Protein Alignment CG34354 and RBM23

DIOPT Version :10

• Sequence 1: NP_001097953.2
• Gene: CG34354 / 5740528
• FlyBaseID: FBgn0085383
• Length: 550
• Species: Drosophila melanogaster
• Sequence 2: NP_001339693.1
• Gene: RBM23 / 55147
• HGNCID: 20155
• Length: 483
• Species: Homo sapiens
• Alignment Length: 281
• Identity: 78/281 - (27%)
• Similarity: 116/281 - (41%)
• Gaps: 57/281 - (20%)

  Fly    89 NNSKPEQFH---IFVGDLSAEIETQQLKDAFTPFGEISDCRVVRDPQTLKSKGYGFVSFVKKSEA 150
            :|..||:..   :|...|:|.|..:.|:|.|:..|::.|.|::.|..:.:|||..:|.|.:....
Human   200 DNLSPEERDARTVFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSV 264

  Fly   151 ETAITAMNGQWLGSRSIRTNWATRKPPATKADMNAKPLTFDEVY-NQSSPTNCTVYCGGINGALS 214
            ..||.....:.||...|        ..|::|:.|......:.:. ....|....|      |:|.
Human   265 PLAIGLTGQRLLGVPII--------VQASQAEKNRLAAMANNLQKGNGGPMRLYV------GSLH 315

  Fly   215 GFLNEEILQKTFSPYGTIQEIRVFKD------KGYAFVRFSTKEAATHAIVAVNNTEINQQPVKC 273
            ..:.|::|:..|.|:|.|..|.:.||      |||.|:.||..|.|..|:..:|..|:..:|::.
Human   316 FNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQLNGFELAGRPMRV 380

  Fly   274 AWGKE-----------SGDPNHMSAIAGG------ALAQG----FPFGSAAAAAAAA-AYGQQVA 316
            ....|           .||.......|||      .||:|    .|..:|||||||| |...|:.
Human   381 GHVTERLDGGTDITFPDGDQELDLGSAGGRFQLMAKLAEGAGIQLPSTAAAAAAAAAQAAALQLN 445

  Fly   317 GYWYPPAPTYPAAAPASALQP 337
            |           |.|..||.|
Human   446 G-----------AVPLGALNP 455

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG34354	NP_001097953.2	PABP-1234	<90..420	CDD:130689	78/280 (28%)
		RRM2_TIA1_like	97..171	CDD:409789	21/76 (28%)
		RRM3_TIA1_like	202..276	CDD:409790	24/79 (30%)
RBM23	NP_001339693.1	SF-CC1	143..482	CDD:273721	78/281 (28%)