DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Fili and RLP12

DIOPT Version :9

Sequence 1:	NP_001369108.1	Gene:	Fili / 5740472	FlyBaseID:	FBgn0085397	Length:	789	Species:	Drosophila melanogaster
Sequence 2:	NP_177296.2	Gene:	RLP12 / 843481	AraportID:	AT1G71400	Length:	847	Species:	Arabidopsis thaliana

Alignment Length:	432	Identity:	99/432 - (22%)
Similarity:	159/432 - (36%)	Gaps:	134/432 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 GAIPVLLLLLLTLVILPPETTAFCPSKCQCLGGEANSRALCVDAALEDVPIQLNPETKYINLTVN 83
            |.:|..|..|.|:|:.....::|          |..|:.   :|.:|::.:..|.....|...:.
plant   413 GEVPACLWRLNTMVLSHNSFSSF----------ENTSQE---EALIEELDLNSNSFQGPIPYMIC 464

  Fly    84 RIRTLEFSLPFYMKLEILDLSQNIIETLGS-----KNFEYQSELRTLNLSRNLVSSLHKHAFKGL 143
            ::.:|.|          ||||.|:..  ||     :||  ...::.|||..|..|......|...
plant   465 KLSSLGF----------LDLSNNLFS--GSIPSCIRNF--SGSIKELNLGDNNFSGTLPDIFSKA 515

  Fly   144 TNLLLLDLSFNRIETVHPTALSDLASLVELDLTNNNIVSLEDNCFKGMNTLEVLVFRNN------ 202
            |.|:.||:|.|::|...|.:|.:..:|..:::.:|.|..:..:..:.:.:|.||..|:|
plant   516 TELVSLDVSHNQLEGKFPKSLINCKALELVNVESNKIKDIFPSWLESLPSLHVLNLRSNKFYGPL 580

  Fly   203 ------------RLLDVPASN-----------------------------LW-----HLHAL--- 218
                        |::|:..:|                             .|     :.|.:
plant   581 YHRHASIGFQSLRIIDISHNNFSGTLPPYYFSNWKDMTTLTEEMDQYMTEFWRYADSYYHEMEMV 645

  Fly   219 -KSLDMSLNLVEFVRND----SFEG-------------LKELLALSVQGNVMSELDLSAFEGLIS 265
             |.:|||.   |.:|.|    .|.|             ||||..|::.||..:.:.......|..
plant   646 NKGVDMSF---ERIRRDFRAIDFSGNKINGNIPESLGYLKELRVLNLSGNAFTSVIPRFLANLTK 707

  Fly   266 LKHLDLSDNNLTMVPTQQLSKLSNLTYLNLGGNRFSQLPAVAFLNLFHLRELHLSRLDFLQRIDS 330
            |:.||:|.|.|:....|.|:.||.|:|:|...|               |.:..:.|....||...
plant   708 LETLDISRNKLSGQIPQDLAALSFLSYMNFSHN---------------LLQGPVPRGTQFQRQKC 757

  Fly   331 RAFVDNTHLQTLH--------LNNNPQLSDIPMRLFQGNPNI 364
            .:|:||..|..|.        ||...||   |..|.:...|:
plant   758 SSFLDNPGLYGLEDICRDTGALNPTSQL---PEDLSEAEENM 796

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fili	NP_001369108.1	leucine-rich repeat	75..97	CDD:275378	3/21 (14%)
		leucine-rich repeat	98..121	CDD:275380	9/27 (33%)
		LRR_8	120..180	CDD:404697	17/59 (29%)
		leucine-rich repeat	122..145	CDD:275380	6/22 (27%)
		leucine-rich repeat	146..169	CDD:275380	8/22 (36%)
		LRR	<161..>354	CDD:227223	59/273 (22%)
		leucine-rich repeat	170..193	CDD:275380	3/22 (14%)
		leucine-rich repeat	194..217	CDD:275380	9/74 (12%)
		leucine-rich repeat	218..265	CDD:275380	17/67 (25%)
		leucine-rich repeat	266..289	CDD:275380	9/22 (41%)
		leucine-rich repeat	290..313	CDD:275380	4/22 (18%)
		leucine-rich repeat	314..338	CDD:275380	7/23 (30%)
		LRR_8	337..397	CDD:404697	9/36 (25%)
		leucine-rich repeat	339..360	CDD:275380	8/28 (29%)
RLP12	NP_177296.2	LRRNT_2	36..80	CDD:285463
		LRR_8	112..170	CDD:290566
		leucine-rich repeat	112..135	CDD:275380
		leucine-rich repeat	136..159	CDD:275380
		LRR_8	159..218	CDD:290566
		leucine-rich repeat	160..183	CDD:275380
		leucine-rich repeat	184..207	CDD:275380
		LRR_RI	198..479	CDD:238064	20/88 (23%)
		LRR_8	206..266	CDD:290566
		leucine-rich repeat	208..231	CDD:275380
		leucine-rich repeat	232..255	CDD:275380
		leucine-rich repeat	256..279	CDD:275380
		leucine-rich repeat	280..352	CDD:275380
		leucine-rich repeat	304..322	CDD:275380
		LRR_8	351..411	CDD:290566
		leucine-rich repeat	353..376	CDD:275380
		LRR_RI	374..601	CDD:238064	49/214 (23%)
		leucine-rich repeat	377..400	CDD:275380
		leucine-rich repeat	401..422	CDD:275380	3/8 (38%)
		leucine-rich repeat	445..468	CDD:275380	3/22 (14%)
		leucine-rich repeat	469..493	CDD:275380	11/37 (30%)
		leucine-rich repeat	494..517	CDD:275380	6/22 (27%)
		LRR_8	516..576	CDD:290566	17/59 (29%)
		leucine-rich repeat	518..541	CDD:275380	8/22 (36%)
		leucine-rich repeat	542..565	CDD:275380	3/22 (14%)
		leucine-rich repeat	592..616	CDD:275380	3/23 (13%)
		leucine-rich repeat	617..683	CDD:275380	12/68 (18%)
		LRR_8	682..742	CDD:290566	21/74 (28%)
		LRR_4	682..719	CDD:289563	12/36 (33%)
		leucine-rich repeat	684..707	CDD:275380	5/22 (23%)
		leucine-rich repeat	708..729	CDD:275380	8/20 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000