DRSC/TRiP Functional Genomics Resources

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Protein Alignment Fili and Gp1ba

DIOPT Version :9

Sequence 1:NP_001369108.1 Gene:Fili / 5740472 FlyBaseID:FBgn0085397 Length:789 Species:Drosophila melanogaster
Sequence 2:NP_034456.2 Gene:Gp1ba / 14723 MGIID:1333744 Length:734 Species:Mus musculus


Alignment Length:410 Identity:98/410 - (23%)
Similarity:164/410 - (40%) Gaps:81/410 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly   146 LLLLDLSFNRIETVHPTALSDLASLVELDLTNNNIVSLEDNCFKGMNTLEVLVFRNNRLLDVPA- 209
            |:||.|..:.:.:.|..::|.:.||:|::..|..:.:|.                    .|:|| 
Mouse     4 LILLFLLPSPLHSQHTCSISKVTSLLEVNCENKKLTALP--------------------ADLPAD 48

  Fly   210 SNLWHL--HALKSLDMSLNLVEFVR-NDSFEGLKELLALSVQGNVMSELDLSAFEGLISLKHLDL 271
            :.:.||  :.|.:.. :.:||.|.. ...:....||.:|...|.            ||.|::|||
Mouse    49 TGILHLGENQLGTFS-TASLVHFTHLTYLYLDRCELTSLQTNGK------------LIKLENLDL 100

  Fly   272 SDNNLTMVPTQQLSKLSNLTYLNLGGNRFSQLPAVAFLNLFHLRELHLSRLDFLQRIDSRAFVDN 336
            |.|||..:|:...: |..||.|::..|:...|.......|..|:||:|...| |:.:.....:..
Mouse   101 SHNNLKSLPSLGWA-LPALTTLDVSFNKLGSLSPGVLDGLSQLQELYLQNND-LKSLPPGLLLPT 163

  Fly   337 THLQTLHLNNNPQLSDIPMRLFQGNPNILEVYMQSNSLQTLYSAQFPVDQLQKLYLGDNPLQCNC 401
            |.|:.|:|.|| :|.::|..|..|..::..:|:|.|.|:|:....|....|..::|..|...|:|
Mouse   164 TKLKKLNLANN-KLRELPSGLLDGLEDLDTLYLQRNWLRTIPKGFFGTLLLPFVFLHANSWYCDC 227

  Fly   402 SLL-------------WLWRLVTGNFEGVDPGMEHAAGGAVAALAKEADDEELADE-----ATAV 448
            .:|             :||:      :|||  ::.......:......|:..:...     .|:.
Mouse   228 EILYFRHWLQENANNVYLWK------QGVD--VKDTTPNVASVRCANLDNAPVYSYPGKGCPTSS 284

  Fly   449 ASTD----DGVAALAAYIAE-QHIVNA-LHTTEPSAYELATSSSNRNSGILRMDRQQIGCDIWRD 507
            ..||    |.:..:.|...| :...|. :|||..|....|.|:|        .|.|.|.......
Mouse   285 GDTDYDDYDDIPDVPATRTEVKFSTNTKVHTTHWSLLAAAPSTS--------QDSQMISLPPTHK 341

  Fly   508 KVRTRRKLL-TMSEGEITCP 526
            ..:.:...: |.|.|..|.|
Mouse   342 PTKKQSTFIHTQSPGFTTLP 361

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
FiliNP_001369108.1 leucine-rich repeat 75..97 CDD:275378
leucine-rich repeat 98..121 CDD:275380
LRR_8 120..180 CDD:404697 10/33 (30%)
leucine-rich repeat 122..145 CDD:275380
leucine-rich repeat 146..169 CDD:275380 6/22 (27%)
LRR <161..>354 CDD:227223 50/196 (26%)
leucine-rich repeat 170..193 CDD:275380 4/22 (18%)
leucine-rich repeat 194..217 CDD:275380 5/25 (20%)
leucine-rich repeat 218..265 CDD:275380 9/47 (19%)
leucine-rich repeat 266..289 CDD:275380 10/22 (45%)
leucine-rich repeat 290..313 CDD:275380 6/22 (27%)
leucine-rich repeat 314..338 CDD:275380 6/23 (26%)
LRR_8 337..397 CDD:404697 19/59 (32%)
leucine-rich repeat 339..360 CDD:275380 8/20 (40%)
Gp1baNP_034456.2 LRR 28..>204 CDD:227223 56/211 (27%)
leucine-rich repeat 28..47 CDD:275380 5/38 (13%)
LRR 1 48..69 4/21 (19%)
leucine-rich repeat 51..72 CDD:275380 6/21 (29%)
LRR 2 72..93 4/32 (13%)
leucine-rich repeat 73..94 CDD:275380 5/32 (16%)
LRR 3 94..115 9/21 (43%)
leucine-rich repeat 95..117 CDD:275380 10/22 (45%)
LRR 4 117..140 5/22 (23%)
leucine-rich repeat 118..141 CDD:275380 6/22 (27%)
LRR 5 141..162 6/21 (29%)
leucine-rich repeat 142..165 CDD:275380 6/23 (26%)
LRR 6 165..188 9/23 (39%)
leucine-rich repeat 166..189 CDD:275380 9/23 (39%)
LRR 7 189..210 6/20 (30%)
leucine-rich repeat 190..211 CDD:275380 6/20 (30%)
LRRCT 221..281 CDD:214507 10/67 (15%)
DUF5585 <257..539 CDD:375359 23/113 (20%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 406..429
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 460..526
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24373
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.100

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