Protein Alignment Snoo and skilb

DIOPT Version :10

• Sequence 1: NP_609164.3
• Gene: Snoo / 5740414
• FlyBaseID: FBgn0085450
• Length: 1223
• Species: Drosophila melanogaster
• Sequence 2: NP_001124141.2
• Gene: skilb / 100170835
• ZFINID: ZDB-GENE-080723-40
• Length: 624
• Species: Danio rerio
• Alignment Length: 672
• Identity: 179/672 - (26%)
• Similarity: 257/672 - (38%)
• Gaps: 221/672 - (32%)

  Fly    52 GKCQASPPVVALIKKEI----------LSSPEPQDLHHHECSTRGTPPQIYSPATPPRELSQ--- 103
            ||.:|:|.:...:|..:          |..|.....||.:          |..|.|   |:|
Zfish    57 GKAEANPDLSPGLKHTLAQFSLSSQCSLGGPAAFTSHHGQ----------YKLAPP---LAQGGI 108

  Fly   104 ---PILSVADAGCGELYETKLEGKTIGCFSVGGEMRLCLPQFLNNVLNDFSLEQINRIFDELGIY 165
               |:|...|:.. :|....|||::|.|||||||:||||||.||.:|.||||:|||.:.|:|.:|
Zfish   109 AGGPLLVPPDSST-DLSMCSLEGESISCFSVGGELRLCLPQLLNTILRDFSLQQINSVCDQLYLY 172

  Fly   166 CSQCTHDQLVEFKAAKILPSDVKASGLITRTDAERLCAALLHRSDRNSYVPI-----ESLAKGAL 225
            ||:|...||...|...|||....:.||||.|||:|||..|||..:.    |:     |...:.:.
Zfish   173 CSRCDATQLHILKVLGILPPGTPSCGLITLTDAQRLCNTLLHPGEE----PLDREQEEKDGEESG 233

  Fly   226 SFHVYHKCFGKCEGICTPDMYSYQKPTCIKCLECDGWFSPQKFVGHVHRKFENHTCHWGFDSRNW 290
            .|.|.|:|.|||:|:..|.:||.....|::|.:|...|..::||.|.||:.:..||||||||..|
Zfish   234 GFWVEHQCLGKCQGLFVPQLYSSPDAPCVRCSQCRMLFCTERFVMHSHRQPDKRTCHWGFDSAKW 298

  Fly   291 HDYLHVA---LDVENREKYQIILDQLKEVELKEMHKAQRELEHKKR------------------- 333
            ..||.:|   |...:.||.|..|:.:|.       |.|:|    ||
Zfish   299 ACYLQLAQRHLGTADEEKLQQSLEDMKA-------KFQQE----KRQPHVGVSSPAFVFDSRLLA 352

  Fly   334 --KAEMLMDDGMLGS-------GPV-LGLAGH----PHGLVGALAPPPPPPMK------------ 372
              |.|...||.|..|       .|. .|||.|    |...:|:    |...|:
Zfish   353 GLKEEPSNDDLMWQSWYQYTHDKPAGNGLAQHSGCVPEKEIGS----PGTEMQTDTQDEKNQDAH 413

  Fly   373 --------------------------QPQMDIPSGKKQLQQLKGATVAASALEYQYQ------VM 405
                                      |...|.|..|:.::..|...|......|..|      .:
Zfish   414 NTDTKTLTFTGQEKSVQSDDGSADEWQRMADSPDCKRSVEHSKDNMVMELLQMYSAQHDKLQSTL 478

  Fly   406 YAHCVQKEREREREHLPHSHPLPR--QHRAVLVATTPYPHLPQYPTPPTLNSSSAFRPWGPDTTK 468
            |.   ||:.|:|.:.|.....|.|  .|..:....|.
Zfish   479 YR---QKQLEKELQALRQGETLDRCDLHGELEAVQTE---------------------------- 512

  Fly   469 AFLHAYGATLSSLPYACQEPPELQNPERVVRS----------TDKRYAERTYQPNVALAPRKSIL 523
               ||            |...|:|..:|.::|          ..|:.:..|:|..: .|.:.|.|
Zfish   513 ---HA------------QRLGEVQQEQRKLKSRLDQLRQQECRCKQLSTETHQETI-YARQLSEL 561

  Fly   524 SKERDK---DRERMEREVMERQRLREKETDHQVVHIKQERSQTPTPPTASPPDGVVLPLDVVEPP 585
            .:..|:   |||.::.|:...:..||: .:..:..:||:                     :.|..
Zfish   562 RQRLDRAEEDREELQDELRREREARER-LERTISELKQQ---------------------MREST 604

  Fly   586 HPSSSGS-NSPLPAHLPAAPAT 606
            ||:...| :||...|:  :||:
Zfish   605 HPAQHDSMDSPSDTHM--SPAS 624

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Snoo	NP_609164.3	DHD_Ski_Sno	116..206	CDD:410782	50/89 (56%)
		c-SKI_SMAD_bind	226..317	CDD:198114	38/93 (41%)
		AF-4	637..>789	CDD:461550
skilb	NP_001124141.2	None