Protein Alignment Fili and Chad

DIOPT Version :10

• Sequence 1: NP_001369108.1
• Gene: Fili / 5740472
• FlyBaseID: FBgn0085397
• Length: 789
• Species: Drosophila melanogaster
• Sequence 2: NP_031715.1
• Gene: Chad / 12643
• MGIID: 1096866
• Length: 358
• Species: Mus musculus
• Alignment Length: 386
• Identity: 99/386 - (25%)
• Similarity: 154/386 - (39%)
• Gaps: 79/386 - (20%)

  Fly    24 LLLLLLTLVILPPETTAFCPSKCQCLGGEANSRALCVDAALEDVPIQLNPETKYINLTVNRIRTL 88
            ||..|:.|.||.|...| ||..|.|.|.  ....:|....|:.:| :::..||
Mouse     5 LLFSLVFLAILLPALAA-CPQNCHCHGD--LQHVICDKVGLQKIP-KVSETTK------------ 53

  Fly    89 EFSLPFYMKLEILDLSQNIIETLGSKNFEYQSELRTLNLSRNLVSSLHKHAFKGLTNLLLLDLSF 153
                       :|:|.:|....|.:.:|.....|.:|:|....:..:...||:||..|:.|.||.
Mouse    54 -----------LLNLQRNNFPVLAANSFRTMPNLVSLHLQHCNIREVAAGAFRGLKQLIYLYLSH 107

  Fly   154 NRIETVHPTALSDLASLVELDLTNNNIVSLEDNCFKGMNTLEVLVFRNNRLLDVPASNLWHLHAL 218
            |.|..:...|..||..|..|.|.:|.:..|.......:..|.:|...||::.:
Mouse   108 NDIRVLRAGAFDDLTELTYLYLDHNKVSELPRGLLSPLVNLFILQLNNNKIRE------------ 160

  Fly   219 KSLDMSLNLVEFVRNDSFEGLKELLALSVQGNVMSELDLSAFEGLISLKHLDLSDNNLTMVPTQQ 283
                        :|..:|:|.|:|..|.:..|.:|.|...:.:.:.:|....|..|.|:..|:..
Mouse   161 ------------LRAGAFQGAKDLRWLYLSENALSSLQPGSLDDVENLAKFHLDKNQLSSYPSAA 213

  Fly   284 LSKLSNLTYLNLGGNRFSQLPAVAFLNL-FHLRELHLSRLDFLQRIDSRAFVDNTHLQTLHLNNN 347
            ||||..:..|.|..|....:|..||.:. .:|..|.|...: |::....||...|.|:.:||:||
Mouse   214 LSKLRVVEELKLSHNPLKSIPDNAFQSFGRYLETLWLDNTN-LEKFSDAAFSGVTTLKHVHLDNN 277

  Fly   348 PQLSDIPMRLFQGNPNILEVYMQSNSLQTLYSAQFPVDQLQKLYLGDNPLQCNCSLLWLWR 408
             :|:.:|                         :.||.|.|:.|.|.:||.:|.|.|..|.|
Mouse   278 -RLNQLP-------------------------SSFPFDNLETLTLTNNPWKCTCQLRGLRR 312

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fili	NP_001369108.1	LRR	71..>348	CDD:443914	67/277 (24%)
		leucine-rich repeat	75..97	CDD:275378	2/21 (10%)
		leucine-rich repeat	98..121	CDD:275380	5/22 (23%)
		leucine-rich repeat	122..145	CDD:275380	7/22 (32%)
		leucine-rich repeat	146..169	CDD:275380	9/22 (41%)
		leucine-rich repeat	170..193	CDD:275380	5/22 (23%)
		leucine-rich repeat	194..217	CDD:275380	4/22 (18%)
		leucine-rich repeat	218..265	CDD:275380	9/46 (20%)
		leucine-rich repeat	266..289	CDD:275380	9/22 (41%)
		leucine-rich repeat	290..313	CDD:275380	6/23 (26%)
		leucine-rich repeat	314..338	CDD:275380	6/23 (26%)
		LRR_8	337..397	CDD:404697	15/59 (25%)
		leucine-rich repeat	339..360	CDD:275380	7/20 (35%)
Chad	NP_031715.1	LRRNT	22..48	CDD:396168	8/28 (29%)
		LRR	49..>300	CDD:443914	76/324 (23%)
		LRR 1	51..72		7/43 (16%)
		leucine-rich repeat	52..75	CDD:275380	7/45 (16%)
		LRR 2	75..96		5/20 (25%)
		leucine-rich repeat	76..99	CDD:275380	7/22 (32%)
		LRR 3	99..120		7/20 (35%)
		leucine-rich repeat	100..123	CDD:275380	9/22 (41%)
		LRR 4	123..144		5/20 (25%)
		leucine-rich repeat	124..147	CDD:275380	5/22 (23%)
		LRR 5	147..168		6/44 (14%)
		leucine-rich repeat	148..171	CDD:275380	7/46 (15%)
		LRR 6	171..192		5/20 (25%)
		leucine-rich repeat	172..195	CDD:275380	5/22 (23%)
		LRR 7	195..216		6/20 (30%)
		leucine-rich repeat	196..219	CDD:275380	9/22 (41%)
		LRR 8	219..240		6/20 (30%)
		leucine-rich repeat	220..243	CDD:275380	6/22 (27%)
		LRR 9	244..265		6/21 (29%)
		leucine-rich repeat	245..268	CDD:275380	6/23 (26%)
		LRR 10	268..289		9/46 (20%)
		leucine-rich repeat	269..291	CDD:275380	10/47 (21%)
		LRRCT	299..346	CDD:214507	7/14 (50%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	322..358