Protein Alignment Fili and tsku

DIOPT Version :9

• Sequence 1: NP_001369108.1
• Gene: Fili / 5740472
• FlyBaseID: FBgn0085397
• Length: 789
• Species: Drosophila melanogaster
• Sequence 2: NP_956027.2
• Gene: tsku / 325958
• ZFINID: ZDB-GENE-030131-4683
• Length: 366
• Species: Danio rerio
• Alignment Length: 348
• Identity: 99/348 - (28%)
• Similarity: 150/348 - (43%)
• Gaps: 61/348 - (17%)

  Fly    42 CPSKCQC---LGGEANSRAL----CVDAALEDVPIQLNPETKYINLTVNRIRTLE---FSLPFYM 96
            |..:|:|   ..|..:|.:|    |......:.|:.:..:|.:::|::|.|.::.   .|.|.|.
Zfish    42 CHPQCRCEVETFGLFDSFSLTKVDCSRIGPGNTPVPIPLDTSHLDLSLNSITSISDTMLSGPGYT 106

  Fly    97 KLEILDLSQNIIETLGSKNFEYQSELRTLNLSRNLVSSLHKHAFKGLTNLLLLDLSFNRIE---- 157
            .|..||||.|:|..:..|.|.....|.||:||.|.:..|....|.||. |:.||||.|:.:
Zfish   107 TLVSLDLSSNLIAQISPKAFSKLRYLETLDLSSNALEGLSDGCFTGLP-LVELDLSENQFKEFNL 170

  Fly   158 TVHPTALSDLASLVELDLTNNNIVSLEDNCFKGMNTLEVLVFRNNRLLDVPASNLWHLHALKSLD 222
            .:..|...||..:|  ||:.|.:.|               :||.     .|...|:    :|||.
Zfish   171 DLFTTRTQDLPIMV--DLSRNLLTS---------------IFRR-----TPGHPLY----IKSLM 209

  Fly   223 MSLNLVEFVRNDSFEGLKELLALSVQGNVMSELDLSAFEGLISLKHLDLSD-NNLTMVPTQQLSK 286
            ::.|.::.|  ....|: .|..|::.||::|.:|..||:.|..|.||.||. :.||::.......
Zfish   210 LAGNQLKTV--PKLNGI-PLQYLNLDGNLISSIDTGAFDSLTELVHLSLSGLSELTLIHPGAFRS 271

  Fly   287 LSNLTYLNLGGNR---------FSQLPAVAFLNLFHLRELHLSRLDFLQ--RIDSRAFVDNTHLQ 340
            |.||..|:|..|.         ||.|.::..|||.:.....|||..|:|  .|.|.....|.|..
Zfish   272 LKNLQALDLSNNSQLKTLNPDVFSGLVSLQELNLSNTAVTPLSRTVFMQMPNIKSITLGPNVHCW 336

  Fly   341 TLHLNNNPQLSDIPMRLFQGNPN 363
            ..|     :......::.|..||
Zfish   337 KTH-----KQGQFHRQIGQAKPN 354

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fili	NP_001369108.1	leucine-rich repeat	75..97	CDD:275378	7/24 (29%)
		leucine-rich repeat	98..121	CDD:275380	9/22 (41%)
		LRR_8	120..180	CDD:404697	23/63 (37%)
		leucine-rich repeat	122..145	CDD:275380	10/22 (45%)
		leucine-rich repeat	146..169	CDD:275380	9/26 (35%)
		LRR	<161..>354	CDD:227223	56/204 (27%)
		leucine-rich repeat	170..193	CDD:275380	5/22 (23%)
		leucine-rich repeat	194..217	CDD:275380	4/22 (18%)
		leucine-rich repeat	218..265	CDD:275380	15/46 (33%)
		leucine-rich repeat	266..289	CDD:275380	8/23 (35%)
		leucine-rich repeat	290..313	CDD:275380	10/31 (32%)
		leucine-rich repeat	314..338	CDD:275380	8/25 (32%)
		LRR_8	337..397	CDD:404697	5/27 (19%)
		leucine-rich repeat	339..360	CDD:275380	1/20 (5%)
tsku	NP_956027.2	leucine-rich repeat	82..107	CDD:275380	7/24 (29%)
		LRR_8	106..165	CDD:290566	25/59 (42%)
		LRR_RI	108..311	CDD:238064	71/232 (31%)
		leucine-rich repeat	108..131	CDD:275380	9/22 (41%)
		leucine-rich repeat	132..153	CDD:275380	8/20 (40%)
		leucine-rich repeat	155..176	CDD:275380	6/20 (30%)
		leucine-rich repeat	177..220	CDD:275380	16/70 (23%)
		LRR_8	206..257	CDD:290566	19/53 (36%)
		leucine-rich repeat	226..249	CDD:275380	9/22 (41%)
		LRR_8	248..308	CDD:290566	19/59 (32%)
		leucine-rich repeat	250..274	CDD:275380	8/23 (35%)
		leucine-rich repeat	275..299	CDD:275380	7/23 (30%)
		leucine-rich repeat	300..323	CDD:275380	8/22 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24373
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.100