DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Snoo and skila

DIOPT Version :10

Sequence 1:NP_609164.3 Gene:Snoo / 5740414 FlyBaseID:FBgn0085450 Length:1223 Species:Drosophila melanogaster
Sequence 2:XP_017207421.2 Gene:skila / 100007653 ZFINID:ZDB-GENE-070912-548 Length:728 Species:Danio rerio


Alignment Length:650 Identity:190/650 - (29%)
Similarity:267/650 - (41%) Gaps:177/650 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly    81 ECSTRGTPPQIYSPA------TPPRELSQPILSVADAGCGELYETKLEGKTIGCFSVGGEMRLCL 139
            ||:         |||      :||.....|:|...|:.. ||..:.|||::|.||.||||.||||
Zfish   123 ECA---------SPAGMAPLPSPPVLGGGPLLVPCDSST-ELTHSLLEGESISCFVVGGEKRLCL 177

  Fly   140 PQFLNNVLNDFSLEQINRIFDELGIYCSQCTHDQLVEFKAAKILPSDVKASGLITRTDAERLCAA 204
            ||.||:||.||||:|||.:.|||.:|||:|..:||...|...|||.:..:.||||.|||:|||.|
Zfish   178 PQVLNSVLRDFSLQQINAVCDELYVYCSRCHAEQLHILKVLGILPFNAPSCGLITLTDAQRLCNA 242

  Fly   205 LLH-----RSDRNSYVPIESLAKGA-LSFHVYHKCFGKCEGICTPDMYSYQKPTCIKCLECDGWF 263
            ||.     .:|.||.:|.:.|.|.: :||.|.|:|.|||:|:..|..|......||:|:||...|
Zfish   243 LLRPGATISADPNSKLPGQGLLKESDISFQVEHQCLGKCQGLFVPHFYVQPDAPCIQCMECQLLF 307

  Fly   264 SPQKFVGHVHRKFENHTCHWGFDSRNWHDYLHVALDVE-NREKYQI--ILDQLKEVELKEMHKAQ 325
            |||.||.|.|:..:..||||||||..|..||.:....| .:|:.|:  :||::||   |..::.:
Zfish   308 SPQNFVMHSHKSPDKRTCHWGFDSAKWPCYLQLGRKHEGTQEEPQLKQLLDEMKE---KFHYQLK 369

  Fly   326 RELEHKKRKAEMLMDDGMLGSGPVLGLAGHPHGLVGALAPPPPPPMKQPQMDIPSGKKQLQQLKG 390
            |.|:.|     ::.|||              ||...:.||.||.....     .||.::....||
Zfish   370 RPLDKK-----VVDDDG--------------HGRKSSPAPCPPNSKLS-----DSGLEEKLASKG 410

  Fly   391 AT----------------------VAASALEYQYQVMYAHCVQKEREREREH-----LPHSHPLP 428
            .:                      :..|...|.|..|.|..|...:|||..|     |...|...
Zfish   411 NSQSSLVFSRLFPDIKEEPGHAPIIHPSYYLYTYDKMVAPNVSLRKEREVSHEVLGALLKQHYSR 475

  Fly   429 RQHRAVLVATTPYPHLP-------------------QYPTPPTLNSSSAFRPWGP---------- 464
            |........||..|..|                   |.|.|..:.:|...:...|          
Zfish   476 RTFTHDNQPTTDLPASPSSTAEEAKSHHTGEAHERRQPPPPVAMETSPGGKQHAPISMAGKDSGA 540

  Fly   465 --DTTKAFLH----------------------------AYGATLSSLPYACQEPPELQN------ 493
              |..:..|.                            ..|...:.|.....|..||||      
Zfish   541 EDDKDRIMLEIVQMYRRQQEKLNSTLQKQLQLEMELEAVRGGEAARLRELSAEQLELQNELEAVH 605

  Fly   494 PERVVRSTDKRYAERTYQPNVALAPRKSILSKERDKD----------RERMEREVMERQRL---- 544
            .|...|..:.|..:|..:..:....::|...:.::::          |.|:||...|||.|    
Zfish   606 TEHAQRLGEVRQEQRQLEHRLEQLKQQSCACQPKEQEAQYNAQLCELRCRLERAEAERQELQEEL 670

  Fly   545 -REKET----DHQVVHIKQERSQTPTPPTASPPDGVVLPLDVVEPPHPSSSGSNSPLPAHLPAAP 604
             ||:|.    :..:..::|:.|::.:..:.||          .:||.||:    ||...|.|.:|
Zfish   671 CREREAREKLELMIAQLQQQMSRSASKGSNSP----------AQPPTPSA----SPQSQHSPCSP 721

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
SnooNP_609164.3 DHD_Ski_Sno 116..206 CDD:410782 52/89 (58%)
c-SKI_SMAD_bind 226..317 CDD:198114 42/93 (45%)
AF-4 637..>789 CDD:461550
skilaXP_017207421.2 None
Blue background indicates that the domain is not in the aligned region.

Return to query results.
Submit another query.