Protein Alignment Fili and lrrtm4l1

DIOPT Version :10

• Sequence 1: NP_001369108.1
• Gene: Fili / 5740472
• FlyBaseID: FBgn0085397
• Length: 789
• Species: Drosophila melanogaster
• Sequence 2: NP_001373591.2
• Gene: lrrtm4l1 / 100000724
• ZFINID: ZDB-GENE-080327-15
• Length: 571
• Species: Danio rerio
• Alignment Length: 475
• Identity: 117/475 - (24%)
• Similarity: 183/475 - (38%)
• Gaps: 121/475 - (25%)

  Fly    24 LLLLLLTLVILPPETTAFCPSKCQCLGGEANSRALCVDAALEDVPIQLNPETKYINLTVNRIRTL 88
            ||||..:.::|.......||..|.|.|...:    |..:|.:|||..::...:.::|..|.:.|:
Zfish    13 LLLLQASSLLLFSSGERMCPYSCHCEGKIVH----CESSAFQDVPENISVSCQGLSLRYNDLHTM 73

  Fly    89 EFSLPFYM----KLEILDLSQNIIETLGSKNFEYQSELRTLNLSRNLVSSLHKHAFKGLTNLLLL 149
               ||:..    :|..|.|..|.|..:.|:.|:....|:.|.||.|.:|.||...|.|:.||..|
Zfish    74 ---LPYQFAHLNQLLWLYLDHNQIMFVDSRAFQGVRRLKELILSSNRISQLHNVTFHGVPNLRSL 135

  Fly   150 DLSFNRIETVHPTALSDLASLVELDLTNNNIVSLEDNCFKGMNTLEVLVFRNNRLLDVPASNLWH 214
            |||:|:::.:.|                        ..|.|:..|:.|..|:|.|..:|......
Zfish   136 DLSYNKLQELQP------------------------GQFYGLRKLQNLHLRSNGLTAIPVRAFLE 176

  Fly   215 LHALKSLDMSLNLVEFVRNDSFEGLKELLALSVQGNVMSELDLSAFEGLISLKHLDLSDNNLTMV 279
            ..:|:.||:..|.:..:...:|.||..|:.|.::.|..|.::...|..|.:|:.|.|..|.:..|
Zfish   177 CRSLEFLDLGYNRLRVLTRTAFLGLSRLMELHLEHNQFSRINFFLFPRLANLRALYLQWNRIRAV 241

  Fly   280 PTQQLSKLSNLTYLNLGGNRFSQLPAVAFLNLFHLRELHLSRLDFLQRIDSRAFVDNTHLQTLHL 344
                          |.|      ||...:.               |||:|    :....:|.|.
Zfish   242 --------------NQG------LPWSWYT---------------LQRLD----ISGNEIQVLD- 266

  Fly   345 NNNPQLSDIPMRLFQGNPNILEVYMQSNSL----QTLYSAQFPVDQLQKLYLGDNPLQCN---CS 402
                     |: :||..||:..:.::||.|    |.:.:|..   .|..:.|..|...|.   |.
Zfish   267 ---------PV-VFQCLPNLQVLNLESNKLANVSQEVVAAWI---SLTTISLAGNMWDCGPGICP 318

  Fly   403 L-LWLWRLVTGNFEG------VDPGMEHAAGGAVAALAK---EADDEELADEATAVASTDDGVAA 457
            | :||     .||.|      :....:|..|..|...:|   :.||.|:..::.....|.|....
Zfish   319 LVVWL-----KNFRGTKDTNIICSSPKHLQGEKVIEASKNYIDCDDYEITAQSPLYLQTFDPNYD 378

  Fly   458 LAAYIAEQHIVNALHTTEPS 477
            |           ||..|||:
Zfish   379 L-----------ALEPTEPT 387

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fili	NP_001369108.1	LRR	71..>348	CDD:443914	66/280 (24%)
		leucine-rich repeat	75..97	CDD:275378	5/25 (20%)
		leucine-rich repeat	98..121	CDD:275380	7/22 (32%)
		leucine-rich repeat	122..145	CDD:275380	10/22 (45%)
		leucine-rich repeat	146..169	CDD:275380	7/22 (32%)
		leucine-rich repeat	170..193	CDD:275380	2/22 (9%)
		leucine-rich repeat	194..217	CDD:275380	6/22 (27%)
		leucine-rich repeat	218..265	CDD:275380	13/46 (28%)
		leucine-rich repeat	266..289	CDD:275380	5/22 (23%)
		leucine-rich repeat	290..313	CDD:275380	4/22 (18%)
		leucine-rich repeat	314..338	CDD:275380	4/23 (17%)
		LRR_8	337..397	CDD:404697	15/63 (24%)
		leucine-rich repeat	339..360	CDD:275380	4/20 (20%)
lrrtm4l1	NP_001373591.2	None