DRSC/TRiP Functional Genomics Resources

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Protein Alignment Fili and lrrc3

DIOPT Version :9

Sequence 1:NP_001369108.1 Gene:Fili / 5740472 FlyBaseID:FBgn0085397 Length:789 Species:Drosophila melanogaster
Sequence 2:NP_001107114.1 Gene:lrrc3 / 100001372 ZFINID:ZDB-GENE-080327-13 Length:266 Species:Danio rerio


Alignment Length:261 Identity:70/261 - (26%)
Similarity:113/261 - (43%) Gaps:46/261 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly    22 PVLLLLLLTLVILPPETTAFCPSKCQCLGGEANSRAL--CVDAALEDVPIQLNPETKYINLTVNR 84
            |::..|||.::.|...:.| ||..|.|  .|.||..:  |....||::|..|..:|..:.|:.|.
Zfish    20 PLIFRLLLAVICLSVPSFA-CPKSCHC--SERNSLTVVQCSSRNLEEIPPDLPHDTVSLQLSSNH 81

  Fly    85 IRTLE----FSLPFYMKLEILDLSQNIIETLGSKNFEYQSE-LRTLNLSRNLVSSLHKHAFKGLT 144
            |..:.    .:||:   |:.||||:|.|||:.:..|:..|| ||||:||.|.:..:.|.||..|.
Zfish    82 ITKIPNQAFKNLPW---LQELDLSRNAIETVDAGAFKGVSESLRTLDLSHNHMQGVPKEAFARLH 143

  Fly   145 NLLLLDLSFNRIETVHPTALSDLASLVELDLTNNNIVSL---EDNCFKGMNTLEVLVFRNNRLLD 206
            ..:.|..:....|......|.:|    .||....|.||.   :...:.|...::||         
Zfish   144 AKISLSNNPWHCECTLQEVLREL----RLDPETVNEVSCHTSDQEKYAGKPVIQVL--------- 195

  Fly   207 VPASNLWHLHALKSLDMSL-------------NLVEFVRN---DSFEGLKELLALSVQGNVMSEL 255
            ....|..:.|. |:.|:::             .::.:||:   |:...|:.|.:|.....:..:.
Zfish   196 DSGINFCNFHH-KTTDVAMFVTMFGWFTMVIAYVIYYVRHNQEDARRHLEYLKSLPSSSQISKDF 259

  Fly   256 D 256
            |
Zfish   260 D 260

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
FiliNP_001369108.1 leucine-rich repeat 75..97 CDD:275378 6/25 (24%)
leucine-rich repeat 98..121 CDD:275380 10/22 (45%)
LRR_8 120..180 CDD:404697 19/60 (32%)
leucine-rich repeat 122..145 CDD:275380 11/22 (50%)
leucine-rich repeat 146..169 CDD:275380 4/22 (18%)
LRR <161..>354 CDD:227223 21/115 (18%)
leucine-rich repeat 170..193 CDD:275380 6/25 (24%)
leucine-rich repeat 194..217 CDD:275380 3/22 (14%)
leucine-rich repeat 218..265 CDD:275380 9/55 (16%)
leucine-rich repeat 266..289 CDD:275380
leucine-rich repeat 290..313 CDD:275380
leucine-rich repeat 314..338 CDD:275380
LRR_8 337..397 CDD:404697
leucine-rich repeat 339..360 CDD:275380
lrrc3NP_001107114.1 LRR_RI <14..161 CDD:238064 49/146 (34%)
LRRNT 38..72 CDD:214470 13/36 (36%)
leucine-rich repeat 51..74 CDD:275378 6/22 (27%)
LRR 1 71..92 4/20 (20%)
LRR_8 74..131 CDD:290566 24/59 (41%)
LRR_4 74..111 CDD:289563 14/39 (36%)
leucine-rich repeat 75..95 CDD:275378 4/19 (21%)
LRR 2 95..116 10/23 (43%)
leucine-rich repeat 96..120 CDD:275378 11/23 (48%)
LRR 3 120..141 10/20 (50%)
leucine-rich repeat 121..144 CDD:275378 11/22 (50%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24373
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
11.100

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