DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fili and RLP15

DIOPT Version :9

Sequence 1:	NP_001369108.1	Gene:	Fili / 5740472	FlyBaseID:	FBgn0085397	Length:	789	Species:	Drosophila melanogaster
Sequence 2:	NP_177559.1	Gene:	RLP15 / 843759	AraportID:	AT1G74190	Length:	965	Species:	Arabidopsis thaliana

Alignment Length:	592	Identity:	136/592 - (22%)
Similarity:	214/592 - (36%)	Gaps:	205/592 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 ILPP---ETTAFCPSKCQCLGGEANSRALCV-----------DAALEDVPIQLNP--ETKYINLT 81
            :||.   :||:.|   |:..|...|..:..|           |.:|.::.: |:|  :.:.:||:
plant    51 VLPTWTNDTTSDC---CRWKGVACNRVSGRVTEISFGGLSLKDNSLLNLSL-LHPFEDVRSLNLS 111

  Fly    82 VNRIRTLEFSLPFY------MKLEILDLSQNIIETLGSKNFEYQS---ELRTLNL-SRNLVSSLH 136
            .:|...|...:..|      .|||||||:.|   ...:..|.:.|   .|.||.| |.|:..|..
plant   112 SSRCSGLFDDVEGYKSLRKLRKLEILDLASN---KFNNSIFHFLSAATSLTTLFLRSNNMDGSFP 173

  Fly   137 KHAFKGLTNLLLLDLSFNRIETVHP---------------------------------------T 162
            ....:.||||.|||||.||.....|                                       :
plant   174 AKELRDLTNLELLDLSRNRFNGSIPIQELSSLRKLKALDLSGNEFSGSMELQGKFCTDLLFSIQS 238

  Fly   163 ALSDLASLVELDLTNNNIVSLEDNCFKGMNTLEVLVFRNNRLLDVPASNLWHLHALKSLDMSLNL 227
            .:.:|.::.||||:.|.:|....:|...:..|.||...:|:|.....|:|..|.:|:.|.:..|
plant   239 GICELNNMQELDLSQNKLVGHLPSCLTSLTGLRVLDLSSNKLTGTVPSSLGSLQSLEYLSLFDN- 302

  Fly   228 VEFVRNDSFEGLKEL-----LALSVQGNVMSELDLSAFE-----GLIS----------------- 265
             :|..:.||..|..|     |.|..:.:.:..|..|:::     .:|:
plant   303 -DFEGSFSFGSLANLSNLMVLKLCSKSSSLQVLSESSWKPKFQLSVIALRSCNMEKVPHFLLHQK 366

  Fly   266 -LKHLDLSDNNLT-MVPTQQLSKLSNLTYLNLGGNRFS--QLPAVA------------FLNLF-- 312
             |:|:||||||:: .:|:..|:..:.|..|.|..|.|:  |:|..|            |.:||
plant   367 DLRHVDLSDNNISGKLPSWLLANNTKLKVLLLQNNLFTSFQIPKSAHNLLFLDVSANDFNHLFPE 431

  Fly   313 -------HLRELHLSRLDFLQRIDSRAFVDNTHLQTLHLNNNPQLSDIPMRLFQGN--------- 361
                   |||.|:.|:.:|.:.:.|          :|...|..|..|:....|.||
plant   432 NIGWIFPHLRYLNTSKNNFQENLPS----------SLGNMNGIQYMDLSRNSFHGNLPRSFVNGC 486

  Fly   362 ------------------------PNILEVYMQSN--------SLQTLYSAQF------------ 382
                                    .|||.::|.:|        .|::|.:.:.
plant   487 YSMAILKLSHNKLSGEIFPESTNFTNILGLFMDNNLFTGKIGQGLRSLINLELLDMSNNNLTGVI 551

  Fly   383 -----PVDQLQKLYLGDNPLQ-------CNCSLLWLWRLVTGNFEGVDPGMEHAAGGAVAALAKE 435
                 .:..|..|.:.||.|:       .|.|.|.|..|...:..||.|....:..|.|..|
plant   552 PSWIGELPSLTALLISDNFLKGDIPMSLFNKSSLQLLDLSANSLSGVIPPQHDSRNGVVLLL--- 613

  Fly   436 ADDEELA 442
             .|.:|:
plant   614 -QDNKLS 619

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fili	NP_001369108.1	leucine-rich repeat	75..97	CDD:275378	5/27 (19%)
		leucine-rich repeat	98..121	CDD:275380	9/25 (36%)
		LRR_8	120..180	CDD:404697	26/102 (25%)
		leucine-rich repeat	122..145	CDD:275380	8/23 (35%)
		leucine-rich repeat	146..169	CDD:275380	10/61 (16%)
		LRR	<161..>354	CDD:227223	62/283 (22%)
		leucine-rich repeat	170..193	CDD:275380	7/22 (32%)
		leucine-rich repeat	194..217	CDD:275380	8/22 (36%)
		leucine-rich repeat	218..265	CDD:275380	12/56 (21%)
		leucine-rich repeat	266..289	CDD:275380	10/23 (43%)
		leucine-rich repeat	290..313	CDD:275380	11/45 (24%)
		leucine-rich repeat	314..338	CDD:275380	6/23 (26%)
		LRR_8	337..397	CDD:404697	18/117 (15%)
		leucine-rich repeat	339..360	CDD:275380	5/20 (25%)
RLP15	NP_177559.1	LRRNT_2	28..72	CDD:369783	7/23 (30%)
		PLN00113	<105..>287	CDD:215061	47/184 (26%)
		leucine-rich repeat	106..133	CDD:275380	5/26 (19%)
		leucine-rich repeat	134..157	CDD:275380	9/25 (36%)
		leucine-rich repeat	158..182	CDD:275380	8/23 (35%)
		leucine-rich repeat	183..207	CDD:275380	9/23 (39%)
		leucine-rich repeat	208..245	CDD:275380	1/36 (3%)
		leucine-rich repeat	246..269	CDD:275380	7/22 (32%)
		PLN00113	249..>892	CDD:215061	87/387 (22%)
		leucine-rich repeat	270..293	CDD:275380	8/22 (36%)
		leucine-rich repeat	294..318	CDD:275380	8/25 (32%)
		leucine-rich repeat	319..357	CDD:275380	5/37 (14%)
		leucine-rich repeat	368..392	CDD:275380	10/23 (43%)
		leucine-rich repeat	440..463	CDD:275380	7/32 (22%)
		leucine-rich repeat	465..488	CDD:275380	5/22 (23%)
		leucine-rich repeat	489..512	CDD:275380	0/22 (0%)
		leucine-rich repeat	513..536	CDD:275380	6/22 (27%)
		leucine-rich repeat	537..560	CDD:275380	0/22 (0%)
		leucine-rich repeat	561..584	CDD:275380	6/22 (27%)
		leucine-rich repeat	585..607	CDD:275380	6/21 (29%)
		leucine-rich repeat	608..629	CDD:275380	5/16 (31%)
		leucine-rich repeat	630..652	CDD:275380
		leucine-rich repeat	653..676	CDD:275380
		leucine-rich repeat	677..697	CDD:275380
		leucine-rich repeat	744..804	CDD:275380
		leucine-rich repeat	749..780	CDD:275380
		leucine-rich repeat	805..828	CDD:275380
		leucine-rich repeat	829..850	CDD:275380
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000