Protein Alignment Fili and trn

DIOPT Version :9

• Sequence 1: NP_001369108.1
• Gene: Fili / 5740472
• FlyBaseID: FBgn0085397
• Length: 789
• Species: Drosophila melanogaster
• Sequence 2: NP_001261796.1
• Gene: trn / 39491
• FlyBaseID: FBgn0010452
• Length: 751
• Species: Drosophila melanogaster
• Alignment Length: 838
• Identity: 202/838 - (24%)
• Similarity: 337/838 - (40%)
• Gaps: 206/838 - (24%)

  Fly    27 LLLTLVILPPETTAFCPSKCQCLGGEANSRAL-CVDAALEDVPIQLNPETKYINLTVNRIRTLEF 90
            :|.::.:.|....|.||..|||   :.|:..: |.:..|:.:||.|||..:.:.:..|:|:|::.
  Fly    15 ILASIGVEPAAGLANCPPGCQC---DDNTLVVQCGEGQLDVLPIALNPSIQRLVIKSNKIKTIDS 76

  Fly    91 SLPFYMKLEILDLSQNIIETLGSKNFEYQSELRTLNLSRNLVSSLHKHAFKGLTNLLLLDLSFNR 155
            |:.||.:|..||||.|.:.|:..:.|.||.:|:.::|:.|.:..:....|.||:.:.:|:|..|:
  Fly    77 SIQFYAELTFLDLSSNHLMTIPQRTFAYQKKLQEVHLNHNKIGQISNKTFIGLSAVTVLNLRGNQ 141

  Fly   156 IETVHPTALSDLASLVELDLTNNNIVSLEDNCFKGMNTLEVLVFRNNRLLDVPASNLWH-LHALK 219
            |..:|....:.|..:.||:|..|.|..|:...|.|::.|.:|...:|.|..||...::. :.:|.
  Fly   142 ISELHQGTFTPLLKIEELNLGENRIGYLDPKAFDGLSQLRILYLDDNALTTVPDPVIFQAMPSLA 206

  Fly   220 SLDMSLNLVEFVRNDSFEGLKELLALSVQGNVMSELDLSAFEGLISLKHLDLSDNNLTMVPTQQL 284
            .|.:.:|.::.::.|:|:.||.|..|.::|..:..:...:|.||..|:.||||||.|..:|:..|
  Fly   207 ELFLGMNTLQSIQADAFQDLKGLTRLELKGASLRNISHDSFLGLQELRILDLSDNRLDRIPSVGL 271

  Fly   285 SKLSNLTYLNLGGNRFSQLPAVAFLNLFHLRELHLSRLDFLQRIDSRAFVDNTHLQTLHLNNNPQ 349
            |||..|..|:||.|.|..:...||:.|..|:.|.::....|:|:.:.||.||.:|:.|:|::|..
  Fly   272 SKLVRLEQLSLGQNDFEVISEGAFMGLKQLKRLEVNGALRLKRVMTGAFSDNGNLEYLNLSSNKM 336

  Fly   350 LSDIPMRLFQGNPNILEVYMQSNSLQTLYSAQFPVDQLQKLYLGDNPLQCNCSLLWLWRLVTGNF 414
            |.::......|...:..|.:::|:|.:|....||...||.|.|.:|||.|:|.::||..|:
  Fly   337 LLEVQEGALSGLSQLKHVVLKANALTSLAEGLFPWKDLQTLDLSENPLSCDCRVMWLHNLL---- 397

  Fly   415 EGVDPGMEHAAGGAVAALAKEADDEELADEATAVASTDDGVAALAAYIAEQHIVNALHTTEPSAY 479
                             :||.|              :.|.|:.|.....|:
  Fly   398 -----------------VAKNA--------------SQDDVSELLCEFPER-------------- 417

  Fly   480 ELATSSSNRNSGILRMDRQQIGCDIWRDKVRTRRKLLTMSEGEITCPAHIVTVVCAVITCLLVAM 544
                   .|...:..::...:||    .....|::.|.         ..::....|.||.|.:
  Fly   418 -------LRGESLRHLNPAMMGC----THADPRKQALI---------GALLVGSAATITALAL-- 460

