DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34430 and FAIM2

DIOPT Version :9

Sequence 1:	NP_001097222.1	Gene:	CG34430 / 5740489	FlyBaseID:	FBgn0085459	Length:	264	Species:	Drosophila melanogaster
Sequence 2:	NP_036438.2	Gene:	FAIM2 / 23017	HGNCID:	17067	Length:	316	Species:	Homo sapiens

Alignment Length:	247	Identity:	65/247 - (26%)
Similarity:	110/247 - (44%)	Gaps:	43/247 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 PGIAVQCDLLLPNG--HLQRTYEFDIADVGIRRRLVRRFYGILILQMACTLPCIELFLKYPLPYN 75
            |..:...|...|.|  .|..|:.:|  |..:||..||:.|.||::|:..||..:.||       .
Human    70 PSSSSSYDNGFPTGDHELFTTFSWD--DQKVRRVFVRKVYTILLIQLLVTLAVVALF-------T 125

  Fly    76 FVMPLS-----------MVFTVFL--YTCFYVWRDWRRHGPFNYFVLLLSTLIGSFNRSVYLLNL 127
            |..|:.           ..:.||.  |.........|||.|:|..:|.:.||     ...||..:
Human   126 FCDPVKDYVQANPGWYWASYAVFFATYLTLACCSGPRRHFPWNLILLTVFTL-----SMAYLTGM 185

  Fly   128 VETHW----VYIYPVILIIEILGLMLYSSQKRFRFTQIRGISIISLIFGLF---LLLAYRL---- 181
            :.:::    |.:...|..:..|.:.::|.|.:|.||..:|:..: |:..||   |:||..|
Human   186 LSSYYNTTSVLLCLGITALVCLSVTVFSFQTKFDFTSCQGVLFV-LLMTLFFSGLILAILLPFQY 249

  Fly   182 -NRMMEVFSAMACTVEAWYIIYDTHYMLCGRHGYNIGPEEFVYAACNIHCDL 232
             ..:..|::|:...|...::..||. :|.|...:::.|||:::.|.||:.|:
Human   250 VPWLHAVYAALGAGVFTLFLALDTQ-LLMGNRRHSLSPEEYIFGALNIYLDI 300

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34430	NP_001097222.1	BI-1-like	41..231	CDD:294323	56/214 (26%)
FAIM2	NP_036438.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..53
FAIM2	NP_036438.2	LFG_like	92..312	CDD:198410	59/225 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0670
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1290306at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.910