DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34430 and Tmbim7

DIOPT Version :9

Sequence 1:	NP_001097222.1	Gene:	CG34430 / 5740489	FlyBaseID:	FBgn0085459	Length:	264	Species:	Drosophila melanogaster
Sequence 2:	NP_001034701.2	Gene:	Tmbim7 / 362319	RGDID:	1306626	Length:	303	Species:	Rattus norvegicus

Alignment Length:	242	Identity:	66/242 - (27%)
Similarity:	114/242 - (47%)	Gaps:	42/242 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 AVQC--DLLLPNGHLQRTYEFDIADVGIRRRLVRRFYGILILQMACTLPCIELF----------L 68
            |||.  |...||..:..:..|:  :..||:..:.:.:.:|..|:..|...|.:|          :
  Rat    66 AVQISEDATPPNESVNLSGPFE--NTSIRKGFIVKVFVVLSAQLLITAAIISIFVFCEAVRKWII 128

  Fly    69 KYPLPYNFVMPLSMVFTVFLYTCFYVWRDWRRHGPFNYFVLLLST-----LIGSFNRSVYLLNLV 128
            ..|.....::|..::..|.|..|    ||.||..|.||.:|:..|     |:||.  ||: ....
  Rat   129 AMPWFMYALLPAVLIVIVILACC----RDIRRQVPANYILLVFFTILEGLLLGSM--SVF-YKAD 186

  Fly   129 ETHWV--YIYPVILIIEILGLMLYSSQKRFRFTQIRGI----SIISLIFGLFLLL--AYRLNRMM 185
            |..|.  ....|.|:     |.|::.|.::.||.:.|:    :.:.:|:|:..|:  :|.|:.
  Rat   187 EILWATGATTAVTLV-----LTLFALQTKWDFTLLNGMLFVFTSVLVIYGIVTLVVRSYWLHL-- 244

  Fly   186 EVFSAMACTVEAWYIIYDTHYMLCGRHGYNIGPEEFVYAACNIHCDL 232
             |:||:...:.:.|::.|...|:.||:.|.|.|||:::||.||:.|:
  Rat   245 -VYSALGTLLFSMYLVMDVQMMVGGRYHYEIDPEEYIFAALNIYVDI 290

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34430	NP_001097222.1	BI-1-like	41..231	CDD:294323	58/212 (27%)
Tmbim7	NP_001034701.2	LFG_like	85..302	CDD:198410	60/223 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0670
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1290306at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910