DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG44837 and CG5282

DIOPT Version :9

Sequence 1:	NP_001287037.1	Gene:	CG44837 / 5740513	FlyBaseID:	FBgn0266100	Length:	964	Species:	Drosophila melanogaster
Sequence 2:	NP_649221.1	Gene:	CG5282 / 40256	FlyBaseID:	FBgn0036986	Length:	451	Species:	Drosophila melanogaster

Alignment Length:	566	Identity:	159/566 - (28%)
Similarity:	238/566 - (42%)	Gaps:	163/566 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   433 LEQHIKHCSCSCNHMGYGNSMDY----QTTGFGGLPDVTEHSNIRRTLSRQNSISNSDSGGEIAS 493
            |.||..||...|  ..:....|.    :.|.|||                         |.|
  Fly    15 LHQHQPHCKQQC--FVFTEIADIELPAEITKFGG-------------------------GNE--- 49

  Fly   494 IQKSKVNFGNPLAGGVVVGGDIVGLDAKSPTSLGSTTGAGATGKAKGKASRKANAGPDGGQKGRR 558
                |:...|   ||:             ||..........:...:.:.||           ||:
  Fly    50 ----KIRCSN---GGI-------------PTYSSKKDSCSESSAERPERSR-----------GRK 83

  Fly   559 -----GSWLVAITLVSAICLLAIAATLAYQHFLMAPSRNSHAQRLRIVRRILREVPLVDGHNNYA 618
                 |..||.|.:...|   .:|..|.....|.|        ||..:||:|.|.||::|    :
  Fly    84 ILLGVGVVLVCIAMAGGI---PLALQLRSSSLLEA--------RLAFIRRLLTESPLIEG----S 133

  Fly   619 WNVRKYAHSSLELHLSHDVDHKSLWSRPAWAQTDMERLKQGLVSVQVWSAYVPCEAQGLDAVQLA 683
            |.    ..|::.|:.|                 ::..::|..:...:|...|||.||.||||||.
  Fly   134 WK----PPSTMSLNSS-----------------NLFEVRQNHIGAVLWPIAVPCGAQYLDAVQLT 177

  Fly   684 LEQIDIVRRLSDMYARETVLATSSQDIVDA-------HRRGLLASLIGVEGGHTIGSSLGVLRSF 741
            ||.||..:|::        .||.|..||::       |.||.:|.|:|:.|||.:|:|..||||.
  Fly   178 LEGIDRAKRIT--------AATDSMHIVESADEMEQTHIRGEVAVLMGISGGHALGTSTAVLRSI 234

  Fly   742 YSLGARYLSLTH-RCDVSWAGSSASP----AEQGLT----PFGKAIVREMNRLGMMIDLSHSSDA 797
            |.||||::|:|. .|...||.::...    .|:.:|    .||:.::.|||||||::::|..|:|
  Fly   235 YLLGARFVSITSLECTTPWAAAAIRRPDYLVEENVTNSFNEFGQTMLFEMNRLGMLVEISMLSEA 299

  Fly   798 TARDVLQVTRAPVIFSHSAARQLCNSTR--NVPDDILRLVAENGGLIMLSFDSEDVACG-RQARL 859
            ....||:..:|||:.:::....:|||:.  ::||.:|.|:.||||:|:|:.:    .|| |...:
  Fly   300 AMLAVLKTAKAPVLLTNATPLSMCNSSNIASIPDHVLSLLPENGGVILLNLE----RCGDRTLGV 360

  Fly   860 QDVIEHIKYVRAIAGIQHIGLGAGYDGIELPPLGLEDVSKYPELLAALLEDHNWSEEDVAMLAGR 924
            ::.|..|.|||.:||:.|||||..             ...|..|||.|..|..|....:..|.|.
  Fly   361 REAITAINYVRKVAGVDHIGLGGA-------------PKSYALLLAELARDRVWGNAAIKKLVGG 412

  Fly   925 NFLRIMETVETVR------DYWKRAAIQPIEQTEPQPKTQCTYMSS 964
            |.:||:..:||::      :.|       |.....:..:.|.|..|
  Fly   413 NVMRILREIETLKNRLPLYEEW-------IPHESIESNSYCRYPES 451

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG44837	NP_001287037.1	rDP_like	609..929	CDD:238626	112/338 (33%)
CG5282	NP_649221.1	Peptidase_M19	123..420	CDD:395996	116/346 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1272387at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10443
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	3.020