DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34430 and tmbim1a

DIOPT Version :9

Sequence 1:	NP_001097222.1	Gene:	CG34430 / 5740489	FlyBaseID:	FBgn0085459	Length:	264	Species:	Drosophila melanogaster
Sequence 2:	NP_001005992.2	Gene:	tmbim1a / 449819	ZFINID:	ZDB-GENE-041010-69	Length:	332	Species:	Danio rerio

Alignment Length:	268	Identity:	61/268 - (22%)
Similarity:	117/268 - (43%)	Gaps:	44/268 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 AVLVVEKSEVPGIAVQCDLLLPNGHLQRTYEFDIADVGIRRRLVRRFYGILILQMACTLPCIELF 67
            |:.|:.....|||..........|       |:..||  |...:|:.|.||..|:..|...:.:|
Zfish    85 AMPVIPVMPPPGIGDSEGFTTAEG-------FESTDV--RHSFIRKVYLILAAQLLVTAAVVAIF 140

  Fly    68 L----------KYPLPYNFVMPLSMVFTVFLYTCFYVWRDWRRHGPFNYFVLLLSTLIGSF---N 119
            .          |.|..|.....:..|..:.|..|    :..||..|:|..:|.:.||..||   |
Zfish   141 TFVEPVGLFVRKNPAIYWVSYAIYFVTHIVLVCC----QGPRRRFPWNLLLLAIFTLALSFMTGN 201

  Fly   120 RSVYLLNLVETHWVYIYPVILIIEILGLMLYSSQKRFRFTQIRG----ISIISLIFGLF--LLLA 178
            .:.|    ..|..|::...|.::..:.:.::..|.:..||:..|    :.|:..:.|:.  ::|:
Zfish   202 IASY----YSTRAVFLALAITVVVCVAVTVFCFQTKVDFTKCSGFFCVLGIVVFVTGIITAIVLS 262

  Fly   179 YR----LNRMMEVFSAMACTVEAWYIIYDTHYMLCGRHGYNIGPEEFVYAACNIHCDLPKGMWRL 239
            ::    |:.:.....|:|.|:   ::.|.|. :|.|....:|.|||:|:||.:::.|:.:....|
Zfish   263 FKYVPWLHMLYASIGAIAFTL---FLAYHTQ-LLIGNRKLSISPEEYVFAALSLYVDIVQIFIFL 323

  Fly   240 MKMLFFSK 247
            ::::.:::
Zfish   324 LQIIGYAE 331

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34430	NP_001097222.1	BI-1-like	41..231	CDD:294323	50/212 (24%)
tmbim1a	NP_001005992.2	ARS2	<21..83	CDD:282772
tmbim1a	NP_001005992.2	LFG_like	108..328	CDD:198410	56/240 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0670
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1290306at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910