Protein Alignment futsch and map1a

DIOPT Version :9

• Sequence 1: NP_001096864.1
• Gene: futsch / 5740544
• FlyBaseID: FBgn0259108
• Length: 5495
• Species: Drosophila melanogaster
• Sequence 2: XP_004912694.3
• Gene: map1a / 100493436
• XenbaseID: XB-GENE-999071
• Length: 3138
• Species: Xenopus tropicalis
• Alignment Length: 3593
• Identity: 778/3593 - (21%)
• Similarity: 1323/3593 - (36%)
• Gaps: 964/3593 - (26%)

  Fly   119 LLIVLGEPHSEEHKDNILQHLLKGFLSWDVS--DCHVDLEEELNTITQHAPEGEEARHGERLIQY 181
            ||||:|:..:|.....:..||.:|..||::|  .|.::.:.:|..|...|....:.: |:|.:|:
 Frog    31 LLIVIGDVSTESQLQAVRDHLERGIRSWNISLDSCDLNYQLKLFAIRHLAHFSPDVK-GQRTLQH 94

  Fly   182 ASENLVTEVLIHPQYNTLIQCMRNLLSSFTRHRHIIHAGYTFSGNGSWILQDGTFSVADFSEAFQ 246
            .|:.|.|.||::|..::::|.:|:|::..:.|:..|.:|.:....|..|||..||:...|.|.|.
 Frog    95 RSDVLETVVLVNPNADSIVQEVRSLITGSSAHKLFILSGQSSEQEGDLILQTETFTYQRFEEVFS 159

  Fly   247 EHDV-QRVIRAYADT-ITMNIHCADAGLWHTLPEKAFARQCRIRINPVDVLDTSSECINGFIDYL 309
            :.:| |::.....:| .::.:.|...|.|..:....|.....|::|| |:.....:.|:.|.||:
 Frog   160 DPEVCQQLSNTDPETKASLTVSCLGEGDWCNIGSSGFQDIIHIKLNP-DLALPEMDGISEFADYV 223

  Fly   310 APMVMPTSLRELLETSDVVGNIRFTHPTLYVFPGGQGDAALFGINGFNMLVDGGFNRKACFWDFA 374
            :..|...|..:|||..:..|.::.:.|..|:||||:||:|||.:||||:|||||..||:|||...
 Frog   224 SETVDVPSPFDLLEPPNSGGFLKLSKPCCYIFPGGRGDSALFAVNGFNILVDGGSERKSCFWKLV 288

  Fly   375 RHLDRLDAVLMTRLNNSNVQGLGAVVSRK---RDAH---------------VYPQIGHFFGNVPD 421
            |||||:|::|:|.:...|:.|:..::.||   :|..               :.|::|..|.||||
 Frog   289 RHLDRIDSILLTHIGADNLPGINGLLQRKIAEQDEEQSQGSTTYSDWMKNLISPELGVVFFNVPD 353

  Fly   422 RKGLPSPDGDKDRDPLLIDLFERGHGIVSDLKALDLKPQCCYR----NQEPVNLYHKVGHGTLDM 482
            :..:|..:....|.      .|.....:..|..|.:||:..||    ..||:.|:||:|.|.|||
 Frog   354 KLKMPESNMKVKRS------IEEACLTLQYLNKLGIKPEPLYRVVSNTIEPITLFHKMGVGRLDM 412

  Fly   483 YVISPARDSKEVKEFLQKWHAGDQR-----LFAARDSRDFNFPLQNLVSICALLVWQPANPDDTI 542
            |:::|.:||||::..:||| ||:.:     :.|.....:.:.|.  |.||.||:||.||:|.:.|
 Frog   413 YILNPVKDSKEMQFLMQKW-AGNSKAKTGIILANGKEGEISVPY--LTSITALVVWLPASPTEKI 474

  Fly   543 TRILFPGSTPDFKIQEGLEKLKHLEFMKHSTCTAKSIAPAIQTVT-----STRKSLKSAIEATPA 602
            .|:||||:.|..||.|||||||||:|:::...|.|.|:..|.|.|     ..|...|.::::||.
 Frog   475 VRVLFPGNAPQNKILEGLEKLKHLDFLRYPVATQKDISAGIPTTTKHTKIKQRVDSKESLKSTPR 539

