Protein Alignment CG34354 and CIRBP

DIOPT Version :10

• Sequence 1: NP_001097953.2
• Gene: CG34354 / 5740528
• FlyBaseID: FBgn0085383
• Length: 550
• Species: Drosophila melanogaster
• Sequence 2: NP_001287758.1
• Gene: CIRBP / 1153
• HGNCID: 1982
• Length: 297
• Species: Homo sapiens
• Alignment Length: 345
• Identity: 79/345 - (22%)
• Similarity: 121/345 - (35%)
• Gaps: 107/345 - (31%)

  Fly    98 IFVGDLSAEIETQQLKDAFTPFGEISDCRVVRDPQTLKSKGYGFVSFVKKSEAETAITAMNGQWL 162
            :|||.||.:...|.|:..|:.:|:||:..||:|.:|.:|:|:|||:|....:|:.|:.||||:.:
Human     8 LFVGGLSFDTNEQSLEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAKDAMMAMNGKSV 72

  Fly   163 GSRSIRTNWATRKPPATKADMNAKPLTFDEVYNQSSPTNCTVYCGGINGALSGFLNEEILQKTFS 227
            ..|.||.:.|                      .:||......|.||..|....|.......:.||
Human    73 DGRQIRVDQA----------------------GKSSDNRSRGYRGGSAGGRGFFRGGRGRGRGFS 115

  Fly   228 PYGTIQEIRVFKDKGYAFVRFSTKEAATHAIVAVNNTEINQQPVKCAWGKESGDPNHMSA----- 287
            ..|        .|:||...||.::.                       |...|..::.|:
Human   116 RGG--------GDRGYGGNRFESRS-----------------------GGYGGSRDYYSSRSQSG 149

  Fly   288 -----IAGGALAQGF-PFGSAAAAAAAAAYGQQVAGYWYPPAPT------------YPAAA---- 330
                 .:||:....: .:|.:.:..|...:....|.:...|:|:            .|..|
Human   150 GYSDRSSGGSYRDSYDSYGKSHSEGATLLWPAVGARFTLVPSPSTLGWTLRPCHCACPEEAHLSS 214

  Fly   331 ----------PASALQPGQFLQGMQGFTYGQFAGYQQAGYMGMGVQLPGTWQSVPPQPQLASAAA 385
                      |....|.|:..:|..|.:.....|.:.|.....|..|||.    .|:|.|||
Human   215 QSHFYRRTQKPNETDQKGKGERGPAGQSARCMCGRRPASLGCGGWLLPGR----RPRPGLAS--- 272

  Fly   386 ATAPQITQSVGSALPQAAGV 405
                      |..||..|.|
Human   273 ----------GVKLPLVASV 282

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG34354	NP_001097953.2	PABP-1234	<90..420	CDD:130689	79/345 (23%)
		RRM2_TIA1_like	97..171	CDD:409789	30/72 (42%)
		RRM3_TIA1_like	202..276	CDD:409790	13/73 (18%)
CIRBP	NP_001287758.1	RRM_CIRBP_RBM3	6..85	CDD:409883	31/98 (32%)