DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rgk3 and CG8641

DIOPT Version :9

Sequence 1:	NP_001286670.1	Gene:	Rgk3 / 5740446	FlyBaseID:	FBgn0085426	Length:	486	Species:	Drosophila melanogaster
Sequence 2:	NP_001261494.1	Gene:	CG8641 / 38771	FlyBaseID:	FBgn0035733	Length:	434	Species:	Drosophila melanogaster

Alignment Length:	511	Identity:	96/511 - (18%)
Similarity:	155/511 - (30%)	Gaps:	203/511 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 IHGMPGASGSATPEGGTPGYRRRRPATRSQSARITSGARSVRQKTKAQQ----QQQQQQHTLQET 92
            ||  |.|:.:.||..        |..:.|.:..:.|.:....|:|.|.:    ...|..||...:
  Fly    28 IH--PSAATTTTPNS--------RNFSASNNNNVRSNSSKSNQQTAAHRGATTHPTQIPHTHHPS 82

  Fly    93 RSYCTSEPRLSETETPPQRRKLSQRRPQTHAHRKSNAFLD----------------VPTMNMHHL 141
            .::.|.|      .:|||...::              |||                |.|..:|..
  Fly    83 TTHSTDE------ASPPQAHVVT--------------FLDESTAGGSNGAVTSSRLVTTAELHQA 127

  Fly   142 RVNDDDEDVDRLRTFSASKGGIINRGDSFRRRRSRSNSLAPSSPMHTRNGVGGLGGVAGGGSSLG 206
            .:.:...::|           .|.:.|.|                           :.|.|:.|.
  Fly   128 HMLEHHSNLD-----------AIEQADDF---------------------------IYGPGAGLS 154

  Fly   207 LGCGYNGGSSSNGFGNANAQENHQPVEFYRVEMLGSAGVGKQALLSQFRTSDCINAYDGPECDDA 271
            | |..:..|:.|               .||:.||||:..||.:::::|..:....||. |..::.
  Fly   155 L-CDDSLPSAKN---------------CYRLVMLGSSRAGKSSIVARFLGNRFEEAYT-PTIEEF 202

  Fly   272 EQNVSIILN----------------GTESELKFLTGNPESKDELEQADAFLVVYSCIDKESFTRA 320
            .:.:..|.|                .....|.||||           |.|::|:|...:|||...
  Fly   203 HRKLYRIRNEVFQLDILDTSGYHPFPAMRRLSFLTG-----------DLFILVFSMDSRESFEEV 256

  Fly   321 KQILSRLQD-------------MDLLRHRPTILVANKIDLARSRA--------VSAQDGKCVACT 364
            .::...:.:             ...|...|.||..||.|......        ::.||..|.
  Fly   257 VRLRENILETKWAALNPGSGFKKKSLPKIPMILAGNKCDRDFKTVQVDEVMGYIAGQDNCCT--- 318

  Fly   365 FGAKFIEVSVGINHNCDELLAGTLTQIRLKKDQVQLQLNP------------------------- 404
                |:|.|...|:..|:|.....|...|     .|::.|
  Fly   319 ----FVECSARQNYRIDDLFHSLFTVSNL-----PLEMTPNHHRRLVSVFGAPSPLPPHGSAVGG 374

  Fly   405 -KKSKDKDKNKFKE-------NTNIETVETDNCLTDLKA---DDGGPRDANSPAHW 449
             ||:....|.:|.:       |....::.||..|...|.   ::|  ....||:.|
  Fly   375 TKKNALSIKRRFSDACGVVTPNARRPSIRTDLNLMRSKTMALNEG--EGVRSPSRW 428

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rgk3	NP_001286670.1	P-loop_NTPase	235..>396	CDD:422963	44/197 (22%)
CG8641	NP_001261494.1	Rhes_like	167..434	CDD:133343	59/288 (20%)
CG8641	NP_001261494.1	RAS	167..338	CDD:214541	42/189 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45453016
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0395
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.830