  Fly   603 PPSASYKTTKFSPVASAALAVQHPQQQDNKAKEAAAAAAAAAAAAASAATIARAKADSMDTDAEP 667
            |.:.                      :.||.:|.|
 Frog   540 PSTG----------------------KPNKREEIA------------------------------ 552

  Fly   668 EHEADPEPADTGDEAAPTEQ-EPEAETEPEPEHEPEAEQDKDVGEEKKVEVL-IMKPQQATPAVI 730
                              || ..|.:|||..|...|.:..||..::...:|| ..|.:..|...:
 Frog   553 ------------------EQLTKEIKTEPAKETRLEKKTLKDSTDKSTEKVLKFEKVKTETSESV 599

  Fly   731 AASGKDGVDAASADATPTGKLSKASAKGKADKPRAEVKPVVRSRIDTKPP--KSMDRKLAKRDEK 793
            .|..:..:...:.......|:||  .:.|.||.:.|::   :.:.|.|..  |..|:|..|::||
 Frog   600 KAEKRKLLKEKTGKKYTKDKMSK--LEEKKDKEKKEIR---KEKTDLKKDILKKEDKKDTKKEEK 659

  Fly   794 KSSPTTTPAARAPVAQNAKPKVLSRPATKSSPSSTPAKSAKEANNRKVLESKQQAARVQATSTVS 858
            |..      .:..|.:..||.:  ||.|...              ||.|.
 Frog   660 KKE------LKPDVKKMMKPDL--RPFTPEV--------------RKTLH--------------- 687

  Fly   859 RRVTSTASERRVQQQAEAKTAATGATQATQRKPISRRPRGVSPSKRAPAPGSPVKQAKPKAADLK 923
                            :||..:.|.|:..:.||                      :.:...|:.|
 Frog   688 ----------------KAKLPSKGKTEKIKSKP----------------------EKETITAEQK 714

  Fly   924 KTRLDKGGTTDSSLVSTPSADEATAAKKLQDLTASQELDAEKQRELDDLKEEQEVVREIEAVFSR 988
            .::|.:   .......|..|::.:|....:|||.    |.|:.:..|.|  ||....:.:...|:
 Frog   715 TSQLQQ---IQKQQQLTHMAEQRSAMSSPEDLTK----DFEELKYEDKL--EQIQYEDDDKNISK 770

  Fly   989 DEMKRQQH-------QQIKAELR------------EMPAEG--TGDGENEPDEEEEYLIIEKEEV 1032
            .|...|:|       .|.|.|:.            |.|.||  |.|.|.|...||:.:....|.:
 Frog   771 TETTEQRHLDVLVVQSQFKEEISLNKTTSDKKTPLESPDEGITTTDMEGESPHEEKIVYQADETM 835

  Fly  1033 EQYTEDSIVEQESSMTKEEEIQKHQRDSQESEKKRKKSAEEEIEAAIAKVEAAERKARLEGASAR 1097
            |...|.:.:|:.:.||:.||                :...|::...|...|    |..| |.:..
 Frog   836 EMVDEGAAMEEPTEMTEYEE----------------EGITEKVSETIPPFE----KPTL-GRNRL 879

  Fly  1098 QDESELDVEPEQSKIKAEVQDIIATAKDIAKSRTEEQLAKPAEEELSSP-TPEEKLSKKTSDTKD 1161
            :....||::..:.| :.||.:     |.|...:.:|::.:|.:|..:|. ..|||..:|:.:..:
 Frog   880 ESMPTLDIQDLEDK-ENEVDE-----KGILDRKQKEEITEPCDEYFASTMAEEEKEGEKSVEVVE 938

  Fly  1162 DQIGAPVDVLPVNLQESLPEE---KFSATIESGATTAPTLPEDERIPLDQIKEDL-VIEEKYVKE 1222
            .   |.|:.:...::| :.||   |....:|.      ...::|.||:..:.::. ::.:.|...
 Frog   939 K---AEVEEMEEYVEE-IGEELKSKDDGEVEC------LNEQEENIPIPIVNQETDLVSKNYGNI 993

