DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34354 and hnrnpa3

DIOPT Version :9

Sequence 1:	NP_001097953.2	Gene:	CG34354 / 5740528	FlyBaseID:	FBgn0085383	Length:	550	Species:	Drosophila melanogaster
Sequence 2:	NP_001315077.1	Gene:	hnrnpa3 / 751729	ZFINID:	ZDB-GENE-060224-1	Length:	340	Species:	Danio rerio

Alignment Length:	306	Identity:	74/306 - (24%)
Similarity:	114/306 - (37%)	Gaps:	70/306 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    89 NNSKPEQFH-IFVGDLSAEIETQQLKDAFTPFGEISDCRVVRDPQTLKSKGYGFVSFVKKSEAET 152
            ::.:|||.. :|:|.||.|.....|:..|..:|:::||.|:|||...:|:|:|||::...||.:.
Zfish     5 DSKEPEQLRKLFIGGLSFETTEDSLRAHFEQWGKLTDCVVMRDPANKRSRGFGFVTYSSVSEVDA 69

  Fly   153 AITAMNGQWLGSRSIRTNWATRKPPATK--ADMNAKPLTFDEVYNQSSPTNCTVYCGGINGALSG 215
            |:||...: :..|.:....|..:..:.|  |.:..|                .::.|||...
Zfish    70 AMTARPHK-VDGRVVEPKRAVSREDSNKPGAHLTVK----------------KIFVGGIKED--- 114

  Fly   216 FLNEEILQKTFSPYGTIQEIRVF------KDKGYAFVRFSTKEAATHAIVAVNNTEINQQ--PVK 272
             ..|..:::.|..||.|:.|.:.      |.:|:.||.|...: ....|||.....||..  .|:
Zfish   115 -TEEYHIREYFECYGKIETIDIMEERSTGKKRGFCFVTFDDHD-TVDKIVAQKYHTINSHNCEVR 177

  Fly   273 CAWGKE----SGDPNHMSAIAGGALAQGFPFGSAAAAAAAAA----------YGQQVAGY----- 318
            .|..|:    |.:..:.....|....:|..||..........          ||....||
Zfish   178 KALPKQEMQSSSNQRYRGGGGGNFTGRGGNFGRGGYGGGRGGGDGYNGFGGNYGGGPGGYGGGRG 242

  Fly   319 WYPPAPTYPAAAPASALQPGQFLQGMQ--GFTYGQFAGYQQAGYMG 362
            .|...|.|                |.|  |..:|.|..|...|..|
Zfish   243 GYGGGPGY----------------GNQGGGGGFGGFDNYNDRGNFG 272

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34354	NP_001097953.2	RRM2_TIA1_like	97..171	CDD:240799	25/74 (34%)
CG34354	NP_001097953.2	RRM3_TIA1_like	202..278	CDD:240800	21/83 (25%)
hnrnpa3	NP_001315077.1	RRM1_hnRNPA_like	14..91	CDD:241022	26/77 (34%)
		RRM2_hnRNPA3	104..183	CDD:241026	22/99 (22%)
		HnRNPA1	<296..>315	CDD:288479
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.000