DRSC/TRiP Functional Genomics Resources

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Protein Alignment Fili and Lrrc24

DIOPT Version :9

Sequence 1:NP_001369108.1 Gene:Fili / 5740472 FlyBaseID:FBgn0085397 Length:789 Species:Drosophila melanogaster
Sequence 2:NP_932787.1 Gene:Lrrc24 / 378937 MGIID:3605040 Length:521 Species:Mus musculus


Alignment Length:275 Identity:82/275 - (29%)
Similarity:120/275 - (43%) Gaps:29/275 - (10%)


- Green bases have known domain annotations that are detailed below.


  Fly    22 PVLLLLLLTLVILP-----PETTAFCPSKCQCLGGEANSRALCVDAALEDVPIQLNPETKYINLT 81
            |.||||||.|::||     |.....||:.|:|........||    .|..||..:.|.|:.:.|.
Mouse     6 PTLLLLLLGLLLLPLLPGLPPRATGCPAACRCYSATVECGAL----RLRVVPPGIPPGTQTLFLQ 66

  Fly    82 VNRIRTLE-FSLPFYMKLEILDLSQNIIETLGSKNFEYQSELRTLNLSRNLVSSLHKHAFKGLTN 145
            .|.|..|| .||.....|..|.|..|.:..|.|..|..|..|..|.|:.|.:..|...||.||..
Mouse    67 DNSIAHLEQGSLAPLAALRHLYLHNNTLRALESGAFRAQPRLLELALTGNRLRGLRGGAFVGLVQ 131

  Fly   146 LLLLDLSFNRIETVHPTALSDLASLVELDLTNNNIVSLEDNCFKGMNTLEVLVFRNNRLLDVPAS 210
            |.:|.|:.|::..:.......|..|.||.|..|:|..|||....|:::|.:|....|:|..:...
Mouse   132 LRVLYLAGNQLAKLLDFTFLHLPRLQELHLQENSIELLEDQALAGLSSLALLDLSRNQLGTISKE 196

  Fly   211 NLWHLHALKSLDMSLN----------LVEFVRNDSFEGLKELLALSVQGNVMSELDLSAFEGLIS 265
            .|..|.:|:.|.::.|          |..:::    ||.:.||:...:....:|....|.:.|  
Mouse   197 ALQPLSSLQVLRLTENPWRCDCALHWLGSWIK----EGGRRLLSSRDKKITCAEPPRLALQSL-- 255

  Fly   266 LKHLDLSDNNLTMVP 280
               |::|..:|..:|
Mouse   256 ---LEVSGGSLICIP 267

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
FiliNP_001369108.1 leucine-rich repeat 75..97 CDD:275378 8/22 (36%)
leucine-rich repeat 98..121 CDD:275380 8/22 (36%)
LRR_8 120..180 CDD:404697 19/59 (32%)
leucine-rich repeat 122..145 CDD:275380 9/22 (41%)
leucine-rich repeat 146..169 CDD:275380 5/22 (23%)
LRR <161..>354 CDD:227223 32/130 (25%)
leucine-rich repeat 170..193 CDD:275380 10/22 (45%)
leucine-rich repeat 194..217 CDD:275380 6/22 (27%)
leucine-rich repeat 218..265 CDD:275380 11/56 (20%)
leucine-rich repeat 266..289 CDD:275380 4/15 (27%)
leucine-rich repeat 290..313 CDD:275380
leucine-rich repeat 314..338 CDD:275380
LRR_8 337..397 CDD:404697
leucine-rich repeat 339..360 CDD:275380
Lrrc24NP_932787.1 LRR_8 48..92 CDD:290566 15/43 (35%)
LRR 1 59..80 8/20 (40%)
LRR_RI <60..>166 CDD:238064 35/105 (33%)
leucine-rich repeat 61..83 CDD:275380 7/21 (33%)
LRR 2 83..104 7/20 (35%)
LRR_8 84..142 CDD:290566 21/57 (37%)
leucine-rich repeat 84..107 CDD:275380 8/22 (36%)
LRR 3 107..128 7/20 (35%)
leucine-rich repeat 108..131 CDD:275380 9/22 (41%)
LRR_8 131..213 CDD:290566 23/81 (28%)
LRR_4 131..171 CDD:289563 12/39 (31%)
LRR 4 131..152 4/20 (20%)
leucine-rich repeat 132..155 CDD:275380 5/22 (23%)
LRR 5 155..176 9/20 (45%)
leucine-rich repeat 156..179 CDD:275380 10/22 (45%)
LRR 6 179..200 5/20 (25%)
leucine-rich repeat 180..203 CDD:275380 6/22 (27%)
LRRCT 212..265 CDD:214507 12/61 (20%)
Ig 267..361 CDD:299845 1/1 (100%)
IG_like 274..370 CDD:214653
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 306..330
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 374..395
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24373
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.100

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