DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34354 and SPBC23E6.01c

DIOPT Version :9

Sequence 1:	NP_001097953.2	Gene:	CG34354 / 5740528	FlyBaseID:	FBgn0085383	Length:	550	Species:	Drosophila melanogaster
Sequence 2:	NP_596601.2	Gene:	SPBC23E6.01c / 2540551	PomBaseID:	SPBC23E6.01c	Length:	473	Species:	Schizosaccharomyces pombe

Alignment Length:	352	Identity:	87/352 - (24%)
Similarity:	137/352 - (38%)	Gaps:	96/352 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    91 SKPEQFHIFVGDLSAEIETQQLKDAF-TPFGEISDCRVVRDPQTLKSKGYGFVSFVKKSEAETAI 154
            ||..::.|||||||..:....:...| :.:......:::.||||..|:|||||.|..:::.::|:
pombe   181 SKASEYSIFVGDLSPNVNEFDVYSLFASRYNSCKSAKIMTDPQTNVSRGYGFVRFTDENDQKSAL 245

  Fly   155 TAMNGQWLGSRSIRTNWATRKPPATKA----DMNAKPLTFDEV--YNQSSP-------TNCTVYC 206
            ..|.||..|.|.||...||   |.:||    .:|..|::...|  |:.:.|       .|.||:.
pombe   246 AEMQGQICGDRPIRVGLAT---PKSKAHVFSPVNVVPVSMPPVGFYSAAQPVPQFADTANSTVFV 307

  Fly   207 GGINGALSGFLNEEILQKTFSPYGTIQEIRVFKDKGYAFVRFSTKEAATHAIVAVNNTEINQQPV 271
            ||    ||.|::||.|:..|..:|.|..:::...||..||:|..:::|..||..:....:....:
pombe   308 GG----LSKFVSEEELKYLFQNFGEIVYVKIPPGKGCGFVQFVNRQSAEIAINQLQGYPLGNSRI 368

  Fly   272 KCAWGKESGDPNHMSAIAGGALAQGFPFGSAAAAAAAAAYGQQVAGYWYPPAPTYPAAAPASALQ 336
            :.:||:...                      ..||.|..|..||:....|....:||
pombe   369 RLSWGRNQN----------------------PIAAPALNYQSQVSQTTIPATSLFPA-------- 403

  Fly   337 PGQFLQGMQGFTYGQFAGYQQAGYMGMGVQLPGTWQSVPPQPQLAS-AAAATAPQITQSVGSALP 400
                                               .|:|||.|.:. .|.|.:|...|:.|:.:.
pombe   404 -----------------------------------MSLPPQAQFSPYPAVAPSPLALQTRGAPIG 433

  Fly   401 QAAGVVAYPMQQFQVSPQLAEDEWLAP 427
            ....:         .||.|..|:...|
pombe   434 MEISI---------GSPALVPDQMHIP 451

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34354	NP_001097953.2	RRM2_TIA1_like	97..171	CDD:240799	27/74 (36%)
CG34354	NP_001097953.2	RRM3_TIA1_like	202..278	CDD:240800	23/75 (31%)
SPBC23E6.01c	NP_596601.2	RRM	70..376	CDD:223796	63/201 (31%)
		RRM1_NGR1_NAM8_like	94..173	CDD:241055
		RRM2_NGR1_NAM8_like	185..264	CDD:241057	27/78 (35%)
		RRM3_NGR1_NAM8_like	302..373	CDD:240792	22/74 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	112	1.000	Inparanoid score	I1562
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.960