| Sequence 1: | NP_001285192.1 | Gene: | Lgr4 / 5740505 | FlyBaseID: | FBgn0085440 | Length: | 809 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001017403.1 | Gene: | LGR6 / 59352 | HGNCID: | 19719 | Length: | 967 | Species: | Homo sapiens |
| Alignment Length: | 836 | Identity: | 186/836 - (22%) |
|---|---|---|---|
| Similarity: | 280/836 - (33%) | Gaps: | 277/836 - (33%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 162 CPCRGDEIL----C---------------------RFQQLTDIPERLPQH--DLATLDLTGNNFE 199
Fly 200 TIHETFFS------------------------ELPDVDSLVLKFCSIREIASHAFDRLADNPLRT 240
Fly 241 LYMDD------------------------NKLPHLPEHFFPEGNQLSILILARNHLHHLKRSDFL 281
Fly 282 NLQKLQELDLRGNRIGNFEAEV------------------------------------------- 303
Fly 304 ----FARLPNLEVLYLNE-------NHLK---------------RLDPDRFPRTLLNLHTLSLAY 342
Fly 343 NQIEDIAANTFPFPRLRYLFLAGNRLSHIRDETFCNLSNLQGLHLNENRIEGFDLEAFACLKNLS 407
Fly 408 SLLLTGNRFQTL-------------------------DSRVLKNLTSLDYIYFSWFHLCSAAMNV 447
Fly 448 RVCDPHGDGISSKLHLLDNQI-------------------------------------------- 468
Fly 469 ------------LRGSVWVMASIAVVGNLLVLLGRYFYKSRSNVEHSLYLRHLAASDFLMGIYLT 521
Fly 522 LIACADISFRGEYIKYEETWRHSGVCAFAGFLSTFSCQSSTLLLTLVTWDRLMSVT--RPL-KPR 583
Fly 584 DTEKVRI-VLRLLLLWGISFGLAAAPLLPNPYFGSHFYGNNGVCLSLHIHDPYAKGWEYSALL-- 645
Fly 646 ---FILVNTLSLIFILFSYIRM--------LQAIRDSGGGMRSTHSGRENVVATRFAIIVTTDCA 699
Fly 700 CWLPIIVVKLAALSGC-EISPDLYAWLAVLVLPVNSALNPVLYTLTTAAFKQQLRR 754 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Lgr4 | NP_001285192.1 | Ldl_recept_a | 87..124 | CDD:278486 | |
| LRR_RI | <184..397 | CDD:238064 | 76/331 (23%) | ||
| LRR_8 | 188..248 | CDD:290566 | 23/107 (21%) | ||
| leucine-rich repeat | 188..211 | CDD:275380 | 10/46 (22%) | ||
| leucine-rich repeat | 212..235 | CDD:275380 | 6/22 (27%) | ||
| leucine-rich repeat | 238..261 | CDD:275380 | 9/46 (20%) | ||
| LRR_8 | 261..320 | CDD:290566 | 21/112 (19%) | ||
| leucine-rich repeat | 262..285 | CDD:275380 | 8/22 (36%) | ||
| LRR_4 | 284..325 | CDD:289563 | 17/109 (16%) | ||
| leucine-rich repeat | 286..309 | CDD:275380 | 8/69 (12%) | ||
| LRR_4 | 308..348 | CDD:289563 | 18/61 (30%) | ||
| leucine-rich repeat | 310..334 | CDD:275380 | 10/45 (22%) | ||
| leucine-rich repeat | 335..357 | CDD:275380 | 7/21 (33%) | ||
| LRR_8 | 356..416 | CDD:290566 | 24/59 (41%) | ||
| leucine-rich repeat | 358..381 | CDD:275380 | 8/22 (36%) | ||
| LRR_4 | 381..421 | CDD:289563 | 17/64 (27%) | ||
| leucine-rich repeat | 382..405 | CDD:275380 | 10/22 (45%) | ||
| leucine-rich repeat | 406..427 | CDD:275380 | 9/45 (20%) | ||
| 7tm_1 | 483..741 | CDD:278431 | 69/275 (25%) | ||
| LGR6 | NP_001017403.1 | LRRNT | 34..68 | CDD:214470 | 5/28 (18%) |
| LRR_RI | <57..199 | CDD:238064 | 27/143 (19%) | ||
| leucine-rich repeat | 70..91 | CDD:275380 | 4/20 (20%) | ||
| LRR 1 | 91..112 | 7/20 (35%) | |||
| LRR_8 | 92..150 | CDD:290566 | 14/57 (25%) | ||
| leucine-rich repeat | 92..115 | CDD:275380 | 8/22 (36%) | ||
| LRR 2 | 115..136 | 0/20 (0%) | |||
| leucine-rich repeat | 116..139 | CDD:275380 | 2/22 (9%) | ||
| LRR_RI | 131..392 | CDD:238064 | 57/263 (22%) | ||
| LRR 3 | 139..160 | 5/20 (25%) | |||
| leucine-rich repeat | 140..163 | CDD:275380 | 6/22 (27%) | ||
| LRR 4 | 163..186 | 5/24 (21%) | |||
| leucine-rich repeat | 164..187 | CDD:275380 | 5/22 (23%) | ||
| LRR_8 | 186..246 | CDD:290566 | 17/59 (29%) | ||
| LRR 5 | 187..208 | 4/20 (20%) | |||
| leucine-rich repeat | 188..211 | CDD:275380 | 4/22 (18%) | ||
| LRR 6 | 211..232 | 7/20 (35%) | |||
| leucine-rich repeat | 212..235 | CDD:275380 | 8/22 (36%) | ||
| LRR 7 | 235..256 | 6/20 (30%) | |||
| leucine-rich repeat | 236..258 | CDD:275380 | 6/21 (29%) | ||
| LRR_8 | 258..314 | CDD:290566 | 6/55 (11%) | ||
| LRR 8 | 258..279 | 0/20 (0%) | |||
| leucine-rich repeat | 259..282 | CDD:275380 | 0/22 (0%) | ||
| LRR 9 | 282..303 | 1/20 (5%) | |||
| leucine-rich repeat | 283..304 | CDD:275380 | 1/20 (5%) | ||
| LRR 10 | 306..328 | 6/21 (29%) | |||
| LRR 11 | 329..350 | 3/20 (15%) | |||
| leucine-rich repeat | 330..344 | CDD:275378 | 2/13 (15%) | ||
| LRR 12 | 353..374 | 7/21 (33%) | |||
| leucine-rich repeat | 354..399 | CDD:275380 | 15/45 (33%) | ||
| LRR_8 | 375..434 | CDD:290566 | 24/58 (41%) | ||
| LRR 13 | 375..396 | 7/20 (35%) | |||
| leucine-rich repeat | 376..390 | CDD:275378 | 4/13 (31%) | ||
| LRR 14 | 399..420 | 9/20 (45%) | |||
| leucine-rich repeat | 400..423 | CDD:275380 | 10/22 (45%) | ||
| LRR 15 | 423..443 | 7/19 (37%) | |||
| leucine-rich repeat | 424..444 | CDD:275380 | 7/19 (37%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_KOG2087 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.810 | |||||