DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG44837 and DPEP1

DIOPT Version :9

Sequence 1:	NP_001287037.1	Gene:	CG44837 / 5740513	FlyBaseID:	FBgn0266100	Length:	964	Species:	Drosophila melanogaster
Sequence 2:	NP_001121613.1	Gene:	DPEP1 / 1800	HGNCID:	3002	Length:	411	Species:	Homo sapiens

Alignment Length:	369	Identity:	159/369 - (43%)
Similarity:	230/369 - (62%)	Gaps:	16/369 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   603 RILREVPLVDGHNNYAWNVRKYAHSSLELHLSHDVDHKSLWSRPAWAQTDMERLKQGLVSVQVWS 667
            ||:|:.|::||||:..|.:....::.|:       |.::..:..|...|::.:|:.|.|..|.||
Human    25 RIMRDSPVIDGHNDLPWQLLDMFNNRLQ-------DERANLTTLAGTHTNIPKLRAGFVGGQFWS 82

  Fly   668 AYVPCEAQGLDAVQLALEQIDIVRRLSDMYARETVLATSSQDIVDAHRRGLLASLIGVEGGHTIG 732
            .|.||:.|..|||:..|||:|:|.|:..||....:..|||..|..|.|.|.:||||||||||:|.
Human    83 VYTPCDTQNKDAVRRTLEQMDVVHRMCRMYPETFLYVTSSAGIRQAFREGKVASLIGVEGGHSID 147

  Fly   733 SSLGVLRSFYSLGARYLSLTHRCDVSWAGS------SASPAEQGLTPFGKAIVREMNRLGMMIDL 791
            |||||||:.|.||.|||:|||.|:..||.:      .:.|..|||:|||:.:|:|:||||::|||
Human   148 SSLGVLRALYQLGMRYLTLTHSCNTPWADNWLVDTGDSEPQSQGLSPFGQRVVKELNRLGVLIDL 212

  Fly   792 SHSSDATARDVLQVTRAPVIFSHSAARQLCNSTRNVPDDILRLVAENGGLIMLSFDSEDVACGRQ 856
            :|.|.||.:..||::|||||||||:|..:|.|.||||||:||||.:...|:|::|.:..::|..:
Human   213 AHVSVATMKATLQLSRAPVIFSHSSAYSVCASRRNVPDDVLRLVKQTDSLVMVNFYNNYISCTNK 277

  Fly   857 ARLQDVIEHIKYVRAIAGIQHIGLGAGYDGIELPPLGLEDVSKYPELLAALLEDHNWSEEDVAML 921
            |.|..|.:|:.:::.:||.:.:|.|..:||:...|.|||||||||:|:|.||. .||:|.:|...
Human   278 ANLSQVADHLDHIKEVAGARAVGFGGDFDGVPRVPEGLEDVSKYPDLIAELLR-RNWTEAEVKGA 341

  Fly   922 AGRNFLRIMETVETVRDYWKRAAIQPI--EQTEPQPKTQCTYMS 963
            ...|.||:.|.||...:..:....:||  :|.....:|...|.|
Human   342 LADNLLRVFEAVEQASNLTQAPEEEPIPLDQLGGSCRTHYGYSS 385

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG44837	NP_001287037.1	rDP_like	609..929	CDD:238626	146/325 (45%)
DPEP1	NP_001121613.1	Peptidase_M19	26..352	CDD:395996	149/333 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165155231
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1272387at2759
OrthoFinder	1	1.000	-	-		FOG0001225
OrthoInspector	1	1.000	-	-		otm42184
orthoMCL	1	0.900	-	-		OOG6_102004
Panther	1	1.100	-	-	O	PTHR10443
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.850