| Sequence 1: | NP_001285192.1 | Gene: | Lgr4 / 5740505 | FlyBaseID: | FBgn0085440 | Length: | 809 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_037020.2 | Gene: | Tshr / 25360 | RGDID: | 3911 | Length: | 764 | Species: | Rattus norvegicus |
| Alignment Length: | 767 | Identity: | 182/767 - (23%) |
|---|---|---|---|
| Similarity: | 295/767 - (38%) | Gaps: | 197/767 - (25%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 148 LRIGECLWPNENFSCPC---RGDEILCRFQQLTDIPERLPQHDLATLDLTGNNFETIHETFFSEL 209
Fly 210 PDVDSLVLKF-CSIREIASHAFDRLAD-------NPLRTLYMDDNKLPHLP-----------EHF 255
Fly 256 FPEGNQL------SILILARN-HLHHLKRSDFLNL-QKLQELDLRGNRIGNFEAEVFARLPNLEV 312
Fly 313 LYLNEN-HLKRLDPDRF------PRTLLNLHTLSLA-------YNQIEDIAANTFPFPR----LR 359
Fly 360 YLFLAGNRLSH---------------IRDETFCNLSNLQGL------------------------ 385
Fly 386 HL-----------------------NENRIEGFDLEAFACLKNLSSLLLTGNRFQTLDSRVLKNL 427
Fly 428 TSLDYIYFSWFHLCSAAMNVRVCDPHGDGISSKLHLLDNQILRGSVWVMASIAVVGNLLVLLGRY 492
Fly 493 FYKSRSNVEHSLYLRHLAASDFLMGIYLTLIACADISFRGEYIKYEETWRHSGVCAFAGFLSTFS 557
Fly 558 CQSSTLLLTLVTWDRLMSVTRPLKPRDTEKVRIVLRLLLL---WGISFGLAAAPLLPNPYFGSHF 619
Fly 620 YGNNGVCLSLHIHDPYAKGWEYSALLFILVNTLSLIFILFSYIRMLQAIRDSGGGMRSTHSGREN 684
Fly 685 VVATRFAIIVTTDCACWLPIIVVKLAAL--------SGCEISPDLYAWLAVLVLPVNSALNPVLY 741
Fly 742 TLTTAAFKQ-------------------QLRRYCHTLPSCSLVNNETRSQTQ 774 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Lgr4 | NP_001285192.1 | Ldl_recept_a | 87..124 | CDD:278486 | |
| LRR_RI | <184..397 | CDD:238064 | 65/319 (20%) | ||
| LRR_8 | 188..248 | CDD:290566 | 16/67 (24%) | ||
| leucine-rich repeat | 188..211 | CDD:275380 | 8/22 (36%) | ||
| leucine-rich repeat | 212..235 | CDD:275380 | 4/23 (17%) | ||
| leucine-rich repeat | 238..261 | CDD:275380 | 7/33 (21%) | ||
| LRR_8 | 261..320 | CDD:290566 | 14/67 (21%) | ||
| leucine-rich repeat | 262..285 | CDD:275380 | 5/30 (17%) | ||
| LRR_4 | 284..325 | CDD:289563 | 10/41 (24%) | ||
| leucine-rich repeat | 286..309 | CDD:275380 | 4/22 (18%) | ||
| LRR_4 | 308..348 | CDD:289563 | 15/53 (28%) | ||
| leucine-rich repeat | 310..334 | CDD:275380 | 12/30 (40%) | ||
| leucine-rich repeat | 335..357 | CDD:275380 | 6/28 (21%) | ||
| LRR_8 | 356..416 | CDD:290566 | 20/125 (16%) | ||
| leucine-rich repeat | 358..381 | CDD:275380 | 8/37 (22%) | ||
| LRR_4 | 381..421 | CDD:289563 | 12/86 (14%) | ||
| leucine-rich repeat | 382..405 | CDD:275380 | 8/69 (12%) | ||
| leucine-rich repeat | 406..427 | CDD:275380 | 4/20 (20%) | ||
| 7tm_1 | 483..741 | CDD:278431 | 74/268 (28%) | ||
| Tshr | NP_037020.2 | leucine-rich repeat | 54..77 | CDD:275380 | 8/22 (36%) |
| LRR_5 | 65..221 | CDD:404228 | 35/156 (22%) | ||
| leucine-rich repeat | 78..102 | CDD:275380 | 4/23 (17%) | ||
| LRR 1 | 100..124 | 5/23 (22%) | |||
| leucine-rich repeat | 103..127 | CDD:275380 | 5/23 (22%) | ||
| LRR 2 | 125..150 | 4/24 (17%) | |||
| leucine-rich repeat | 128..177 | CDD:275380 | 7/48 (15%) | ||
| LRR 3 | 151..174 | 4/22 (18%) | |||
| LRR 4 | 176..199 | 4/23 (17%) | |||
| leucine-rich repeat | 180..201 | CDD:275380 | 4/21 (19%) | ||
| LRR 5 | 201..223 | 9/21 (43%) | |||
| leucine-rich repeat | 202..229 | CDD:275380 | 10/27 (37%) | ||
| LRR 6 | 225..248 | 5/23 (22%) | |||
| leucine-rich repeat | 230..251 | CDD:275380 | 3/20 (15%) | ||
| LRR 7 | 264..288 | 5/23 (22%) | |||
| 7tmA_TSH-R | 415..689 | CDD:320630 | 84/295 (28%) | ||
| TM helix 1 | 417..441 | CDD:320630 | 9/23 (39%) | ||
| TM helix 2 | 450..471 | CDD:320630 | 10/21 (48%) | ||
| TM helix 3 | 495..517 | CDD:320630 | 7/21 (33%) | ||
| TM helix 4 | 540..556 | CDD:320630 | 4/15 (27%) | ||
| TM helix 5 | 580..603 | CDD:320630 | 6/25 (24%) | ||
| TM helix 6 | 623..645 | CDD:320630 | 8/21 (38%) | ||
| TM helix 7 | 657..682 | CDD:320630 | 11/31 (35%) | ||
| PDZ-binding | 762..764 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_KOG2087 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 1 | 1.000 | - | - | ||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| 3 | 2.810 | |||||