DRSC/TRiP Functional Genomics Resources

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Protein Alignment Fili and Chad

DIOPT Version :9

Sequence 1:NP_001369108.1 Gene:Fili / 5740472 FlyBaseID:FBgn0085397 Length:789 Species:Drosophila melanogaster
Sequence 2:NP_031715.1 Gene:Chad / 12643 MGIID:1096866 Length:358 Species:Mus musculus


Alignment Length:386 Identity:99/386 - (25%)
Similarity:154/386 - (39%) Gaps:79/386 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly    24 LLLLLLTLVILPPETTAFCPSKCQCLGGEANSRALCVDAALEDVPIQLNPETKYINLTVNRIRTL 88
            ||..|:.|.||.|...| ||..|.|.|.  ....:|....|:.:| :::..||            
Mouse     5 LLFSLVFLAILLPALAA-CPQNCHCHGD--LQHVICDKVGLQKIP-KVSETTK------------ 53

  Fly    89 EFSLPFYMKLEILDLSQNIIETLGSKNFEYQSELRTLNLSRNLVSSLHKHAFKGLTNLLLLDLSF 153
                       :|:|.:|....|.:.:|.....|.:|:|....:..:...||:||..|:.|.||.
Mouse    54 -----------LLNLQRNNFPVLAANSFRTMPNLVSLHLQHCNIREVAAGAFRGLKQLIYLYLSH 107

  Fly   154 NRIETVHPTALSDLASLVELDLTNNNIVSLEDNCFKGMNTLEVLVFRNNRLLDVPASNLWHLHAL 218
            |.|..:...|..||..|..|.|.:|.:..|.......:..|.:|...||::.:            
Mouse   108 NDIRVLRAGAFDDLTELTYLYLDHNKVSELPRGLLSPLVNLFILQLNNNKIRE------------ 160

  Fly   219 KSLDMSLNLVEFVRNDSFEGLKELLALSVQGNVMSELDLSAFEGLISLKHLDLSDNNLTMVPTQQ 283
                        :|..:|:|.|:|..|.:..|.:|.|...:.:.:.:|....|..|.|:..|:..
Mouse   161 ------------LRAGAFQGAKDLRWLYLSENALSSLQPGSLDDVENLAKFHLDKNQLSSYPSAA 213

  Fly   284 LSKLSNLTYLNLGGNRFSQLPAVAFLNL-FHLRELHLSRLDFLQRIDSRAFVDNTHLQTLHLNNN 347
            ||||..:..|.|..|....:|..||.:. .:|..|.|...: |::....||...|.|:.:||:||
Mouse   214 LSKLRVVEELKLSHNPLKSIPDNAFQSFGRYLETLWLDNTN-LEKFSDAAFSGVTTLKHVHLDNN 277

  Fly   348 PQLSDIPMRLFQGNPNILEVYMQSNSLQTLYSAQFPVDQLQKLYLGDNPLQCNCSLLWLWR 408
             :|:.:|                         :.||.|.|:.|.|.:||.:|.|.|..|.|
Mouse   278 -RLNQLP-------------------------SSFPFDNLETLTLTNNPWKCTCQLRGLRR 312

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
FiliNP_001369108.1 leucine-rich repeat 75..97 CDD:275378 2/21 (10%)
leucine-rich repeat 98..121 CDD:275380 5/22 (23%)
LRR_8 120..180 CDD:404697 20/59 (34%)
leucine-rich repeat 122..145 CDD:275380 7/22 (32%)
leucine-rich repeat 146..169 CDD:275380 9/22 (41%)
LRR <161..>354 CDD:227223 49/193 (25%)
leucine-rich repeat 170..193 CDD:275380 5/22 (23%)
leucine-rich repeat 194..217 CDD:275380 4/22 (18%)
leucine-rich repeat 218..265 CDD:275380 9/46 (20%)
leucine-rich repeat 266..289 CDD:275380 9/22 (41%)
leucine-rich repeat 290..313 CDD:275380 6/23 (26%)
leucine-rich repeat 314..338 CDD:275380 6/23 (26%)
LRR_8 337..397 CDD:404697 15/59 (25%)
leucine-rich repeat 339..360 CDD:275380 7/20 (35%)
ChadNP_031715.1 LRRNT 22..48 CDD:279764 8/28 (29%)
LRR 1 51..72 7/43 (16%)
leucine-rich repeat 52..75 CDD:275380 7/45 (16%)
LRR_8 74..134 CDD:290566 20/59 (34%)
LRR 2 75..96 5/20 (25%)
leucine-rich repeat 76..99 CDD:275380 7/22 (32%)
LRR_RI <89..281 CDD:238064 59/217 (27%)
LRR 3 99..120 7/20 (35%)
leucine-rich repeat 100..123 CDD:275380 9/22 (41%)
LRR 4 123..144 5/20 (25%)
leucine-rich repeat 124..147 CDD:275380 5/22 (23%)
LRR_8 147..206 CDD:290566 16/82 (20%)
LRR 5 147..168 6/44 (14%)
leucine-rich repeat 148..171 CDD:275380 7/46 (15%)
LRR 6 171..192 5/20 (25%)
leucine-rich repeat 172..195 CDD:275380 5/22 (23%)
LRR 7 195..216 6/20 (30%)
leucine-rich repeat 196..219 CDD:275380 9/22 (41%)
LRR 8 219..240 6/20 (30%)
LRR_8 220..279 CDD:290566 18/60 (30%)
leucine-rich repeat 220..243 CDD:275380 6/22 (27%)
LRR 9 244..265 6/21 (29%)
leucine-rich repeat 245..268 CDD:275380 6/23 (26%)
LRR 10 268..289 9/46 (20%)
leucine-rich repeat 269..291 CDD:275380 10/47 (21%)
LRRCT 299..346 CDD:214507 7/14 (50%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 322..358
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24373
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.100

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