DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34430 and GRINA

DIOPT Version :9

Sequence 1:	NP_001097222.1	Gene:	CG34430 / 5740489	FlyBaseID:	FBgn0085459	Length:	264	Species:	Drosophila melanogaster
Sequence 2:	NP_000828.1	Gene:	GRINA / 2907	HGNCID:	4589	Length:	371	Species:	Homo sapiens

Alignment Length:	214	Identity:	54/214 - (25%)
Similarity:	109/214 - (50%)	Gaps:	31/214 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 DVGIRRRLVRRFYGILILQMACTLPCIELFLKYPLPYNFVMPLSMVFTVFL-YTCFYV------- 94
            |..||:..:|:.:.:|.||::.||..:.:|........||.  ..|:|.:: |..|::
Human   154 DKSIRQAFIRKVFLVLTLQLSVTLSTVSVFTFVAEVKGFVR--ENVWTYYVSYAVFFISLIVLSC 216

  Fly    95 WRDWRRHGPFNYFVLLLSTLIGSFNRSVYLLNLVETHWVYIYPVILIIEILGL--------MLYS 151
            ..|:||..|:|  ::.||.|..|.:   |::.::.:    .|....:|..:|:        :::|
Human   217 CGDFRRKHPWN--LVALSVLTASLS---YMVGMIAS----FYNTEAVIMAVGITTAVCFTVVIFS 272

  Fly   152 SQKRFRFTQIRGISIISLI--FGLFLLLAYRLNRMME-VFSAMACTVEAWYIIYDTHYMLCGRHG 213
            .|.|:.||...|:.::|::  |...:|..:..||::| |::::...:...::..||. :|.|...
Human   273 MQTRYDFTSCMGVLLVSMVVLFIFAILCIFIRNRILEIVYASLGALLFTCFLAVDTQ-LLLGNKQ 336

  Fly   214 YNIGPEEFVYAACNIHCDL 232
            .::.|||:|:||.|::.|:
Human   337 LSLSPEEYVFAALNLYTDI 355

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34430	NP_001097222.1	BI-1-like	41..231	CDD:294323	52/208 (25%)
GRINA	NP_000828.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..145
		Pro-rich	<43..139	CDD:373673
		LFG_like	151..367	CDD:198410	54/214 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0670
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1290306at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.910