DRSC/TRiP Functional Genomics Resources

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Protein Alignment Fili and Chad

DIOPT Version :9

Sequence 1:NP_001369108.1 Gene:Fili / 5740472 FlyBaseID:FBgn0085397 Length:789 Species:Drosophila melanogaster
Sequence 2:NP_062037.1 Gene:Chad / 29195 RGDID:2336 Length:358 Species:Rattus norvegicus


Alignment Length:387 Identity:105/387 - (27%)
Similarity:152/387 - (39%) Gaps:79/387 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly    23 VLLLLLLTLVILPPETTAFCPSKCQCLGGEANSRALCVDAALEDVPIQLNPETKYINLTVNRIRT 87
            ||||.|:.|.||.|...| ||..|.|.|.  ....:|....|:.:| :::..||           
  Rat     4 VLLLSLVFLAILLPALAA-CPQNCHCHGD--LQHVICDKVGLQKIP-KVSETTK----------- 53

  Fly    88 LEFSLPFYMKLEILDLSQNIIETLGSKNFEYQSELRTLNLSRNLVSSLHKHAFKGLTNLLLLDLS 152
                        :|:|.:|....|.:.:|.....|.:|:|....:..:...||:||..|:.|.||
  Rat    54 ------------LLNLQRNNFPVLAANSFRTVPNLVSLHLQHCNIREVAAGAFRGLKQLIYLYLS 106

  Fly   153 FNRIETVHPTALSDLASLVELDLTNNNIVSLEDNCFKGMNTLEVLVFRNNRLLDVPASNLWHLHA 217
            .|.|..:...|..||..|..|.|.:|.:..|.......:..|.:|...||::             
  Rat   107 HNDIRVLRAGAFDDLTELTYLYLDHNKVSELPRGLLSPLVNLFILQLNNNKI------------- 158

  Fly   218 LKSLDMSLNLVEFVRNDSFEGLKELLALSVQGNVMSELDLSAFEGLISLKHLDLSDNNLTMVPTQ 282
                                               .||...||:|...|:.|.||:|.||.:...
  Rat   159 -----------------------------------RELRAGAFQGAKDLRWLYLSENALTSLHPG 188

  Fly   283 QLSKLSNLTYLNLGGNRFSQLPAVAFLNLFHLRELHLSRLDFLQRIDSRAFVD-NTHLQTLHLNN 346
            .|..:.||...:|..|:.|..|:.|...|..:.||.||. :.|:.|...||.. ..:|:||.|:|
  Rat   189 SLDDVENLAKFHLDRNQLSSYPSAALSKLRVVEELKLSH-NPLKSIPDNAFQSFGRYLETLWLDN 252

  Fly   347 NPQLSDIPMRLFQGNPNILEVYMQSNSLQTLYSAQFPVDQLQKLYLGDNPLQCNCSLLWLWR 408
            . .|.......|.|...:..|::::|.|..|.|. ||.|.|:.|.|.:||.:|.|.|..|.|
  Rat   253 T-NLEKFSDAAFAGVTTLKHVHLENNRLNQLPST-FPFDNLETLTLTNNPWKCTCQLRGLRR 312

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
FiliNP_001369108.1 leucine-rich repeat 75..97 CDD:275378 2/21 (10%)
leucine-rich repeat 98..121 CDD:275380 5/22 (23%)
LRR_8 120..180 CDD:404697 20/59 (34%)
leucine-rich repeat 122..145 CDD:275380 7/22 (32%)
leucine-rich repeat 146..169 CDD:275380 9/22 (41%)
LRR <161..>354 CDD:227223 47/193 (24%)
leucine-rich repeat 170..193 CDD:275380 5/22 (23%)
leucine-rich repeat 194..217 CDD:275380 4/22 (18%)
leucine-rich repeat 218..265 CDD:275380 5/46 (11%)
leucine-rich repeat 266..289 CDD:275380 8/22 (36%)
leucine-rich repeat 290..313 CDD:275380 7/22 (32%)
leucine-rich repeat 314..338 CDD:275380 8/24 (33%)
LRR_8 337..397 CDD:404697 20/59 (34%)
leucine-rich repeat 339..360 CDD:275380 7/20 (35%)
ChadNP_062037.1 LRRNT 22..48 CDD:279764 8/28 (29%)
LRR 1 51..72 7/43 (16%)
leucine-rich repeat 52..75 CDD:275380 7/45 (16%)
LRR_8 74..134 CDD:290566 20/59 (34%)
LRR 2 75..96 5/20 (25%)
leucine-rich repeat 76..99 CDD:275380 7/22 (32%)
LRR_RI <89..281 CDD:238064 62/241 (26%)
LRR 3 99..120 7/20 (35%)
leucine-rich repeat 100..123 CDD:275380 9/22 (41%)
LRR 4 123..144 5/20 (25%)
leucine-rich repeat 124..147 CDD:275380 5/22 (23%)
LRR_8 147..206 CDD:290566 21/106 (20%)
LRR 5 147..168 8/68 (12%)
leucine-rich repeat 148..171 CDD:275380 9/70 (13%)
LRR 6 171..192 8/20 (40%)
leucine-rich repeat 172..195 CDD:275380 8/22 (36%)
LRR_8 195..255 CDD:290566 21/61 (34%)
LRR 7 195..216 7/20 (35%)
leucine-rich repeat 196..219 CDD:275380 7/22 (32%)
LRR 8 219..240 8/21 (38%)
leucine-rich repeat 220..243 CDD:275380 8/23 (35%)
LRR_8 243..300 CDD:290566 19/58 (33%)
LRR 9 244..265 7/21 (33%)
leucine-rich repeat 245..268 CDD:275380 8/23 (35%)
LRR 10 268..289 7/21 (33%)
LRRCT 299..346 CDD:214507 7/14 (50%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 321..358
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24373
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.100

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