  Fly  1223 ETKEA---EAIVVATVQTLPEAAPLAIDTILA-SATKDAPKDANAEALGELPDSGERVLPMKM-- 1281
            .:|||   ...||.:..|..:.:.:..:|:.. |.|:....|.      |:.|..|..:|...
 Frog   994 MSKEASYFSGAVVTSGTTAEQISYIQDETMPGYSETEQTISDE------EIHDEQEERIPHLQYD 1052

  Fly  1282 -------------TFEAQQNLLR----------------DVIKTPDEVADLPVHEEADL----GL 1313
                         :|||...:..                :::..|..:...|:.||..:    .:
 Frog  1053 VGSYDISVPDHPGSFEAVHGIKAISSSGITTKGYILQEPEIVGYPTNIVAAPLAEEEHISSATSI 1117

  Fly  1314 YEKDSQDAGAKSISHKEESAK-EEKETDDEKENKVGEIELGDEPNKVDISHVLLKESVQEVAEKV 1377
            .|.|...:.|.|::..:..|. ...:|::..::.:    |.|..|.:..||....:.: |.....
 Frog  1118 TECDKLSSFATSVAEDQSVASITAPKTEETGKSSL----LLDTANSIPSSHTEATQGI-EYLPSA 1177

  Fly  1378 VVIETTVEKKQEEIVEATTVITQENQEDLMEQVKDKEEHEQKIESGIITEKEAKKSASTPEEKET 1442
            ..|..|...::::..::.   ..|:.:.|:...||:..|:...|     |.|........|.:..
 Frog  1178 GTISPTSSLEEDKCFKSP---PSEDFQSLISSGKDQIRHQYPAE-----EVEETHQFDKTETQHY 1234

  Fly  1443 SDI---------------TSDDELPAQLADPTTVPPKSAKDREDTGSIESPPTIEEAIEVEVQAK 1492
            |.:               |..::.|..|:|..|                      ..|:|: .:.
 Frog  1235 SSLLLCEGKDFDISYTYCTDMNKTPTHLSDEAT----------------------HFIQVD-SSF 1276

  Fly  1493 QEAQKPVPAPEEAIKTEKSPLASKETSRPESATGSVKEDTEQTKSKKSPVPSRPES------EAK 1551
            .|.::...:|:::.....||..|..||            |..|...:|||..|.||      :|.
 Frog  1277 VEGEERCLSPDDSTVKMASPTHSGPTS------------TGHTPFHQSPVEDRYESTQAELFKAA 1329

  Fly  1552 DK----------------KSP----------FAS-GEASRPESVAES----VKDEAGKAESRRES 1585
            ||                |||          .|| .|.|..|.:.::    :.|:..|....::|
 Frog  1330 DKLSHETEEKIDSKPDYDKSPENGDQYFSKTVASINEISEAEVILQAKTPLLMDDLKKDYLEKDS 1394

  Fly  1586 IAKTHKDESSLDKAKEQESRRESLAESI---KPESGIDEKSALASKEASRPESVTD--------- 1638
            |..  ||.:..::|...:.:.|..:|:.   ||:.........|..|....:.:||
 Frog  1395 IIT--KDSAIAEEADILQQQNELFSETATFGKPDDTAYSAGTYAQFEEPPGKGLTDSFTSEHIMI 1457

  Fly  1639 -KSKEPSRRESIAESLKAESTKDEKSAPPSKEASRPGSVVES--VKDETEKSKEPSRRESIAESA 1700
             |..|.....|:       |||:..|     |.::..|.:|.  :|||.  ::|.|.::.:.|..
 Frog  1458 QKQTELGLFHSV-------STKELPS-----EDTKCASYLEQSPIKDEI--TQENSSQDILLEDT 1508

