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Protein Alignment Fili and 18w

DIOPT Version :9

Sequence 1:	NP_001369108.1	Gene:	Fili / 5740472	FlyBaseID:	FBgn0085397	Length:	789	Species:	Drosophila melanogaster
Sequence 2:	NP_476814.1	Gene:	18w / 37277	FlyBaseID:	FBgn0004364	Length:	1385	Species:	Drosophila melanogaster

Alignment Length:	812	Identity:	187/812 - (23%)
Similarity:	260/812 - (32%)	Gaps:	328/812 - (40%)

- Green bases have known domain annotations that are detailed below.

  Fly    73 PETKYINLTVNRIRTLEF-------------------------------------SLP------F 94
            |..:.:|||.||||:.||                                     |||      .
  Fly   169 PSLQLLNLTQNRIRSAEFLGFSEKLCAGSALSNANGAVSGGSELQTLDVSFNELRSLPDAWGASR 233

  Fly    95 YMKLEILDLSQNIIETLGSKNFEYQSELRTLNLSRNLVSSLHKHAFKG----------------- 142
            ..:|:.|.|..|.|.||........|.||.||:|.|.:.||...||.|
  Fly   234 LRRLQTLSLQHNNISTLAPNALAGLSSLRVLNISYNHLVSLPSEAFAGNKELRELHLQGNDLYEL 298

  Fly   143 -------LTNLLLLDLSFNRIETVH--PTALSDLASLVELDLTNNNIVSLEDNCFKGMNTLEVLV 198
                   |..||:||||.|::.:.|  .:..:.|..|:.|:|:||.:..:....||.:..|::|.
  Fly   299 PKGLLHRLEQLLVLDLSGNQLTSHHVDNSTFAGLIRLIVLNLSNNALTRIGSKTFKELYFLQILD 363

  Fly   199 FRNNRLLDVPASNLWHLHALKSLDMSLNLVEFVRNDSFEGLKELLALSVQGNVMSELDLSAFEGL 263
            .|||.:..:.......|:.|.:|:::.|.:..:.|..|.||..|..|::..|::|.::..||...
  Fly   364 MRNNSIGHIEEGAFLPLYNLHTLNLAENRLHTLDNRIFNGLYVLTKLTLNNNLVSIVESQAFRNC 428

  Fly   264 ISLKHLDLSDNNLTMVPTQQLSKLSNLTYLNLGGNRFSQLPAVAFLNLFHLRELH---------- 318
            ..||.||||.|.||.|| :.:..||.|..|:||.|:.|:.....|.||..|..|.
  Fly   429 SDLKELDLSSNQLTEVP-EAVQDLSMLKTLDLGENQISEFKNNTFRNLNQLTGLRLIDNRIGNIT 492

  Fly   319 ------LSRLDFL-------QRIDSRAFVDNTHLQTLHLNNN-----------------PQLSD- 352
                  |.||..|       |.|:..||..||.::.:.|:.|                 ..||:
  Fly   493 VGMFQDLPRLSVLNLAKNRIQSIERGAFDKNTEIEAIRLDKNFLTDINGIFATLASLLWLNLSEN 557

  Fly   353 ---------IPMRL----FQGN-----------------------------------PNILEVYM 369
                     ||..|    ..||                                   ||.:|:..
  Fly   558 HLVWFDYAFIPSNLKWLDIHGNYIEALGNYYKLQEEIRVTTLDASHNRITEIGAMSVPNSIELLF 622

  Fly   370 QSN------------------------------SLQTL----YSAQFPVDQLQKLYLGDNPLQCN 400
            .:|                              ||..|    .||:.||.:   .|||.||.:|:
  Fly   623 INNNIIGQIQANTFVDKTRLARVDLYANVLSKISLNALRVAPVSAEKPVPE---FYLGGNPFECD 684

  Fly   401 CSLLWLWR---LVT---------GNFEGVDPGMEHAAGGAVAALAKEADDEELADEATAVASTDD 453
            ||:.||.|   |.|         ||.|.:   |.|:....:..||.              .|..|
  Fly   685 CSMEWLQRINNLTTRQHPHVVDLGNIECL---MPHSRSAPLRPLAS--------------LSASD 732

  Fly   454 GVAALAAYIAEQHIVNALHTTEPSAYELATSSSNRNSGILRMDRQQIGCDIWRDKVRTRRKLLTM 518
            .|...     |.|.....|..|   ||                  |..|
  Fly   733 FVCKY-----ESHCPPTCHCCE---YE------------------QCEC---------------- 755

  Fly   519 SEGEITCPA-----HIVTVVCAVITCLLVAMIGISVLYYLRFVKRRRKL--LHERGPMRTSKSII 576
               |:.||.     |..|....::.|                  .|:.|  |..|.|.
  Fly   756 ---EVICPGNCSCFHDATWATNIVDC------------------GRQDLAALPNRIPQ------- 792

  Fly   577 NVHDRILQGHNPGGLGLGMSMTLGGGNHVNGLGMTLNYPHHAQTLQAHHHYHQAMPLQSHGGNGN 641
            :|.|..|.|:|...|.:|   .|.|..::..|.:..:   :..|||                ||:
  Fly   793 DVSDLYLDGNNMPELEVG---HLTGRRNLRALYLNAS---NLMTLQ----------------NGS 835

  Fly   642 HEYQQTTLPQLDKLELERYLAAQTIANEYRAL 673
                ...|..|..|.||..........|:|:|
  Fly   836 ----LAQLVNLRVLHLENNKLTALEGTEFRSL 863

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.