Protein Alignment CG34354 and SRSF1

DIOPT Version :10

• Sequence 1: NP_001097953.2
• Gene: CG34354 / 5740528
• FlyBaseID: FBgn0085383
• Length: 550
• Species: Drosophila melanogaster
• Sequence 2: NP_008855.1
• Gene: SRSF1 / 6426
• HGNCID: 10780
• Length: 248
• Species: Homo sapiens
• Alignment Length: 212
• Identity: 46/212 - (21%)
• Similarity: 76/212 - (35%)
• Gaps: 58/212 - (27%)

  Fly    88 GNNSKPEQFHIFVGDLSAEIETQQLKDAFTPFGEISDCRVVRDPQTLKSK----GYGFVSFVKKS 148
            |||    ...|:||:|..:|.|:.::|.|..:|.|.|.       .||::    .:.||.|....
Human    12 GNN----DCRIYVGNLPPDIRTKDIEDVFYKYGAIRDI-------DLKNRRGGPPFAFVEFEDPR 65

  Fly   149 EAETAITAMNGQWLGSRSIRTNWATRKPPATKADMNAKPLTFDEVYNQSSPTNCTVYCGGINGAL 213
            :||.|:...:|.......:|..: .|....|......                     ||..||.
Human    66 DAEDAVYGRDGYDYDGYRLRVEF-PRSGRGTGRGGGG---------------------GGGGGAP 108

  Fly   214 SGFL-------NEEILQKTFSPYGTIQEIR-------------VFKDKGYAFVRFSTKEAATHAI 258
            .|..       ...::.....|.|:.|:::             |::| |...|.|..||..|:|:
Human   109 RGRYGPPSRRSENRVVVSGLPPSGSWQDLKDHMREAGDVCYADVYRD-GTGVVEFVRKEDMTYAV 172

  Fly   259 VAVNNTEINQQPVKCAW 275
            ..::||:......:.|:
Human   173 RKLDNTKFRSHEGETAY 189

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG34354	NP_001097953.2	PABP-1234	<90..420	CDD:130689	44/210 (21%)
		RRM2_TIA1_like	97..171	CDD:409789	21/77 (27%)
		RRM3_TIA1_like	202..276	CDD:409790	20/94 (21%)
SRSF1	NP_008855.1	RRM1_SRSF1	12..90	CDD:410010	24/89 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	88..134		9/67 (13%)
		RRM2_SRSF1	113..196	CDD:410160	15/78 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	191..248
		Interaction with SAFB1	198..247