  Fly  1701 KPPIEFREVSRPESVIDGIKDESAKPESRRDSPLASKEASRPESVLESVKDEPIKSTEKSRRESV 1765
            | .:.|.|..:.:       |.|.:......||:.::...     :...|||.::: |||
 Frog  1509 K-SLSFTEQGKED-------DTSLQMSLIEQSPIINETCQ-----ITPAKDEFLEN-EKS----- 1554

  Fly  1766 AESFKADSTKDEKSPLTSKDISRPESAVENVMDAVGSAERSQPESVTASRDVSRP--------ES 1822
                 .|..|..|....|.|...|     ..:|.:.|.|.:..:..|...|..:|        .:
 Frog  1555 -----LDLIKQTKDYKCSFDDMSP-----GYVDPLQSIEETLTQDKTHLEDYGKPSLDHAQVFSA 1609

  Fly  1823 VAESEKDDTDKPESVVESVIPASDVVEIEKGAADKEKGVFVSLEIGKPDSPSEVIS--------R 1879
            |:..:||.:.:|   :..|.||.|:....|....:::..|::|....||. ||.:|        .
 Frog  1610 VSGIQKDVSPEP---LPEVYPADDMDSDFKQQMHQKEDTFLALSSSSPDD-SESLSLADHKSPLE 1670

  Fly  1880 PGPVVESVKPESRRESSTEIVLPCHAEDSKEPSRPESKVECLKDESEVLKGSTRRESV-----AE 1939
            .|....|:.|....|.|.|:                        |::.:|..|..:.|     .|
 Frog  1671 TGGNSHSLTPSGIEEQSAEM------------------------ENDYMKQLTSEKRVWFTEGNE 1711

  Fly  1940 SDKSSQPFKETSRPESAVGSMKDES--MSKEPSRRESVKDGAAQSRETSRPAS--VAESAKDGAD 2000
            |.:.....:.|.:.||   :..||:  ...|.:.|....|   ||...:..|:  |||.|....|
 Frog  1712 SGRKENKLRYTEQGES---TFLDEAHDWDGESALRSDFSD---QSTPDTEDANNLVAEYAHFHKD 1770

  Fly  2001 DLKELSRPESTTQSKE--AGSIKDEKSPL------------ASEEASRPASVAESVKDEAEKSKE 2051
                   .|.|.:|.:  |..:.|....|            .|||..:.:.|..|...|....|.
 Frog  1771 -------TEHTPESMDISANILSDNSKTLCQDTILHTEIVYGSEEKEKKSYVDTSSPPELCSEKL 1828

  Fly  2052 ESRRESVAEKSPLPSKEASRPASVAESIK----DEAEKSKEE---SRRESVAEKSPLPSKEASRP 2109
            .:..:|:.:|...|....|:.:...|.||    ||.:...:|   |..:.:.:...|..:.::..
 Frog  1829 PTDSDSLFDKGFYPDSSLSKVSFEGEEIKKSTVDETQSFADEHIYSYEKPMYDIQDLTREISTSD 1893

  Fly  2110 ASVAESIKDEAEKSKEESRRESVAEKSPLPSKE---ASRPA-------SVAESIKDEAEKSKEES 2164
            |.:...::..:...|.:   :|:....|:.:||   ||.|.       ::.:.||.|..||..:.
 Frog  1894 ADILTGMQTVSFLDKYD---DSLGADVPISTKEITVASSPQEQTEVVFTIDKEIKHEPYKSPTKE 1955

  Fly  2165 RRESVAEKSPLPSKEASRPASVAESIKDEAE----KSKEESRRESVAEKSPLPSKEASRPASVAE 2225
            ..:...|.|...|...| ..::|..:.|..:    |..::|...|::.......|::..|..:..
 Frog  1956 TEQEYVETSYAESSSLS-GFTLATHLDDVTDNMFLKQDKKSSPSSLSYPEETSVKKSLSPCQLYP 2019

  Fly  2226 SIKDEAEKSKEESRRESVAEKSPLPSKEASRPASVAESIK----------DEAEK-----SKEES 2275
            ..||....||:.:..|  .|.:|.|..:..:.|.:.|.|.          :|.|.     .::|:
 Frog  2020 QEKDIYGSSKKSAAEE--REPTPYPDDKTFQYADIYEKIVSGVSHTDHIIEEVEPYSAGYLEKEN 2082