  Fly   545 IGISVLYYLRFVKRR-------------RKLLHERGPMRT--SKSIINVHDRILQGHNPGGLGLG 594
                |||..|...|.             ||   ||...:|  .:..::.|.     |:|..||:.
  Fly   461 ----VLYRCRHKIRETIKGGLWGNSALGRK---EREYQKTFCDEDYMSRHQ-----HHPCSLGIH 513

  Fly   595 MSMTLGGGNHVNGLGMTLNYPHHAQTLQAHHHYHQA-MPLQSHGG-NGNHEYQQTTLPQL----- 652
            .:..           .|...|||.   .|.|||... ||:...|. :...::||..:|..
  Fly   514 STFP-----------NTYTAPHHP---GATHHYGMCPMPVNDLGAIDPQQKFQQLVVPTATMISE 564

  Fly   653 DKLELERYLAAQ----------------TIANEYRALKPW------------------------E 677
            .||...:.|.:|                |:..:.....|.                        :
  Fly   565 KKLNNNKALVSQGAIDDSASFVLHMKSATMGRDVHQQNPQLNHYTKPQFLSATATVGDSCYSYAD 629

  Fly   678 LPVKE-----ADDEP------EHLYER-----------FDH-YEYPDTHTMSKLKQAASLNHSNS 719
            :|:..     ..::|      ||..:|           .|| |.|.:||....|:|   |..|.:
  Fly   630 VPMVHGAPLGGPNQPQLRLTQEHFKQRELYDQEMGSEILDHNYIYSNTHYSMPLEQ---LGRSKT 691

  Fly   720 SAGPSPVPPSSGKPHVVYVXRGRGTGERVSQINTDIEMVGLNHLHLHHHHHNNNNNYR 777
            .. |.|:||:....:.:....||.:.::.|               .......|||..|
  Fly   692 PT-PPPMPPALPLRNGLCATTGRRSFQQKS---------------ASQKQQQNNNTLR 733

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fili	NP_001369108.1	leucine-rich repeat	75..97	CDD:275378	6/21 (29%)
		leucine-rich repeat	98..121	CDD:275380	10/22 (45%)
		LRR_8	120..180	CDD:404697	16/59 (27%)
		leucine-rich repeat	122..145	CDD:275380	6/22 (27%)
		leucine-rich repeat	146..169	CDD:275380	6/22 (27%)
		LRR	<161..>354	CDD:227223	63/193 (33%)
		leucine-rich repeat	170..193	CDD:275380	8/22 (36%)
		leucine-rich repeat	194..217	CDD:275380	6/23 (26%)
		leucine-rich repeat	218..265	CDD:275380	13/46 (28%)
		leucine-rich repeat	266..289	CDD:275380	13/22 (59%)
		leucine-rich repeat	290..313	CDD:275380	9/22 (41%)
		leucine-rich repeat	314..338	CDD:275380	8/23 (35%)
		LRR_8	337..397	CDD:404697	17/59 (29%)
		leucine-rich repeat	339..360	CDD:275380	5/20 (25%)
trn	NP_001261796.1	leucine-rich repeat	62..80	CDD:275380	4/17 (24%)
		LRR_8	83..142	CDD:290566	19/58 (33%)
		leucine-rich repeat	84..107	CDD:275380	10/22 (45%)
		leucine-rich repeat	108..131	CDD:275380	6/22 (27%)
		LRR_RI	129..421	CDD:238064	96/347 (28%)
		LRR_8	132..190	CDD:290566	17/57 (30%)
		leucine-rich repeat	132..155	CDD:275380	6/22 (27%)
		leucine-rich repeat	156..179	CDD:275380	8/22 (36%)
		leucine-rich repeat	180..204	CDD:275380	6/23 (26%)
		LRR_8	203..263	CDD:290566	20/59 (34%)
		leucine-rich repeat	205..228	CDD:275380	6/22 (27%)
		leucine-rich repeat	229..252	CDD:275380	6/22 (27%)
		LRR_8	252..308	CDD:290566	24/55 (44%)
		leucine-rich repeat	253..276	CDD:275380	13/22 (59%)
		leucine-rich repeat	277..300	CDD:275380	9/22 (41%)
		leucine-rich repeat	301..322	CDD:275380	6/20 (30%)
		LRR_8	325..384	CDD:290566	17/58 (29%)
		leucine-rich repeat	326..350	CDD:275380	6/23 (26%)
		leucine-rich repeat	351..373	CDD:275380	6/21 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D187891at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm6470
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24373
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1280
	5	5.020