DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34354 and trv

DIOPT Version :9

Sequence 1:	NP_001097953.2	Gene:	CG34354 / 5740528	FlyBaseID:	FBgn0085383	Length:	550	Species:	Drosophila melanogaster
Sequence 2:	NP_001163754.3	Gene:	trv / 43362	FlyBaseID:	FBgn0085391	Length:	651	Species:	Drosophila melanogaster

Alignment Length:	488	Identity:	273/488 - (55%)
Similarity:	317/488 - (64%)	Gaps:	99/488 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MLTMSTLMMPAPTI---------AMGAPQITMGPHKPP---ETKLLAIHPAAAAAAAAQQQQQSV 53
            |||....||..|.:         :.|.|..:..|..||   ..::.::..|||||.:|.|:...:
  Fly   186 MLTHFQAMMQPPPLPPSPMMPPQSFGCPLPSRTPATPPLPGTYRVQSLKSAAAAAVSAYQRNGKL 250

  Fly    54 T---------------------------------AAHLQHNGQQQHSQQQQQQQMSQQQQQQQQQ 85
            .                                 ||..:..||......::.:.|....
  Fly   251 PRNLPALRAMEMALRTNSFATPPAPHSLPLPPPHAARTEGGGQDMEDSDEEMEYMPPLH------ 309

  Fly    86 LVGNNSKPEQFHIFVGDLSAEIETQQLKDAFTPFGEISDCRVVRDPQTLKSKGYGFVSFVKKSEA 150
                    :||||||||||:|||||||::||||||||||||||||||||||||||||||:|||||
  Fly   310 --------KQFHIFVGDLSSEIETQQLREAFTPFGEISDCRVVRDPQTLKSKGYGFVSFIKKSEA 366

  Fly   151 ETAITAMNGQWLGSRSIRTNWATRKPPATKADMNAKPLTFDEVYNQSSPTNCTVYCGGINGALSG 215
            |:||||||||||||||||||||||||||:|.  |.||||||||||||||:|||||.||:|.||:.
  Fly   367 ESAITAMNGQWLGSRSIRTNWATRKPPASKE--NIKPLTFDEVYNQSSPSNCTVYVGGVNSALTA 429

  Fly   216 FLNEEILQKTFSPYGTIQEIRVFKDKGYAFVRFSTKEAATHAIVAVNNTEINQQPVKCAWGKESG 280
             |:||:|||||:|||.||||||||||||||||||||||||||||.|:|||||.|||||:||||||
  Fly   430 -LSEEVLQKTFAPYGAIQEIRVFKDKGYAFVRFSTKEAATHAIVGVHNTEINAQPVKCSWGKESG 493

  Fly   281 DPNHMSAIAGGAL------AQGFPFGSAAAAAAAAAYGQQVA--GYWYPPAPTY----------- 326
            |||:...||..||      |.|||:| ..|||||||||||:|  |.||.|.|||
  Fly   494 DPNNAQTIATQALNSAAAAAAGFPYG-VGAAAAAAAYGQQLAATGCWYSPTPTYPASSATAAAVT 557

  Fly   327 PAAAPASALQPGQFLQGMQGFTYGQFAGYQQAGYMGMGVQLPGTWQSV-----PPQPQLASAAAA 386
            ||||.|:|:| .|||||:||:.:||:.|||| ||||||||:|.|||.|     .|..|||:..|
  Fly   558 PAAASAAAVQ-NQFLQGIQGYHFGQYGGYQQ-GYMGMGVQIPATWQGVTQAQISPAQQLATGVA- 619

  Fly   387 TAPQITQSVGSALPQAAGVVAYPMQQFQVSPQL 419
                     |:|:||||||||||:||||||||:
  Fly   620 ---------GTAIPQAAGVVAYPIQQFQVSPQV 643

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34354	NP_001097953.2	RRM2_TIA1_like	97..171	CDD:240799	68/73 (93%)
CG34354	NP_001097953.2	RRM3_TIA1_like	202..278	CDD:240800	61/75 (81%)
trv	NP_001163754.3	RRM2_TIA1_like	313..387	CDD:240799	68/73 (93%)
trv	NP_001163754.3	RRM3_TIA1_like	416..491	CDD:240800	61/75 (81%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	77	1.000	Domainoid score	I3083
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	189	1.000	Inparanoid score	I1394
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D100171at50557
OrthoFinder	1	1.000	-	-		FOG0000924
OrthoInspector	1	1.000	-	-		mtm1150
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10352
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X831
	8	8.070