  Fly  2276 RRESVAEKSPLPSKEASRPASVAESIKDEAEKSKEETRRESVAEK---SPLPSKEASRPASVAES 2337
            |..||.:...:.:..        :....|....:||::.:|..||   |||..|:.   .|:...
 Frog  2083 RAISVLDTGDVQATN--------KEFHHEMYSKEEESQLQSSKEKELSSPLSPKDT---GSITTF 2136

  Fly  2338 IKDEAEKSKEESRRESAAEKS---PLPSKEASRPASVAESVKDEADKSKEESRRESMAESGKAQS 2399
            ...|.||:...: :|.|.:|:   .|...:.::.....|:...||         ||...|..:|.
 Frog  2137 EYTEMEKTIYVA-KEKATDKTNVLGLEENQNTQSGITFETHGTEA---------ESEVSSHHSQD 2191

  Fly  2400 IKGDQSPLKEVSRPESVAESVKDDPVKSKEPSRRESVAGSVTAD---SARDDQSPLESKGASRPE 2461
            :.         |:|.:|...:.:.|:         |...::..|   ||....|.:|.|..:..:
 Frog  2192 LS---------SKPFTVDHDLHEQPM---------SYLHALHQDDNISAAKQDSDIEVKSFTAKD 2238

  Fly  2462 SVVDSVKDEAEKQESRRESKTESVIPPKAKDDKSPKEVLQPVSMTETIREDADQPMKPSQAESRR 2526
            :..       ||.|.:.||.::|.:...|| :||.||          |..|.|:       :...
 Frog  2239 TYY-------EKSEIQEESASDSELEKGAK-EKSEKE----------ITTDMDE-------KELH 2278

  Fly  2527 ESIAESIKASSPRDEKSPLASKEASRPGSVAESIKYDLDKPQIIKDDKSTEHSRRESLEDKSA-- 2589
            |:|.|..:.|.                        |.|...|       |:|....::.|:|:
 Frog  2279 ENIIEEERVSD------------------------YILHSEQ-------TQHDLNSNVHDQSSTV 2312

  Fly  2590 -VTSEKSVSRPLSVASDHEAAVAIEDDAKSSISPKDKSRPGFVAETVSSPIEEATMEFSKIEVVE 2653
             :..|.:|..|..            |:...:|....:::       |.|.||.....||
 Frog  2313 QIRGEAAVEHPTF------------DNTGYNIYENKQNK-------VFSDIEYTYCPFS------ 2352

  Fly  2654 KSSLALSLQGGSGGKLQTDSSPVDVAEGDFSHAVASVSTVTPTLTKPAELAQIGAAKTVSSPLDE 2718
                           .|.|||.|........|
 Frog  2353 ---------------AQFDSSDVTDERHQTDH--------------------------------- 2369

  Fly  2719 ALRTPSAPEHISRADSPAECASEEIASQDKSPQVL-KESSRPAWVAESKDDAAQLKSSVEDLRSP 2782
              :...:..|..:.|:..|..|  :...|::|..| :|...|.|  |...:|.
 Frog  2370 --QESQSFSHSHKEDTFLESCS--LGQNDEAPSALERELPEPKW--EYLSEAT------------ 2416

  Fly  2783 VASTEISRPASAGETASSPIEEAPKDFAE--FEQAEKAVLPLT-IELKG-NLPTLSSPVDVAHGD 2843
                     .|..||.:.|    |...:|  ||.     ||.| |...| |..|:|......|.:
 Frog  2417 ---------FSEKETYNLP----PSALSEHHFES-----LPYTGINALGTNCMTISDVATGQHDE 2463

  Fly  2844 FPQTSTPTSSPTVASVQPAEL-SKVDIEKTASSPIDEAPKSLIGCPAEERPESP---------AE 2898
            :.|.|.          :..|: |..|.....||| |.:|.||    .||:|..|         .:
 Frog  2464 YLQVSE----------RACEMDSSQDKHSMLSSP-DHSPLSL----TEEKPSIPKIPYEQYSELD 2513

