Protein Alignment Fili and zgc:153913

DIOPT Version :10

• Sequence 1: NP_001369108.1
• Gene: Fili / 5740472
• FlyBaseID: FBgn0085397
• Length: 789
• Species: Drosophila melanogaster
• Sequence 2: NP_001073448.1
• Gene: zgc:153913 / 559700
• ZFINID: ZDB-GENE-061103-397
• Length: 496
• Species: Danio rerio
• Alignment Length: 553
• Identity: 134/553 - (24%)
• Similarity: 220/553 - (39%)
• Gaps: 126/553 - (22%)

  Fly    17 LCGAIPVLLLLLLTLVILPPETTAFCPSKCQCLGGEANSRALCVDAALEDVPIQLNPETKYINLT 81
            ||.   |:||:|:.|.     ....||..|||..|   |:.:|.|..::.:|:.::.:.:.:.:.
Zfish     4 LCA---VVLLVLIHLY-----CGVCCPEPCQCFSG---SKLVCSDDRMKSLPVNISTQVRELIVV 57

  Fly    82 VNRIRTL-EFSLPFYMKLEILDLSQNIIETLGSKNFEYQSELRTLNLSRNLV-SSLHKHAFKGLT 144
            .:.|..| :.|.|..::|..|.....:::::..:.||...|||.|.:|.|:. .||....|..||
Zfish    58 ASGIPDLDQQSFPETLRLSKLVFLNGMLKSVSGEAFERLVELRELEISGNICWMSLDIQTFSSLT 122

  Fly   145 NLLLLDLSFNRIETV----------------HPTALSDLAS--------LVELDLTNNNIVSLED 185
            ||..|.|:.|::..|                ....||.|:.        |.||||:.|.|.||..
Zfish   123 NLTRLLLNNNKLSGVDAGLFHSLHQLEMLQLRGNGLSFLSGRLFQRLHRLQELDLSFNQISSLST 187

  Fly   186 NCFKGMNTLEVLVFRNNRLLDVPASNLWHLHALKSLDMSLNLVEFVRNDSFEGLKELLALSVQGN 250
            ..|:..:.|.||..:.|::.::|.....||..|:.|::..||:..:...||..  .|..|.::.|
Zfish   188 ELFQNNSELRVLSLQANKIPNLPDGIFTHLDHLQELNLRSNLIRVLTPGSFPA--SLKTLILKKN 250

  Fly   251 VMSELDLSAFEGLISLKHLDLSDNNLTMVPTQQLSKLSNLTYLNLGGNRFSQLPAVAFLNLFHLR 315
            ::.:|..:.|..|..:.:||||.|:||.||......|.:|..|:|..||.|.|....|..||.::
Zfish   251 LLEKLTNAVFHTLHYITYLDLSQNSLTEVPADLFQNLISLETLDLSENRISTLAGSVFKGLFSIK 315

  Fly   316 ELHLSRLDFLQRIDSRAFVDNTHLQTLHLNNNPQLSDIPMRLFQGNPNILEVYMQSNSLQTLYSA 380
            .::|.: :.|..:|:....|...||.|.|:|| .|..||...|           :....|.::.
Zfish   316 SVYLQK-NSLISVDAHLLKDQHDLQLLDLSNN-SLRSIPSGFF-----------EDLDFQCVFE- 366

  Fly   381 QFPVDQLQKLYLGDNPLQCNCSLLWLWRLVTGNFEGVDPGMEHAAGGAVAALAKEADDEELADEA 445
                       |..||..|:|.:.:.:..:..|
Zfish   367 -----------LRGNPWSCDCGIHYFYDWLKYN-------------------------------- 388

  Fly   446 TAVASTDDGVAALAAYIAEQHIVNALHTTEPSAYELATSSSNRNSGILRMDRQQIGCDIWRDKVR 510
                              .:| |..|......|.||....:.|:     :||:|:.|.  |:...
Zfish   389 ------------------HKH-VKDLSRVSCEAPELIQGHNLRS-----VDREQLVCS--RNSSS 427

  Fly   511 TRRKLLTMSEGEITCPAH----IVTVVCAVITC 539
            ...:::::.||.|.|...    ..::.|.|..|
Zfish   428 NSPEMISVDEGSIQCSVQELKGTASIECKVTKC 460

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fili	NP_001369108.1	LRR	71..>348	CDD:443914	86/302 (28%)
		leucine-rich repeat	75..97	CDD:275378	4/22 (18%)
		leucine-rich repeat	98..121	CDD:275380	4/22 (18%)
		leucine-rich repeat	122..145	CDD:275380	9/23 (39%)
		leucine-rich repeat	146..169	CDD:275380	8/38 (21%)
		leucine-rich repeat	170..193	CDD:275380	10/22 (45%)
		leucine-rich repeat	194..217	CDD:275380	7/22 (32%)
		leucine-rich repeat	218..265	CDD:275380	12/46 (26%)
		leucine-rich repeat	266..289	CDD:275380	10/22 (45%)
		leucine-rich repeat	290..313	CDD:275380	9/22 (41%)
		leucine-rich repeat	314..338	CDD:275380	4/23 (17%)
		LRR_8	337..397	CDD:404697	13/59 (22%)
		leucine-rich repeat	339..360	CDD:275380	10/20 (50%)
zgc:153913	NP_001073448.1	leucine-rich repeat	75..98	CDD:275380	4/22 (18%)
		LRR	<142..>352	CDD:443914	63/213 (30%)
		leucine-rich repeat	148..171	CDD:275380	3/22 (14%)
		leucine-rich repeat	172..195	CDD:275380	10/22 (45%)
		leucine-rich repeat	196..219	CDD:275380	7/22 (32%)
		leucine-rich repeat	220..241	CDD:275380	6/22 (27%)
		leucine-rich repeat	242..265	CDD:275380	6/22 (27%)
		leucine-rich repeat	266..289	CDD:275380	10/22 (45%)
		leucine-rich repeat	290..313	CDD:275380	9/22 (41%)
		leucine-rich repeat	314..337	CDD:275380	4/23 (17%)
		leucine-rich repeat	338..359	CDD:275380	10/32 (31%)
		PCC	342..>427	CDD:188093	26/166 (16%)