Protein Alignment Fili and tlrs5

DIOPT Version :9

• Sequence 1: NP_001369108.1
• Gene: Fili / 5740472
• FlyBaseID: FBgn0085397
• Length: 789
• Species: Drosophila melanogaster
• Sequence 2: XP_002937550.2
• Gene: tlrs5 / 100489423
• XenbaseID: XB-GENE-22201327
• Length: 653
• Species: Xenopus tropicalis
• Alignment Length: 618
• Identity: 132/618 - (21%)
• Similarity: 221/618 - (35%)
• Gaps: 237/618 - (38%)

  Fly    25 LLLLLTLVILPPET--TAFCP----SKCQCLGGEANSRALCVDAALEDVPIQLNPETKYINLTVN 83
            ::||..:::|.|.:  :.|.|    |.|:....:::....|:...|..:|..:.|:|:.:..:.|
 Frog     1 MMLLPFIILLFPVSLLSGFQPLSNNSNCKAFQDKSHFVFNCLANGLYSIPSHIPPQTQSLLFSFN 65

  Fly    84 RIRTL-EFSLPFYMKLEILDLSQNIIE---TLGSKNFEYQSELRTLNLSRNLVSSLHKHAFKGLT 144
            ||.:: :.|.|..:.|:.|.|...:..   ::|...|.....|.||:|..|.:.:||..||:||:
 Frog    66 RIPSISQDSFPDLLHLQTLLLGSQVTPGTFSVGKSAFRGFPNLITLDLGGNRIINLHPEAFEGLS 130

  Fly   145 NLLLLDLSFNRI-ETVHPTAL-SDLASLVELDLTNNNIVSLE-DNCFKGMNTLEVLVFRNNR--- 203
            .|.:|.|..|.: |:|..:.: .||.||.:|||:.|||..:. |..|..::::..|:.:.|:
 Frog   131 WLEVLLLDHNGLDESVLESGMFKDLTSLKKLDLSFNNIRRVRPDPTFLKLSSISFLLLKFNKVSM 195

  Fly   204 ---------------LLDV---------------PASNL-----------WH------------- 214
                           |||:               |.:|:           |:
 Frog   196 LCGEDLQNLQGRRLQLLDMSSNPLQLSSTPHCTNPFNNITLGTLDVSSMGWNAEMVENFVRTISG 260

  Fly   215 -------------------LHALK----------------------------------------S 220
                               .|.||                                        |
 Frog   261 TQVDYIKMRHTAGLGSGFGFHNLKDPNKDTFSGLNSSNVQILDLSNGFISHLVPQLFSAFPKLLS 325

  Fly   221 LDMSLNLVEFVRNDSFEGLKELLALSVQGNVMSELDLSAFEGL--ISLKHLDLSDNNLTMVPTQQ 283
            ||:|.|.:..:.:.:|.||.||::|::.||::.||..|:|:||  .|||.||||.|::..|....
 Frog   326 LDLSSNQINRMSSGAFSGLGELVSLNLSGNLLGELMGSSFQGLGATSLKTLDLSSNHIGAVQYGA 390

  Fly   284 LSKLSNLTYLNLGGNRFSQLPAV------------------------------------------ 306
            |...:.||.|||..|..:::|..
 Frog   391 LDSFTALTSLNLRDNALNKIPPTKLQGVTFVLLKQNRISDIYNIISFCPHATILDLSSNRLTDFR 455

  Fly   307 -----------------------------------------------------------AFLNLF 312
                                                                       .|::|.
 Frog   456 SLWQILELQSLKYLSLASNSLYRCSLPHTSNITRTSGLVYLDLSDNALGPVLKSGECGDIFMHLG 520

  Fly   313 HLRELHLSRLDFLQRIDSRAFVDNTHLQTLHLNNNPQLSDIPMRLFQGNPNILEVYMQSNSLQTL 377
            .|:.|:|:| :.|..|....|...:.||||.|:.| ...:|...||.|...:..:.:..::|.||
 Frog   521 SLKSLNLAR-NQLSNIPDTMFRSLSSLQTLDLSGN-GFKEIQSNLFTGLTALKTLNLGKSNLVTL 583

  Fly   378 YSAQF-PVDQLQKLYLGDNPLQCNCSL--LWLW 407
            .|:.. |:..|:.:.|.:..|.|:|||  .|.|
 Frog   584 SSSVLDPLGSLESIDLSEVTLVCDCSLWDFWKW 616

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fili	NP_001369108.1	leucine-rich repeat	75..97	CDD:275378	6/22 (27%)
		leucine-rich repeat	98..121	CDD:275380	5/25 (20%)
		LRR_8	120..180	CDD:404697	25/61 (41%)
		leucine-rich repeat	122..145	CDD:275380	11/22 (50%)
		leucine-rich repeat	146..169	CDD:275380	8/24 (33%)
		LRR	<161..>354	CDD:227223	74/413 (18%)
		leucine-rich repeat	170..193	CDD:275380	9/23 (39%)
		leucine-rich repeat	194..217	CDD:275380	8/98 (8%)
		leucine-rich repeat	218..265	CDD:275380	21/88 (24%)
		leucine-rich repeat	266..289	CDD:275380	9/22 (41%)
		leucine-rich repeat	290..313	CDD:275380	9/123 (7%)
		leucine-rich repeat	314..338	CDD:275380	7/23 (30%)
		LRR_8	337..397	CDD:404697	17/60 (28%)
		leucine-rich repeat	339..360	CDD:275380	9/20 (45%)
tlrs5	XP_002937550.2	PLN00113	100..>597	CDD:215061	102/498 (20%)
		leucine-rich repeat	108..131	CDD:275380	11/22 (50%)
		leucine-rich repeat	132..157	CDD:275380	8/24 (33%)
		leucine-rich repeat	158..182	CDD:275380	9/23 (39%)
		leucine-rich repeat	183..208	CDD:275380	2/24 (8%)
		leucine-rich repeat	209..232	CDD:275380	4/22 (18%)
		leucine-rich repeat	299..322	CDD:275380	0/22 (0%)
		leucine-rich repeat	323..346	CDD:275380	8/22 (36%)
		leucine-rich repeat	347..372	CDD:275380	10/24 (42%)
		leucine-rich repeat	373..396	CDD:275380	9/22 (41%)
		leucine-rich repeat	397..440	CDD:275380	7/42 (17%)
		leucine-rich repeat	418..431	CDD:275378	0/12 (0%)
		leucine-rich repeat	441..492	CDD:275380	0/50 (0%)
		leucine-rich repeat	493..521	CDD:275380	2/27 (7%)
		leucine-rich repeat	522..545	CDD:275380	7/23 (30%)
		leucine-rich repeat	546..569	CDD:275380	10/23 (43%)
		leucine-rich repeat	570..591	CDD:275380	4/20 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24373
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010