  Fly  2899 SAKDAAESVE-KSKDASRP----------PSVVESTKADS-----TKGDISPSPESVLEGPKDDV 2947
            :.|:.::|:. .|.:||.|          ..::.:..||:     :..|:||...:  :..|..:
 Frog  2514 AQKEESQSISGSSSEASTPVRRDIAEGLYSHMISTYTADTEATVRSLWDVSPLVPA--DSTKPCL 2576

  Fly  2948 EKSKESSRPPSVSASI-TGDSTK----DVSRPASVVESVKDEH-DKAESRRESIAKVESVIDEAG 3006
            .:.|:|:...:.:.|. |.|:|.    :..||..::.|:.:|. ...|:...::....|::....
 Frog  2577 AEEKDSAGDHNSACSYDTDDNTLPCRIECKRPTCMMMSIMNEQMSSGETTSATMQSYSSLVPSCQ 2641

  Fly  3007 KSDSKSSSQDSQKDEK----STLASKEASRRESVVESSKDDAEKSESRPESVIASGEPVPRESKS 3067
            |.::.:::..::.:..    ..:..||.....:.|::|.|....|                   |
 Frog  2642 KEETSTANGPTEVNNSQEFFQNIQYKEGECFSAAVKTSPDSDRDS-------------------S 2687

  Fly  3068 PLDSKDT---SRPGSMVESVTAEDEKSEQQS--RRESVAESVKADTKKDGKSQEASRPSSVDELL 3127
            |...:||   :||.|::..|...:..|..||  |.|...::......:.|.|.|..|..|..|.|
 Frog  2688 PCSEEDTEKPNRPSSLMSPVHTLESYSYTQSPERTEDHGDASHEFEPRLGSSSEYERMLSSSEYL 2752

  Fly  3128 KDDDEKQESRRQSITGSHKAMSTMGDESPM---DKADKSKEPSRPESVAESIKHEN--------T 3181
            ....|...|              ..:.||:   |.:|.|::...| ||.....|.|        |
 Frog  2753 HRKGELSPS--------------FINPSPLDLSDDSDLSQDEGHP-SVKGRTHHANANTCHVQGT 2802

  Fly  3182 KDEESPLGSRRDSVAESIKSDITKGEKSPLPSKEVSRPESVVGSIKDEKAE----------SRRE 3236
            ..||:|..|..||......||:      |..::|.....:......||.|:          |...
 Frog  2803 TAEETPPTSVSDSGTSQSDSDV------PPETEECPSITADAAMDSDEDADFLPVDKAMGNSHHS 2861

  Fly  3237 SVAESVKPESS--KDATSAPPSKEHSR--PESVLGSLK-DEGDKTTSRRVSVADSIKDEKSLLVS 3296
            :..:...|..:  .|....||..:...  |::::..|. .:|||...:  .:.:..|..:..|..
 Frog  2862 NTRQGHDPHPAPMMDPQPHPPHPDVCMVDPDALVNELNFSKGDKVLKK--DLKEKNKGVRKPLTK 2924

  Fly  3297 QEASRPESEAESLKDAAAPSQETSRPESVTESVKDGKSPVASKEASRPASVAENAKDSADESKEQ 3361
            .:::.|..:|:| |.::..|::|||.               |.:.|...:.....|:||::.::.
 Frog  2925 VKSTSPARKADS-KYSSTLSKQTSRD---------------SADKSHKTTAIRKDKESAEKLQKP 2973

  Fly  3362 RPESLPQSKAGSIKDEKS 3379
            |.....|...|..|||.|
 Frog  2974 RSPMQTQFSRGEEKDEVS 2991

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
futsch	NP_001096864.1	DUF966	<1925..>2112	CDD:283735	47/216 (22%)
map1a	XP_004912694.3	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	260	1.000	Domainoid score	I1931
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	362	1.000	Inparanoid score	I2145
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm49396
Panther	1	1.100	-	-	LDO	PTHR13843
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	5.150