Protein Alignment CG34430 and TMBIM4

DIOPT Version :10

• Sequence 1: NP_001097222.1
• Gene: CG34430 / 5740489
• FlyBaseID: FBgn0085459
• Length: 264
• Species: Drosophila melanogaster
• Sequence 2: NP_001269535.1
• Gene: TMBIM4 / 51643
• HGNCID: 24257
• Length: 285
• Species: Homo sapiens
• Alignment Length: 232
• Identity: 58/232 - (25%)
• Similarity: 100/232 - (43%)
• Gaps: 56/232 - (24%)

  Fly    46 VRRFYGILILQMACTLPCIELFLKYPLPYNFVM------------PLSMVFTVFLYTCFYVWRDW 98
            :|:.|.||.||:..|.....:||.:.....||.            .|.::|.:.|
Human    82 LRKVYSILSLQVLLTTVTSTVFLYFESVRTFVHESPALILLFALGSLGLIFALIL---------- 136

  Fly    99 RRHG-PFNYFVLLLSTLIGSFNRSVYLLNLVETHWVYIYPVILIIE--------ILGLMLYSSQK 154
            .||. |.|.::|...||:.:...:|.         |..|.|.:|::        ..||.:|:.|.
Human   137 NRHKYPLNLYLLFGFTLLEALTVAVV---------VTFYDVYIILQAFILTTTVFFGLTVYTLQS 192

  Fly   155 RFRFTQIRGISIISLIFGLFL---LLAYRLNRMME-VFSAMACTVEAWYIIYDTHYMLCGRHGYN 215
            :..|::. |..:.:|::.|.|   |..:..:.:|| |.:|....:...:||||||.::     :.
Human   193 KKDFSKF-GAGLFALLWILCLSGFLKFFFYSEIMELVLAAAGALLFCGFIIYDTHSLM-----HK 251

  Fly   216 IGPEEFVYAACNIHCDLPKGMWRLMKMLFFSKIVEAV 252
            :.|||:|.||.:::.|:......|::.|      |||
Human   252 LSPEEYVLAAISLYLDIINLFLHLLRFL------EAV 282

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG34430	NP_001097222.1	BI-1-like	41..231	CDD:469783	52/209 (25%)
TMBIM4	NP_001269535.1	GAAP_like	6..283	CDD:198411	58/232 (25%)