Protein Alignment Fili and si:ch211-170a17.1

DIOPT Version :10

• Sequence 1: NP_001369108.1
• Gene: Fili / 5740472
• FlyBaseID: FBgn0085397
• Length: 789
• Species: Drosophila melanogaster
• Sequence 2: XP_021336930.1
• Gene: si:ch211-170a17.1 / 101884914
• ZFINID: ZDB-LINCRNAG-131127-306
• Length: 628
• Species: Danio rerio
• Alignment Length: 486
• Identity: 141/486 - (29%)
• Similarity: 215/486 - (44%)
• Gaps: 59/486 - (12%)

  Fly    26 LLLLTLVILPPETTAFCPSKCQCLGGEANSRA-LCVDAALEDVPIQLNPETKYINLTVNRIRTL- 88
            ||.|.||.:...:|..|||:|:|   .|.||: :|.......:|..:..||:.::|:.|||:.:
Zfish    33 LLGLALVAVFVGSTLACPSRCEC---SAQSRSVICHRKRYTAIPDGVPLETRILDLSKNRIQAVN 94

  Fly    89 --EFSLPFYMKLEILDLSQNIIETLGSKNFEYQSELRTLNLSRNLVSSLHKHAFKGLTNLLLLDL 151
              :|:.  |..:|.||||.|||..:....|.....|.:|:|..|.:..|....|.||:||..||:
Zfish    95 PDDFAA--YPHIEELDLSGNIIAYVEPGAFNSLYSLHSLSLKSNRIKLLSLGVFTGLSNLTNLDI 157

  Fly   152 SFNRIETVHPTALSDLASLVELDLTNNNIVSLEDNCFKGMNTLEVLVFRNNRLLDVPASNLWHLH 216
            |.|::..:......||.:|..||:.:|.:|.:....|.|:.:||.|......|..||...|.|||
Zfish   158 SDNKVVILVDYMFQDLRNLRSLDVGDNELVYISHRAFSGLLSLESLTLERCNLTVVPTDALSHLH 222

  Fly   217 ALKSLDMSLNLVEFVRNDSFEGLKELLALSVQGNVMSELDL---SAFEGLISLKHLDLSDNNLTM 278
            .|.||.|....:..:...||:.|..|..|.:..  ...||:   ::..|| :|..|.:::.||:.
Zfish   223 NLVSLHMRYLTISTLHPYSFKKLFHLRHLEIDN--WPSLDVFPANSLHGL-NLTTLSVTNTNLST 284

  Fly   279 VPTQQLSKLSNLTYLNLGGNRFSQLPAVAFLNLFHLRELHLSRLDFLQRIDSRAFVDNTHLQTLH 343
            .|.|.|..|..||:|||..:|...:......||..||||.|:. ..|..|:..||.....|:.|:
Zfish   285 FPYQALHHLPYLTHLNLSYSRIRTVEGGLLQNLVRLRELRLAG-SHLVSIEPYAFQGIRWLRLLN 348

  Fly   344 LNNNPQLSDIPMRLFQGNPNILEVYMQSNSLQTLYSAQFPV-DQLQKLYLGDNPLQCNCSLLW-L 406
            :::                         |.|.||....|.. :.||.|.:.:|||.|:|.|:| |
Zfish   349 ISH-------------------------NRLDTLEKGAFHAPEALQVLLINNNPLVCDCRLMWLL 388

  Fly   407 WRLVTGNFEGVDPGMEHAAGGAVAALAKEADDEELADEATAV-----------ASTDDGVAALAA 460
            .|..:.:|....|... :..|:....:||..:..|::..|..           .|.::|.:|...
Zfish   389 QRHHSISFGDTQPECS-SPEGSQRRQSKEFKEALLSNYVTCTKPKIRRNRTQSVSVEEGQSAHLN 452

  Fly   461 YIAEQHIVNALHTTEPSAYELATSSSNRNSG 491
            ..||......:....|...:|    :|||.|
Zfish   453 CTAEGTPRPTISWVSPRKVQL----NNRNHG 479

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fili	NP_001369108.1	LRR	71..>348	CDD:443914	90/282 (32%)
		leucine-rich repeat	75..97	CDD:275378	7/24 (29%)
		leucine-rich repeat	98..121	CDD:275380	9/22 (41%)
		leucine-rich repeat	122..145	CDD:275380	8/22 (36%)
		leucine-rich repeat	146..169	CDD:275380	7/22 (32%)
		leucine-rich repeat	170..193	CDD:275380	7/22 (32%)
		leucine-rich repeat	194..217	CDD:275380	9/22 (41%)
		leucine-rich repeat	218..265	CDD:275380	13/49 (27%)
		leucine-rich repeat	266..289	CDD:275380	8/22 (36%)
		leucine-rich repeat	290..313	CDD:275380	8/22 (36%)
		leucine-rich repeat	314..338	CDD:275380	9/23 (39%)
		LRR_8	337..397	CDD:404697	11/60 (18%)
		leucine-rich repeat	339..360	CDD:275380	2/20 (10%)
si:ch211-170a17.1	XP_021336930.1	LRR	69..>378	CDD:443914	100/339 (29%)
		leucine-rich repeat	80..103	CDD:275380	7/24 (29%)
		leucine-rich repeat	104..127	CDD:275380	9/22 (41%)
		leucine-rich repeat	128..151	CDD:275380	8/22 (36%)
		leucine-rich repeat	152..175	CDD:275380	7/22 (32%)
		leucine-rich repeat	176..223	CDD:275380	16/46 (35%)
		leucine-rich repeat	224..247	CDD:275380	7/22 (32%)
		leucine-rich repeat	248..295	CDD:275380	14/49 (29%)
		leucine-rich repeat	296..319	CDD:275380	8/22 (36%)
		leucine-rich repeat	320..343	CDD:275380	9/23 (39%)
		leucine-rich repeat	344..363	CDD:275380	6/43 (14%)
		PCC	348..>430	CDD:188093	24/107 (22%)
		Ig_3	430..508	CDD:464046	11/54 (20%)