAEEDKKTDILDTETLET-QASLEAH-SEDKRVECGKLTSSSSKHSVTEDKHRHMDDPGR- 806

  Fly  2110 ASVAESIKDEAE-KSKEESRRESVAEKSPLPSKEASRPASVAESIKDEAEKSKEESRRESVAEKS 2173
            ..|....:|..| |:..:||...:.:....|.::..:|.....|.::::||..::|...:.|
  Rat   807 HKVKIVKRDSGEGKTSSDSRDNEIKKWQLAPLRKLGQPLLPRRSSEEKSEKIAKDSAALTCA--- 868

  Fly  2174 PLPSKEASRPASVAESIKDEAEKSKEESRRESVAEKSPLPSKEASRPASVAESIKDEAEKSKEES 2238
               .::|:|..:          ..|:|::::.|.:..|    ....||:.|  ||..|::.::
  Rat   869 ---GEKAARSGT----------HEKQETKKKKVEKGGP----NVHPPAAAA--IKPSADQIRQ-- 912

  Fly  2239 RRESVAEKSPLPSKEASRPASVAESIKDEAEKSKEESRRESVAEKSPLPSKEASRPASVAESIKD 2303
                                ||..|:||...|...:|..:...|||          |.||..|:.
  Rat   913 --------------------SVRHSLKDILMKRLTDSNLKIPEEKS----------AKVATKIEK 947

  Fly  2304 EAEKSKEETRRESVAEKSPLPSKEASRPASVAESIKDEAEK------SKEESRRESAAEKSP--L 2360
            |......:|           .:|..::..|:..::||....      .|.|...:.....||  |
  Rat   948 ELFSFFRDT-----------DAKYKNKYRSLMFNLKDPKNNILFKKVLKGEVTPDHLIRMSPEEL 1001

  Fly  2361 PSKEASRPASVAESVKDEADKSKEESRRESMAESGKAQSIKGDQSPLKEVSRPESVAESVKDDPV 2425
            .|||.:            |.:.:|......|.|..:.:.   ::.|:.:::....: |...|.|:
  Rat  1002 ASKELA------------AWRRRENRHTIEMIEKEQREV---ERRPITKITHKGEI-EIESDAPM 1050

  Fly  2426 KSKEPSRRESVAGSVTADSARDDQSPLE-SKGASRPESVVDSVKDEAEKQESRRESKTES----- 2484
            |.:|              :|.:.|.|.. :|.:.:||:      .|.:|:|....||..:
  Rat  1051 KEQE--------------AAMEIQEPSSANKSSEKPEA------SEKQKEELDSTSKDTTSQHRQ 1095

  Fly  2485 -------------VIPPKAKDDKSPKEVLQPVSMTETIREDADQPMKPSQAESRRESIA------ 2530
                         :.||  .||.|||.|...|.   ..|:.:|     ::|||..::::
  Rat  1096 HLFDLNCKICIGRMAPP--VDDLSPKTVKVVVG---GARKHSD-----NEAESIADALSSTTNIL 1150

  Fly  2531 -----ESIKASSPRDEKSPLASKEASRPGSV-AESI---------KYDLDKPQIIKDDKSTEHSR 2580
                 |..|..||:...||....|  .||:| .||.         |..::.|.:.|
  Rat  1151 ASEFFEEEKQESPKSTFSPTPRPE--MPGTVEVESTFLARLNFIWKGFINMPSVAK--------- 1204

  Fly  2581 RESLEDKSAVTSEKSVSRPLSVASDHEAAVAIEDDAKSSISPKDKSRPGFVAETVSSPIEEATME 2645
                    .||.    :.|:|.:.::     :.:|...||....:..|..|.:.|.......|.|
  Rat  1205 --------FVTK----AYPVSGSPEY-----LTEDLPDSIQVGGRISPQTVWDYVEKIKASGTKE 1252

  Fly  2646 FSKIE---VVEKSSLALSLQGGSGGKLQTDSSPVDVAEGDFSHAVA----SVSTVTPTLTKPAEL 2703
            ...:.   |.|:..::.:|.                    |::..:    .|:.......|...|
  Rat  1253 ICVVRFTPVTEEDQISYTLL--------------------FAYFSSRKRYGVAANNMKQVKDMYL 1297

  Fly  2704 AQIGAAKTVSSPL------DEALRTPS------APEHISRADSPAECASEEIASQDKSPQVLKES 2756
            ..:|||..:..||      ...|..|:      ..:.:.|..| |.......|...:|..:....
  Rat  1298 IPLGAADKIPHPLVPFDGPGLELHRPNLLLGLIIRQKLKRQHS-ASAGPSHTAETPESAPISLPP 1361

  Fly  2757 SRPAWVAESKDDAAQLKSSVEDLRSPVASTEISRPASAGE----TASSPIEEAPKDFAEFEQAEK 2817
            .:...:..|.::||:.:|...:..:.|...:.::|....:    ||:.|:.|..|     ::..|
  Rat  1362 DKKGKMESSTEEAAEEESDFFNSFTTVLHKQRNKPPQPPQEDLPTAAEPLMEVTK-----QEPPK 1421

