DRSC/TRiP Functional Genomics Resources

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Protein Alignment Fili and LOC100535105

DIOPT Version :9

Sequence 1:NP_001369108.1 Gene:Fili / 5740472 FlyBaseID:FBgn0085397 Length:789 Species:Drosophila melanogaster
Sequence 2:XP_009298331.1 Gene:LOC100535105 / 100535105 -ID:- Length:706 Species:Danio rerio


Alignment Length:396 Identity:105/396 - (26%)
Similarity:182/396 - (45%) Gaps:38/396 - (9%)


- Green bases have known domain annotations that are detailed below.


  Fly    23 VLLLLLLTLVILPPETTAFCPSKCQC----------LGGEANSRALCVDAALEDVPIQLNPETKY 77
            :|:.|.:...::..|....||..|.|          :..||.: ..|.|..|..:|.:|..:|:.
Zfish    10 LLVGLAMATFVIAAEEKISCPKLCVCEIRPWFSPSSVYMEAPT-IDCNDLGLFKLPTRLPLDTQV 73

  Fly    78 INLTVNRIRTLEFSLPFYMKLEILDLSQNIIETLGSKNFEYQSELRTLNLSRNLVSSLHKHAFKG 142
            :.|..|.|...|..|.:...:..:|||||.:.::...|.....:|.:|::..|.:.||..::...
Zfish    74 LLLQTNNIAKNEHPLDYLTNITEIDLSQNNLSSINDINIGSLPQLLSLHMEENWICSLPDNSLSQ 138

  Fly   143 LTNLLLLDLSFNRIETVHPTALSDLASLVELDLTNNNIVSLEDNCFKGMNTLEVLVFRNNRLLDV 207
            ||||..|.|:.|.|..:.|.|...|.||:.|.|.:|.:..::...|:.:..||:|:...|.:|.:
Zfish   139 LTNLQELYLNHNLISLISPEAFRGLQSLLRLHLNSNRLQIIKSEWFEPLPNLEILMIGENPVLSI 203

  Fly   208 PASNLWHLHALKSLDMS-LNLVEFVRNDSFEGLKELLALSVQGNVMSELDLSAFEGLISLKHLDL 271
            ...|...|..|:||.:: :||.: :.:|||.||..|.::|                        .
Zfish   204 QDMNFKPLRNLRSLVLTRMNLSQ-IPDDSFLGLDNLESIS------------------------F 243

  Fly   272 SDNNLTMVPTQQLSKLSNLTYLNLGGNRFSQLPAVAFLNLFHLRELHLSRLDFLQRIDSRAFVDN 336
            .||....||...|..|.:|.:|:|..|...::....|:::.||:||.::.:..|..|||.|..:.
Zfish   244 YDNTFPKVPHGALRHLKSLKFLDLNKNPIGRIQRGDFVDMLHLKELGINSMPELVSIDSFALNNL 308

  Fly   337 THLQTLHLNNNPQLSDIPMRLFQGNPNILEVYMQSNSLQTLYSAQF-PVDQLQKLYLGDNPLQCN 400
            ..|..:...|||:||.|....|...|.:..:.:..|:|..|:.... .:..|:::.:..||::|:
Zfish   309 PELTKIEATNNPKLSYIHPNAFYRLPRLETLMLNGNALSALHRITVESLPNLREVSMHSNPIRCD 373

  Fly   401 CSLLWL 406
            |.:.|:
Zfish   374 CVVRWM 379

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
FiliNP_001369108.1 leucine-rich repeat 75..97 CDD:275378 6/21 (29%)
leucine-rich repeat 98..121 CDD:275380 6/22 (27%)
LRR_8 120..180 CDD:404697 21/59 (36%)
leucine-rich repeat 122..145 CDD:275380 6/22 (27%)
leucine-rich repeat 146..169 CDD:275380 8/22 (36%)
LRR <161..>354 CDD:227223 54/193 (28%)
leucine-rich repeat 170..193 CDD:275380 5/22 (23%)
leucine-rich repeat 194..217 CDD:275380 7/22 (32%)
leucine-rich repeat 218..265 CDD:275380 12/47 (26%)
leucine-rich repeat 266..289 CDD:275380 6/22 (27%)
leucine-rich repeat 290..313 CDD:275380 5/22 (23%)
leucine-rich repeat 314..338 CDD:275380 8/23 (35%)
LRR_8 337..397 CDD:404697 14/60 (23%)
leucine-rich repeat 339..360 CDD:275380 8/20 (40%)
LOC100535105XP_009298331.1 leucine-rich repeat 52..70 CDD:275380 5/18 (28%)
leucine-rich repeat 71..93 CDD:275380 6/21 (29%)
LRR_RI 88..>273 CDD:238064 58/209 (28%)
leucine-rich repeat 95..117 CDD:275380 6/21 (29%)
LRR_8 116..176 CDD:290566 21/59 (36%)
leucine-rich repeat 118..141 CDD:275380 6/22 (27%)
leucine-rich repeat 142..165 CDD:275380 8/22 (36%)
LRR_8 165..221 CDD:290566 16/55 (29%)
leucine-rich repeat 166..189 CDD:275380 5/22 (23%)
leucine-rich repeat 190..213 CDD:275380 7/22 (32%)
LRR_8 212..272 CDD:290566 22/84 (26%)
leucine-rich repeat 214..237 CDD:275380 10/23 (43%)
leucine-rich repeat 238..261 CDD:275380 8/46 (17%)
leucine-rich repeat 262..285 CDD:275380 5/22 (23%)
leucine-rich repeat 286..310 CDD:275380 8/23 (35%)
LRR_8 309..370 CDD:290566 14/60 (23%)
leucine-rich repeat 311..333 CDD:275380 8/21 (38%)
leucine-rich repeat 336..357 CDD:275380 3/20 (15%)
leucine-rich repeat 360..372 CDD:275378 3/11 (27%)
LRRCT 368..411 CDD:214507 5/12 (42%)
IG_like 429..513 CDD:214653
Ig 437..513 CDD:299845
fn3 518..593 CDD:278470
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 1 1.000 - - mtm6470
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24373
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
33.010

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