DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG34345 and CG31021

DIOPT Version :9

Sequence 1:	NP_001097101.1	Gene:	CG34345 / 5740402	FlyBaseID:	FBgn0085374	Length:	504	Species:	Drosophila melanogaster
Sequence 2:	NP_733392.2	Gene:	CG31021 / 43638	FlyBaseID:	FBgn0051021	Length:	453	Species:	Drosophila melanogaster

Alignment Length:	488	Identity:	117/488 - (23%)
Similarity:	216/488 - (44%)	Gaps:	79/488 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 IENSYMEHLNNYVSFLQQKIKTLRIFINSLTPNYLDHKVDRYKYVSNPLNSFGLLRRAHQDWPKL 114
            :|.:.::::.:|...|::||..:..::.....:..|...|..||:|||||||.|:|..||||...
  Fly     4 LERNLLQNMRDYAEKLEEKIDLINNYVEDYNVDIEDANEDPEKYLSNPLNSFRLIRHMHQDWVGW 68

  Fly   115 IAYLKDQGNIKVDIEEMNKLINRTPHANDMEEALMGMDRIEHFYDLKSSDMAQGLVAGQQLSS-- 177
            ..|::|....:. ::::..|:.:.|......:|...:..:..||..:.:|    |||..:.||
  Fly    69 QVYMEDLVAPEA-VQKVESLLPQLPQKEAFRKAARSVHSLTQFYGYEPAD----LVAKDERSSSL 128

  Fly   178 RMSASDCLALADYMYKRSEFRRAAEWYRIALSVFTKPKNNIAFK-FYAPK---RKELEKMFV--- 235
            .:|..||..|...:|:..::..||:|.::|...:|..::...|. ..||:   .::|.:..:
  Fly   129 HLSPLDCYHLGLELYEEQDYLGAAKWLQVAAHNYTLSRHRDLFNPLGAPRWQVYRDLGRTLLKLN 193

  Fly   236 ----------ISRLQEGSVENLTDCLKELSQ-------DPNNSLVHLRPRKSPTMIEQGCQGKFP 283
                      ..||...:|.    .:||..|       ||...::.|:|:  ||::|:.|:|:.|
  Fly   194 RQCAYDAYESALRLNSQNVH----LMKEAGQMELFSLRDPMEPILDLQPK--PTVLEKYCRGEVP 252

  Fly   284 PGP-QLVCRYNSTTTPFMRIAPLKEEEISRDPLIWLYHDVIYDSEIAQLTNV-------TREEMI 340
            ... :|.|..|.....|:..||:|.|::.:||.|.||...||:.||..:.|.       .|.|:.
  Fly   253 RHQGRLTCELNDWVHSFLAYAPIKFEDLQQDPFIILYPGSIYEQEIRHVENAYERCPPNDRFELK 317

  Fly   341 LGTTTNYTTPDRVNRLFHIKVTDDDGGKLDKTLVNRMADISGLDVGNTTTLARINYGLGGYFQEH 405
            ||             :....::|.....| |.:..|:.|::|:: ....|...:.|.....|:..
  Fly   318 LG-------------ISGCSISDGYSPVL-KRINERILDMAGVE-KTWDTFYIVEYAQLAPFEPF 367

  Fly   406 SDYMDIKLYPELTEEGDRLMTF-------LFYMTDVPVGGTTIFPGAQLAIQPKKGSALFWYNLH 463
            ..:.:...:|:|     .||.|       :.::.||.:||....|...:.:|||:|:.|..:...
  Fly   368 KLFRNSTKFPKL-----NLMNFEDVEAKVIIFLKDVTLGGAFTMPNGDILVQPKRGNVLITFENE 427

  Fly   464 NNGDPNLLTRHAVCPTIVGSRWVLVKSMLNYEQ 496
            .:..       .:||.|.|:..|::|.::..::
  Fly   428 EHST-------TICPIIEGTGLVMIKFIMKTDE 453

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34345	NP_001097101.1	P4Ha_N	40..170	CDD:285528	30/119 (25%)
CG34345	NP_001097101.1	P4Hc	324..489	CDD:214780	37/178 (21%)
CG31021	NP_733392.2	P4Ha_N	1..119	CDD:285528	30/119 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45452366
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1591
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	79	1.000	Inparanoid score	I2378
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10869
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.980