DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fili and Elfn1

DIOPT Version :9

Sequence 1:	NP_001369108.1	Gene:	Fili / 5740472	FlyBaseID:	FBgn0085397	Length:	789	Species:	Drosophila melanogaster
Sequence 2:	NP_001099383.1	Gene:	Elfn1 / 288512	RGDID:	1308787	Length:	829	Species:	Rattus norvegicus

Alignment Length:	193	Identity:	53/193 - (27%)
Similarity:	83/193 - (43%)	Gaps:	16/193 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 PWLCGAIPVLLLLLLTLVILPPETTAFCPSKCQCLGGEANS--RALCV--DAALEDVPIQLNPET 75
            ||:..|...||           .........|..:.|:...  .|:|.  ....|.:|.|:|...
  Rat     9 PWVLVAAATLL-----------HACGLAQGDCWLIEGDKGFVWLAICSQNQPPYEAIPQQINNTI 62

  Fly    76 KYINLTVNRIRTLEF-SLPFYMKLEILDLSQNIIETLGSKNFEYQSELRTLNLSRNLVSSLHKHA 139
            ..:.|..||||:::: ||..:..|..|:|::|.|..:....|..|..|:.|.|..|.:.:|.:..
  Rat    63 VDLRLNENRIRSVQYASLSRFGNLTYLNLTKNEIGYIEDGAFSGQFNLQVLQLGYNRLRNLTEGM 127

  Fly   140 FKGLTNLLLLDLSFNRIETVHPTALSDLASLVELDLTNNNIVSLEDNCFKGMNTLEVLVFRNN 202
            .:||:.|..|.|..|.||.|..:|..:..::|.:||:.|.|..|....|.|:..|.|....:|
  Rat   128 LRGLSKLEYLYLQANLIEVVMASAFWECPNIVNIDLSMNRIQQLGSGTFAGLTKLSVCEIYSN 190

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fili	NP_001369108.1	leucine-rich repeat	75..97	CDD:275378	7/22 (32%)
		leucine-rich repeat	98..121	CDD:275380	7/22 (32%)
		LRR_8	120..180	CDD:404697	19/59 (32%)
		leucine-rich repeat	122..145	CDD:275380	7/22 (32%)
		leucine-rich repeat	146..169	CDD:275380	8/22 (36%)
		LRR	<161..>354	CDD:227223	12/42 (29%)
		leucine-rich repeat	170..193	CDD:275380	8/22 (36%)
		leucine-rich repeat	194..217	CDD:275380	3/9 (33%)
		leucine-rich repeat	218..265	CDD:275380
		leucine-rich repeat	266..289	CDD:275380
		leucine-rich repeat	290..313	CDD:275380
		leucine-rich repeat	314..338	CDD:275380
		LRR_8	337..397	CDD:404697
		leucine-rich repeat	339..360	CDD:275380
Elfn1	NP_001099383.1	LRR	<44..>186	CDD:227223	44/141 (31%)
		leucine-rich repeat	65..85	CDD:275378	7/19 (37%)
		LRR_8	85..144	CDD:404697	18/58 (31%)
		leucine-rich repeat	86..109	CDD:275378	7/22 (32%)
		leucine-rich repeat	110..133	CDD:275378	7/22 (32%)
		leucine-rich repeat	134..157	CDD:275378	8/22 (36%)
		leucine-rich repeat	158..171	CDD:275378	5/12 (42%)
		LRRCT	190..>228	CDD:214507	1/1 (100%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24373
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.100