Protein Alignment Fili and tlr9

DIOPT Version :10

• Sequence 1: NP_001369108.1
• Gene: Fili / 5740472
• FlyBaseID: FBgn0085397
• Length: 789
• Species: Drosophila melanogaster
• Sequence 2: XP_017948709.2
• Gene: tlr9 / 100494387
• XenbaseID: XB-GENE-486908
• Length: 1035
• Species: Xenopus tropicalis
• Alignment Length: 352
• Identity: 95/352 - (26%)
• Similarity: 140/352 - (39%)
• Gaps: 105/352 - (29%)

  Fly   101 LDLSQNIIETLGSKNFEYQSELRTLNLSRNLVSS-LHKHAFKGLTNLLLLDLSFNRIETVHPTAL 164
            :|||.|.|.::....|....|:..||:|.|.::. |:...|..|.:|..||||.||.:..:..||
 Frog   484 VDLSFNNIGSIYPDEFLGMDEIECLNMSYNYINQRLNGTQFGHLKSLRHLDLSHNRFDMYYYKAL 548

  Fly   165 SD------------------------------LASLVELDLTNNNIVSLEDNCFKGMNTLEVLVF 199
            |:                              |.|||||:| |||.:.|........::||.|.|
 Frog   549 SELPRLKILNLAHNDYQFMMKGVNHRLDFLENLTSLVELNL-NNNFIGLRITRELKSHSLETLRF 612

  Fly   200 RNNRL-------LDVPASNLWHLHALKSLDMSLNLVEFVRNDSFEGLKELLALSVQGNVMSELDL 257
            |||.|       .|...:...:|.:||.||:|.|.:..:.|:..|.|.|
 Frog   613 RNNELGSSWQYGKDTYLNMFTNLRSLKILDISYNQLPVIPNEVLEKLPE---------------- 661

  Fly   258 SAFEGLISLKHLDLSDNNLTMVPTQQLSKLSNLTYLNLGGNRFSQLPA------VAFLNLFHLRE 316
                   ||:.|:||.|.|......:.:.|.||..|:||.|..::|.|      :|||||.:.:
 Frog   662 -------SLQKLNLSHNKLYTFNWAKTAHLGNLAILDLGFNALTKLRANLTESNIAFLNLTYNK- 718

  Fly   317 LHLSRLDFLQRIDSRAFVDNTHLQTLHLNNNPQLSDIPMRLFQGNPNILEVYMQSNSLQTLYSAQ 381
                    :..:|...|...:.|:.|.|:|                         |.::|::...
 Frog   719 --------INSLDKDFFDSFSELKQLILSN-------------------------NLIKTIHITS 750

  Fly   382 FPVDQLQ---KLYLGDNPLQCNCSLLW 405
            ||::.||   .|.:..||.||.|...|
 Frog   751 FPINFLQNLDSLDVSGNPFQCTCKAYW 777

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fili	NP_001369108.1	LRR	71..>348	CDD:443914	82/290 (28%)
		leucine-rich repeat	75..97	CDD:275378
		leucine-rich repeat	98..121	CDD:275380	6/19 (32%)
		leucine-rich repeat	122..145	CDD:275380	7/23 (30%)
		leucine-rich repeat	146..169	CDD:275380	11/52 (21%)
		leucine-rich repeat	170..193	CDD:275380	9/22 (41%)
		leucine-rich repeat	194..217	CDD:275380	10/29 (34%)
		leucine-rich repeat	218..265	CDD:275380	10/46 (22%)
		leucine-rich repeat	266..289	CDD:275380	7/22 (32%)
		leucine-rich repeat	290..313	CDD:275380	12/28 (43%)
		leucine-rich repeat	314..338	CDD:275380	2/23 (9%)
		LRR_8	337..397	CDD:404697	12/62 (19%)
		leucine-rich repeat	339..360	CDD:275380	4/20 (20%)
tlr9	XP_017948709.2	LRR_8	67..139	CDD:404697
		leucine-rich repeat	69..92	CDD:275380
		leucine-rich repeat	93..128	CDD:275380
		LRR	123..>429	CDD:443914
		leucine-rich repeat	129..148	CDD:275380
		leucine-rich repeat	149..172	CDD:275380
		leucine-rich repeat	173..203	CDD:275380
		leucine-rich repeat	204..224	CDD:275380
		leucine-rich repeat	225..248	CDD:275380
		leucine-rich repeat	249..289	CDD:275380
		leucine-rich repeat	290..311	CDD:275380
		leucine-rich repeat	314..337	CDD:275380
		leucine-rich repeat	353..394	CDD:275380
		leucine-rich repeat	395..418	CDD:275380
		leucine-rich repeat	482..504	CDD:275380	6/19 (32%)
		LRR	489..>767	CDD:443914	86/335 (26%)
		leucine-rich repeat	505..529	CDD:275380	7/23 (30%)
		leucine-rich repeat	530..553	CDD:275380	10/22 (45%)
		leucine-rich repeat	554..583	CDD:275380	1/28 (4%)
		leucine-rich repeat	584..637	CDD:275380	19/53 (36%)
		leucine-rich repeat	607..629	CDD:275380	9/21 (43%)
		leucine-rich repeat	638..662	CDD:275380	10/46 (22%)
		leucine-rich repeat	663..686	CDD:275380	7/22 (32%)
		leucine-rich repeat	687..708	CDD:275380	7/20 (35%)
		leucine-rich repeat	709..732	CDD:275380	7/31 (23%)
		leucine-rich repeat	733..751	CDD:275380	6/42 (14%)
		PCC	738..>821	CDD:188093	15/65 (23%)
		SEFIR	875..1017	CDD:474043