DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG34430 and TMBIM1

DIOPT Version :9

Sequence 1:NP_001097222.1 Gene:CG34430 / 5740489 FlyBaseID:FBgn0085459 Length:264 Species:Drosophila melanogaster
Sequence 2:NP_001308356.1 Gene:TMBIM1 / 64114 HGNCID:23410 Length:311 Species:Homo sapiens


Alignment Length:223 Identity:53/223 - (23%)
Similarity:97/223 - (43%) Gaps:37/223 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly    33 EFDIADVGIRRRLVRRFYGILILQMACTLPCIELFLKYPLPYNFVMPLS-----------MVFTV 86
            |:|  |..:|...:|:.|.|:.:|:..|:..|.:|       .||.|:|           :.:.|
Human    88 EWD--DRKVRHTFIRKVYSIISVQLLITVAIIAIF-------TFVEPVSAFVRRNVAVYYVSYAV 143

  Fly    87 FL--YTCFYVWRDWRRHGPFNYFVLLLSTLIGSFNRSVYLLNLVETHWVYIYPVILIIEILGLML 149
            |:  |......:..||..|:|..:|.|.|....|.... :.::.:|..|.|..:|..:..:.:.:
Human   144 FVVTYLILACCQGPRRRFPWNIILLTLFTFAMGFMTGT-ISSMYQTKAVIIAMIITAVVSISVTI 207

  Fly   150 YSSQKRFRFTQIRG----ISIISLIFG------LFLLLAYRLNRMMEVFSAMACTVEAWYIIYDT 204
            :..|.:..||...|    :.|:.|:.|      |:....|.|:.:.....|:..|:   ::.|||
Human   208 FCFQTKVDFTSCTGLFCVLGIVLLVTGIVTSIVLYFQYVYWLHMLYAALGAICFTL---FLAYDT 269

  Fly   205 HYMLCGRHGYNIGPEEFVYAACNIHCDL 232
            ..:| |...:.|.||:::..|..|:.|:
Human   270 QLVL-GNRKHTISPEDYITGALQIYTDI 296

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG34430NP_001097222.1 BI-1-like 41..231 CDD:294323 49/212 (23%)
TMBIM1NP_001308356.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..37
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 50..72
LFG_like 89..308 CDD:198410 52/222 (23%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0670
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1290306at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.910

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