DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG34345 and CG9698

DIOPT Version :9

Sequence 1:	NP_001097101.1	Gene:	CG34345 / 5740402	FlyBaseID:	FBgn0085374	Length:	504	Species:	Drosophila melanogaster
Sequence 2:	NP_651806.2	Gene:	CG9698 / 43629	FlyBaseID:	FBgn0039784	Length:	547	Species:	Drosophila melanogaster

Alignment Length:	520	Identity:	146/520 - (28%)
Similarity:	245/520 - (47%)	Gaps:	62/520 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 VQEVIYSNSIRALSELREIENSYMEHLNNYVSFLQQKIKTLRIFINSLTPNYLDHKVDRYKYVSN 96
            |..|.:.:||..::::...|...:.|:..::|..|.|:..|:..:........:.:.....|..:
  Fly    20 VSGVEFFSSIHEMTKVFGYEQKMVLHMQKFLSDNQDKLDFLKARLREFENERNEAREWGPSYFES 84

  Fly    97 PLNSFGLLRRAHQDWPKLIAYLKDQGNIKVDIEEMNKLINR--TPHANDMEEALMGMDRIEHFYD 159
            |:|.:.|.:|...||.: :..|......:..:..:.|..||  .|...::|.|:.|:.|:::.|.
  Fly    85 PINKYLLNKRLTVDWQR-VENLMATSTGEKPLTRLRKFRNRETMPDKKELEGAIDGLLRLQYVYR 148

  Fly   160 LKSSDMAQGLVAGQQLSSRMSASDCLALADYMYKRSEFRRAAEWYRIALSVFT--------KPKN 216
            ||:.|:|:|::.|....:::::..|:.:|....:....|.|..|...|....|        ||:
  Fly   149 LKAKDLARGILDGVDYGTQLNSEHCVDIARLALRDQHPRLAHSWLIEANDRLTGGEKEEQLKPQ- 212

  Fly   217 NIAFKFYAPKRKELE----------KMFVISRLQEGSVENLTDCLKELSQDP--NNSLVHLRPRK 269
              ........:||||          ::..|....|...:|....|..||:..  |.|...|....
  Fly   213 --ILALLVQAKKELEDFRGLNDTYQELIGIQSASEEHAKNYETFLNALSEKALLNESKPILEHAP 275

  Fly   270 SPTMIEQG------------CQGKFPPGPQ----LVCRYNSTTTPFMRIAPLKEEEISRDPLIWL 318
            .|   |:|            |.|.:...|:    |.|.|.:.|.||:.|||||.||:.:|||:.|
  Fly   276 IP---EEGEPVGEFQAYSLTCSGHWRLTPKEQRHLRCGYVTETHPFLWIAPLKAEELFQDPLLVL 337

  Fly   319 YHDVIYDSEIAQLTNVTREEMILGTTTNY----TTPDRVNRLFHIKVTDDDGGKLDKTLVNRMAD 379
            ||||||.|||..:..:|...::..|.|::    .:..|.::...|.||   ..|:..|:..|:||
  Fly   338 YHDVIYQSEIDVIRKLTENRLMRATITSHNESVVSNVRTSQFTFIPVT---AHKVLSTIDQRVAD 399

  Fly   380 ISGLDVGNTTTLARINYGLGGYFQEHSDY-----MDIKLY--PELTEEGDRLMTFLFYMTDVPVG 437
            ::.|::.........|||:||::.:|.|:     .|..|.  ||:   |:|:.|.|||::||..|
  Fly   400 MTNLNMKYAEDHQFANYGIGGHYGQHMDWFYQTTFDAGLVSSPEM---GNRIATVLFYLSDVAQG 461

  Fly   438 GTTIFPGAQLAIQPKKGSALFWYNLHNNGDPNLLTRHAVCPTIVGSRWVLVKSMLNYEQMFKKPC 502
            |.|.||..:..::|||.:|.||:|||.:|..::.|:|..||.|.||:||..:.:...:|..::||
  Fly   462 GGTAFPQLRTLLKPKKYAAAFWHNLHASGVGDVRTQHGACPIIAGSKWVQNRWIRENDQSDRRPC 526

Fly 503 502
Fly 527 526

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34345	NP_001097101.1	P4Ha_N	40..170	CDD:285528	30/131 (23%)
CG34345	NP_001097101.1	P4Hc	324..489	CDD:214780	60/175 (34%)
CG9698	NP_651806.2	P4Ha_N	28..159	CDD:285528	30/131 (23%)
CG9698	NP_651806.2	P4Hc	345..516	CDD:214780	59/176 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45461856
Domainoid	1	1.000	91	0.514	Domainoid score	I2609
eggNOG	1	0.900	-	-		E1_KOG1591
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	79	1.000	Inparanoid score	I2378
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28396
OrthoDB	1	1.010	-	-		D192165at33208
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	1	1.000	-	-		mtm1209
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10869
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X129
	11	10.910