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Protein Alignment Lgr4 and tmtops3a

DIOPT Version :10

Sequence 1:	NP_001285192.1	Gene:	Lgr4 / 5740505	FlyBaseID:	FBgn0085440	Length:	809	Species:	Drosophila melanogaster
Sequence 2:	NP_001269303.1	Gene:	tmtops3a / 102031125	ZFINID:	ZDB-GENE-130828-1	Length:	379	Species:	Danio rerio

Alignment Length:	372	Identity:	91/372 - (24%)
Similarity:	148/372 - (39%)	Gaps:	85/372 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   426 NLTSLDYIYFSWFHLCSAAMNVR-------VCDPHGD--GISSKLHLLDNQILRGSVWVMASIAV 481
            |::|.|          ::|:|..       :.:||..  |:|...|.: ..:..|::.::..:
Zfish     9 NISSKD----------TSALNQSGNVSSGDLLEPHDSPPGLSRTGHTV-TAVCLGAILLLGCL-- 60

  Fly   482 VGNLLVLLGRYFYKSRSN-VEHSLYLRHLAASDFLMGIYLTLIACADISFRGEYIKYEETWRHSG 545
             .||.|||  .|.:.||. ...:|.|.:::.||.|:.::.|..:.|. |..|:::     ..|.|
Zfish    61 -NNLFVLL--VFARFRSLWTPINLILLNISVSDILVCLFGTPFSFAS-SLYGKWL-----LGHHG 116

  Fly   546 VCAFAGFLSTFSCQSSTLLLTLVTWDRLMSVTRPLKPRDTEKVRIVLRLL------LLWGISFGL 604
             |.:.||.::.....|.:.|::::::|..::.|..|...::..|..|.:.      |||
Zfish   117 -CKWYGFANSLFGIVSLMSLSILSYERYAALLRATKADVSDFRRAWLCVAGSWLYSLLW------ 174

  Fly   605 AAAPLLPNPYFGSHFYGNNG---VCLSLHIHDPYAKGWEYSALLFILVNTLSLIFILFSYIRMLQ 666
                .|| |:.|...||..|   .| |:..|........|...|||....|.|:.::|.|.::|.
Zfish   175 ----TLP-PFLGWSNYGPEGPGTTC-SVQWHLRSTSSISYVMCLFIFCLLLPLVLMIFCYGKILL 233

  Fly   667 AIRDSGGGMRSTHSGRENVVATRFAIIVTTDCACWLPIIVVKLAALSGCEISPDLYAWLAVLVLP 731
            .|:........|...|||.:......:|:....||:|..||.|.|..|          ...|:.|
Zfish   234 LIKGVTKINLLTAQRRENHILLMVVTMVSCYLLCWMPYGVVALLATFG----------RTGLITP 288

  Fly   732 VNS-----------ALNPVLYTLTTAAFKQQLRR------YCHTLPS 761
            |.|           .:|||:|.|    |..|..|      .|...||
Zfish   289 VTSIVPSVLAKSSTVVNPVIYVL----FNNQFYRCFVAFLKCQGEPS 331

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.