DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG34354 and Tial1

DIOPT Version :10

Sequence 1:NP_001097953.2 Gene:CG34354 / 5740528 FlyBaseID:FBgn0085383 Length:550 Species:Drosophila melanogaster
Sequence 2:NP_033409.1 Gene:Tial1 / 21843 MGIID:107913 Length:392 Species:Mus musculus


Alignment Length:417 Identity:170/417 - (40%)
Similarity:204/417 - (48%) Gaps:109/417 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly    37 HPAAAAAAAAQQQQQSVTAAHLQHNGQQQHSQQQQQQQMSQQQQQQQQQLVGNNSKPEQFHIFVG 101
            |..||||.||.             ||::...::.:....:....|::       .....||:|||
Mouse    75 HRDAAAALAAM-------------NGRKILGKEVKVNWATTPSSQKK-------DTSNHFHVFVG 119

  Fly   102 DLSAEIETQQLKDAFTPFGEISDCRVVRDPQTLKSKGYGFVSFVKKSEAETAITAMNGQWLGSRS 166
            |||.||.|:.:|.||.|||:|||.|||:|..|.||||||||||..|.:||.||..|.|||||.|.
Mouse   120 DLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQ 184

  Fly   167 IRTNWATRKPPATKA--DMNAKPLTFDEVYNQSSPTNCTVYCGGINGALSGFLNEEILQKTFSPY 229
            ||||||||||||.|:  :.|.|.|.|::|.|||||.|||||||||   .|| |.::::::||||:
Mouse   185 IRTNWATRKPPAPKSTQETNTKQLRFEDVVNQSSPKNCTVYCGGI---ASG-LTDQLMRQTFSPF 245

  Fly   230 GTIQEIRVFKDKGYAFVRFSTKEAATHAIVAVNNTEINQQPVKCAWGKESGDP----NHMSAIAG 290
            |.|.|||||.:|||:||||||.|:|.||||:||.|.|....|||.|||||.|.    ..:.....
Mouse   246 GQIMEIRVFPEKGYSFVRFSTHESAAHAIVSVNGTTIEGHVVKCYWGKESPDMTKNFQQVDYSQW 310

  Fly   291 GALAQ--GFPFGSAAAAAAAAAYGQQVAGYW-YPPAPTYPAAAPASALQPGQFLQGMQGFTYGQF 352
            |..:|  |.|          ..|||.:|..| .||...|.        ||    ...|||...| 
Mouse   311 GQWSQVYGNP----------QQYGQYMANGWQVPPYGVYG--------QP----WNQQGFGVDQ- 352

  Fly   353 AGYQQAGYM-GMGVQLPGTWQSVPPQPQLASAAAATAPQITQSVGSALPQAAGVVAYPMQQFQVS 416
              ...|.:| |.|.|        |||.|      |..|.|..      |..||            
Mouse   353 --SPSAAWMGGFGAQ--------PPQGQ------APPPVIPP------PNQAG------------ 383

  Fly   417 PQLAEDEWLAPSLLVXLPXGMAMYPTQ 443
                               |||.:|||
Mouse   384 ------------------YGMASFPTQ 392

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG34354NP_001097953.2 PABP-1234 <90..420 CDD:130689 154/339 (45%)
RRM2_TIA1_like 97..171 CDD:409789 49/73 (67%)
RRM3_TIA1_like 202..276 CDD:409790 44/73 (60%)
Tial1NP_033409.1 RRM1_TIAR 10..107 CDD:410028 9/44 (20%)
RRM2_TIAR 113..192 CDD:410029 53/78 (68%)
RRM3_TIAR 222..294 CDD:241064 46/75 (61%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 363..392 16/78 (21%)

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