DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34354 and Cstf2

DIOPT Version :9

Sequence 1:	NP_001097953.2	Gene:	CG34354 / 5740528	FlyBaseID:	FBgn0085383	Length:	550	Species:	Drosophila melanogaster
Sequence 2:	XP_038955991.1	Gene:	Cstf2 / 683927	RGDID:	1596566	Length:	624	Species:	Rattus norvegicus

Alignment Length:	393	Identity:	105/393 - (26%)
Similarity:	151/393 - (38%)	Gaps:	93/393 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    98 IFVGDLSAEIETQQLKDAFTPFGEISDCRVVRDPQTLKSKGYGFVSFVKKSEAETAITAM---NG 159
            :|||::..|...:||||.|:..|.:...|:|.|.:|.|.|||||..:   .:.|||::||   ||
  Rat    18 VFVGNIPYEATEEQLKDIFSEVGPVVSFRLVYDRETGKPKGYGFCEY---QDQETALSAMRNLNG 79

  Fly   160 QWLGSRSIRT-NWATRKPPATKADMNAKPLTFDEVYNQS-SPTNCTVYCGGINGALSGFLNEEIL 222
            :....|::|. |.|:.|.......:.......:..|.:| ||.:..   ..|:.|::....|::.
  Rat    80 REFSGRALRVDNAASEKNKEELKSLGTGAPVIESPYGESISPEDAP---ESISKAVASLPPEQMF 141

  Fly   223 ----QKTFSPYGTIQEIR--VFKDKGYAF--------VRFSTKEAATHAIVAVNNTEI----NQQ 269
                |.......:.||.|  :.::...|:        :|....|.|...:....|...    |.|
  Rat   142 ELMKQMKLCVQNSPQEARNMLLQNPQLAYALLQAQVVMRIVDPEIALKILHRQTNIPTLISGNPQ 206

  Fly   270 PVKCAWGKESGDPN-----------HMSAIAG----GA---LAQGFPFGSAAAAAAAAAYGQQVA 316
            ||..| |..|| ||           ...:::|    ||   :....|.|..|....|||    ||
  Rat   207 PVHVA-GPGSG-PNVSMNQQNPQAPQAQSLSGMHVNGAPPMMQASMPGGVPAPVQMAAA----VA 265

  Fly   317 GYWYPPAPTYPAAAPASALQPGQFLQGMQGFTYGQFAGYQQAGYMGMGVQLPGTWQSVPPQPQLA 381
            |    |.|  .:.|||..:|.   ..||||           ||.:.| .:..||.|..|..|  |
  Rat   266 G----PGP--GSLAPAGVMQA---QVGMQG-----------AGPVPM-ERGQGTLQHSPVGP--A 307

  Fly   382 SAAAATAPQ------ITQSVGSALPQAA------GVVAYPMQQFQVSPQLAEDEWLAPSLLVXLP 434
            ..|:....|      |..||..:.|...      |:...|||    .|:.|......|: .| .|
  Rat   308 GPASIERVQGQRTWMIWASVRGSTPSLLVSGGLDGIAVLPMQ----DPRAAMQRGALPA-NVPTP 367

  Fly   435 XGM 437
             |:
  Rat   368 RGL 370

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34354	NP_001097953.2	RRM2_TIA1_like	97..171	CDD:240799	29/76 (38%)
CG34354	NP_001097953.2	RRM3_TIA1_like	202..278	CDD:240800	18/93 (19%)
Cstf2	XP_038955991.1	RRM_CSTF2_CSTF2T	10..94	CDD:410072	30/78 (38%)
		CSTF2_hinge	112..191	CDD:405077	15/81 (19%)
		PRK14718	<444..>501	CDD:173181
		CSTF_C	580..620	CDD:405061
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000