  Fly  2818 ------AVL------PLTIELKGNLPTLSSPVDVAHGDFPQTSTPTSSPTVASVQP----AELSK 2866
                  .||      |.|:|| .|.|.   |||    |..|:...|:.......||    :.|.:
  Rat  1422 PLRFLPGVLIGWENQPSTLEL-ANKPL---PVD----DILQSLLGTTGQVYEQAQPVVEQSTLKE 1478

  Fly  2867 VDIEKTASSP----IDEAPKSLIGCPAEERPESPAESAKDAAESVEKSKDASRPPSVVESTKADS 2927
            :......::|    ||:.          |..|..|:..|..||:|.:|...:   |.||.|....
  Rat  1479 IPFINDQTTPKVEKIDKV----------EVTEGEAKEIKVKAENVSESTGKN---SGVEETSLVG 1530

  Fly  2928 TKGDISPSPESVLEGPKDDVEKSKESSRPPSVS--ASITGDSTKDVSRPASVVESVKDEHDKAES 2990
            : ..|||.|.:.|          ....:||.||  |.:|     ::|.|:...|:|:::
  Rat  1531 S-SSISPGPLASL----------SLRGKPPDVSTEAFLT-----NLSIPSKQEETVENK------ 1573

  Fly  2991 RRESIAKVESVIDEAGKSDSKSSSQDSQKDEKS-------------TLASKE------------- 3029
                    |..:......|.::||||::....|             .::..|
  Rat  1574 --------ERTLKRPLLQDQENSSQDNRTCSNSPCRPSTGKGSVDGNVSCSENLVANTRSPQFIN 1630

  Fly  3030 --------ASRRESVVESSKDDAEKSESRPESVIASG------EPVPRESKSPLDSKDTSRPGSM 3080
                    |.|.:..|..|||..........||.|..      |||..|.|          |.|:
  Rat  1631 LKRDPRQAAGRSQQTVSDSKDGESCRNGERHSVCAPSYNREPVEPVSGEGK----------PSSL 1685

  Fly  3081 VESVTAEDEKS---EQQSRRESVAESVKADTKKDGKSQEASRPSSVDELLKDDDEKQESRRQSIT 3142
                    |||   ||....|:|..|...:.....::::|: |...|.|.::.:.....||.|.|
  Rat  1686 --------EKSSCVEQSDDSEAVPNSSSVENSNSSQAEQAN-PLQEDILTQNIETIHPFRRGSAT 1741

  Fly  3143 GS--HKAMSTMGDESP-----------MDKADKSKEPSRPESVAESIKHENTKDEESPLGSRRDS 3194
            .|  .:..:|...|.|           ..:|..:..|.||:.  .:::|.    :.||.|
  Rat  1742 SSSHFEGGNTCQSEFPSKSINFTPRSTSPRASTNFSPMRPQQ--PNLQHL----KSSPPG----- 1795

  Fly  3195 VAESIKSDITKGEKSPLPSKEVSRPESVVGSIKDEKAESRRESVAESVKP----------ESSKD 3249
                          .|.|..:...|:||.|             ....:.|          ..:..
  Rat  1796 --------------FPFPGPQNFPPQSVFG-------------FPPHLPPPLLPPPGFGFPQNPP 1833

  Fly  3250 ATSAPPSKEHSRPESVLGSLKDEGDKTTSRRVSVADSIKDEKSLLVSQEASRPE---SEAESLKD 3311
            ....||.....:|:.::|.|            |.|......::....::..|||   |:....:|
  Rat  1834 MAPWPPVHVPGQPQRMMGPL------------SQASRYMGPQNFYQVKDIRRPERRHSDPWGRQD 1886

  Fly  3312 AAAPSQETSRPESVTESVKDGKSPVASKEASRPASVAENAK-DSADESKEQRPESLPQSKAGSIK 3375
            ...|.:..:|          ||.     :..|..|.:.:.| |..|:..||      :|:....:
  Rat  1887 QQQPDRPFNR----------GKG-----DRQRFYSDSHHLKRDRHDKEWEQ------ESERHRHR 1930

  Fly  3376 DEKSPLASKDEAEKSKEESRRESVAEQFPLVSKEVSRPASVAESVKDEAEKSKEESPLMSKEASR 3440
            |...   .||...|||||:.            |:..|| .::.|.:....|:..||....|:..|
  Rat  1931 DRSQ---EKDRDRKSKEEAH------------KDKERP-RLSHSDRAADGKANRESKSADKKPDR 1979

  Fly  3441 PASVAGSVKDEAEKSKEESRRESVAEKSPLPSKEASRPASVAESVKDEADKSKEE 3495
            |..      ::.||.||.       |||  ..:|..:........:|..|::|.:
  Rat  1980 PKG------EDHEKEKER-------EKS--KHREGEKDRERYHKDRDHTDRAKSK 2019

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
futsch	NP_001096864.1	DUF966	<1925..>2112	CDD:283735	38/206 (18%)
Phf3	NP_001102261.1	PHD_PHF3	698..748	CDD:277108	6/49 (12%)
		TFIIS_M	908..1018	CDD:284835	30/164 (18%)
		SPOC	1193..1299	CDD:285043	22/151 (15%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000