DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Fili and Lrfn5

DIOPT Version :9

Sequence 1:NP_001369108.1 Gene:Fili / 5740472 FlyBaseID:FBgn0085397 Length:789 Species:Drosophila melanogaster
Sequence 2:NP_001101494.1 Gene:Lrfn5 / 314164 RGDID:1309357 Length:719 Species:Rattus norvegicus


Alignment Length:535 Identity:117/535 - (21%)
Similarity:172/535 - (32%) Gaps:209/535 - (39%)


- Green bases have known domain annotations that are detailed below.


  Fly    42 CPSKCQCLGGEANSRALCVDAALEDVPIQLNPETKYINLTVNRIRTLEFSLPFYMKLEILDLSQN 106
            ||.:|.|.....|...||....|..||..::.            ||:|           |.|:.|
  Rat    20 CPKRCVCQILSPNLATLCAKKGLLFVPPNIDR------------RTVE-----------LRLADN 61

  Fly   107 IIETLGSKNFEYQSELRTLNLSRNLVSSLHKHAFKGLTNLLLLDLSFNRIETVHPTALSDLASLV 171
            .:..:..|:|...:.|..|.||||.:|.:..|||..|.||..|.|:.||:..             
  Rat    62 FVTNIKRKDFANMTSLVDLTLSRNTISFITPHAFADLRNLRALHLNSNRLTK------------- 113

  Fly   172 ELDLTNNNIVSLEDNCFKGMNTLEVLVFRNNRLLDVPASNLWHLHALKSLDMSLNLVEFVRNDSF 236
                                                                       :.||.|
  Rat   114 -----------------------------------------------------------ITNDMF 119

  Fly   237 EGLKELLALSVQGNVMSELDLSAFEGLISLKHLDLSDNNLTMVPTQQLSKLSNLTYLNLGGNRFS 301
            .||..|..|.:..|.::.:..:||:.:.:|:.||||.|||..:|...:.|:.:|..|:|..|...
  Rat   120 SGLSNLHHLILNNNQLTLISSTAFDDVFALEELDLSYNNLETIPWDAVEKMVSLHTLSLDHNMID 184

  Fly   302 QLPAVAFLNLFHLRELHLSRLDFLQRIDSRAFVDNTHLQTLHLNNNPQLSDIPMRLFQGNPNILE 366
            .:|...|   .||.:  ::|||          |.:..||.|.          |..|||       
  Rat   185 NIPKGTF---SHLHK--MTRLD----------VTSNKLQKLP----------PDPLFQ------- 217

  Fly   367 VYMQSNSLQTLYSAQFPVDQLQKLYLGDNPLQCNCSLLWLWR--------------LVTGNFEGV 417
                  ..|.|.::.........|..|.|||.|||.||||.|              |:||.:...
  Rat   218 ------RAQVLATSGIISPSTFALSFGGNPLHCNCELLWLRRLSREDDLETCASPALLTGRYFWS 276

  Fly   418 DPGME---------------------------HAAGGAVAALAKEADDEELADEATAVASTDDGV 455
            .|..|                           .|.|....|:...:.:.:|...||.....|:|.
  Rat   277 IPEEEFLCEPPLITRHTHEMRVLEGQRATLRCKARGDPEPAIHWISPEGKLISNATRSLVYDNGT 341

  Fly   456 ---------------------AALAAYIAEQHIV---------NALHTTEPSAYELATSS---SN 487
                                 |..|....:.||:         |.:|..:|.:.:::||:   ||
  Rat   342 LDILITTVKDTGAFTCIASNPAGEATQTMDLHIIKLPHLLNSTNNIHEPDPGSSDISTSTKSGSN 406

  Fly   488 RNS--GILRMDRQQI 500
            .:|  |..:|.:.:|
  Rat   407 ASSSNGDTKMSQDKI 421

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
FiliNP_001369108.1 leucine-rich repeat 75..97 CDD:275378 3/21 (14%)
leucine-rich repeat 98..121 CDD:275380 5/22 (23%)
LRR_8 120..180 CDD:404697 17/59 (29%)
leucine-rich repeat 122..145 CDD:275380 11/22 (50%)
leucine-rich repeat 146..169 CDD:275380 5/22 (23%)
LRR <161..>354 CDD:227223 35/192 (18%)
leucine-rich repeat 170..193 CDD:275380 0/22 (0%)
leucine-rich repeat 194..217 CDD:275380 0/22 (0%)
leucine-rich repeat 218..265 CDD:275380 10/46 (22%)
leucine-rich repeat 266..289 CDD:275380 10/22 (45%)
leucine-rich repeat 290..313 CDD:275380 6/22 (27%)
leucine-rich repeat 314..338 CDD:275380 5/23 (22%)
LRR_8 337..397 CDD:404697 12/59 (20%)
leucine-rich repeat 339..360 CDD:275380 6/20 (30%)
Lrfn5NP_001101494.1 LRR 1 52..73 8/31 (26%)
leucine-rich repeat 53..76 CDD:275380 7/33 (21%)
PPP1R42 56..211 CDD:411060 56/241 (23%)
LRR 2 76..97 10/20 (50%)
leucine-rich repeat 77..100 CDD:275380 11/22 (50%)
LRR 3 100..121 9/92 (10%)
leucine-rich repeat 101..124 CDD:275380 10/94 (11%)
LRR 4 124..145 5/20 (25%)
leucine-rich repeat 125..148 CDD:275380 5/22 (23%)
LRR 5 148..169 9/20 (45%)
leucine-rich repeat 149..172 CDD:275380 10/22 (45%)
LRR 6 172..193 6/23 (26%)
leucine-rich repeat 173..196 CDD:275380 8/25 (32%)
LRR 7 196..217 9/42 (21%)
leucine-rich repeat 197..215 CDD:275380 8/37 (22%)
TPKR_C2 240..>272 CDD:417692 13/31 (42%)
IgI_SALM5_like 287..374 CDD:409421 10/86 (12%)
Ig strand B 304..308 CDD:409421 0/3 (0%)
Ig strand C 317..321 CDD:409421 1/3 (33%)
Ig strand E 340..344 CDD:409421 1/3 (33%)
Ig strand F 354..359 CDD:409421 0/4 (0%)
Ig strand G 367..370 CDD:409421 0/2 (0%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 383..416 9/32 (28%)
FN3 421..494 CDD:419708 1/1 (100%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 614..719
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
11.000

Return to query results.
Submit another query.