DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34345 and CG11828

DIOPT Version :9

Sequence 1:	NP_001097101.1	Gene:	CG34345 / 5740402	FlyBaseID:	FBgn0085374	Length:	504	Species:	Drosophila melanogaster
Sequence 2:	NP_651648.5	Gene:	CG11828 / 43416	FlyBaseID:	FBgn0039616	Length:	458	Species:	Drosophila melanogaster

Alignment Length:	493	Identity:	136/493 - (27%)
Similarity:	228/493 - (46%)	Gaps:	67/493 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 LSELREIENSYMEHLNNYVSFLQQKIKTLRIFINSLTPNYLDHKVDRYKYVSNPLNSFGLLRRAH 108
            ::.|.:||:..:.::..|...||.|:.|:|.|.............|...||:|||.||.|:||.:
  Fly     1 MASLLQIEDELIGYMRQYAMELQHKVNTMRTFQEEWMTRRALGPADPTSYVANPLISFPLMRRTY 65

  Fly   109 QDWPKLIAYLKD-------QGNIKVDIEEMNKLINRTPHANDMEEALMGMDRIEHFYDLKSSDMA 166
            .|.|||:...::       |..|..|:..::.:        ::|.|:.||.|.:..|.:..|:||
  Fly    66 TDVPKLLELAREEFKPGPFQKFIDYDLSSISDV--------ELETAVTGMLRFQGVYGMDESEMA 122

  Fly   167 QGLVAGQQLSSRMSASDCLALADYMYKRSEFRRAAEWYRIALSVFTK---PKNNI----AFKFYA 224
            .|.:.|:|.:|||||:||||:|.::....:.:.|.:|:::|:..:.:   |.|.:    ..:.|.
  Fly   123 NGKLHGKQYNSRMSAADCLAVATHLENVDKGKLACKWFKVAIDQYEEKLDPVNRLLQTGRSQIYE 187

  Fly   225 PKRKELEKMFVISRLQE--------GSVENLTDCLKELSQDPNNSLVHLRPRKSPTMIEQGCQGK 281
            .....|..|..:...|.        .|.|:.||..|.|.....:..||:          ..|:||
  Fly   188 KLGLTLLAMHDLPASQAAFRDSIGWASKEDNTDLAKHLKDKLAHMFVHV----------DNCRGK 242

  Fly   282 --FPPGPQLVCRYNSTTTPFMRIAPLKEEEISRDPLIWLYHDVIYDSEIAQLTNVT--------R 336
              .|....|.|||....:||:|:||:|.|:::.:|.:.|:||.|..:|...|.::|        :
  Fly   243 NLLPSKSYLRCRYLRDGSPFLRMAPVKLEQLNIEPFVGLFHDAISPAEQKDLLHLTDSRLEHRKK 307

  Fly   337 EEMILGTTTNYTTPDRVNRLFHIKVTDDDGGKLDKTLVNRMADISGLDVGNTTTLARINYGLGGY 401
            :...:....:....|.|.|:.                 .|:.||:|.|:..:..|...|||:||.
  Fly   308 DSSSVEAKVDTNASDHVRRIH-----------------QRIEDITGFDLEESEPLTVSNYGIGGQ 355

  Fly   402 FQEHSDYMDIKLYPELTEEGDRLMTFLFYMTDVPVGGTTIFPGAQLAIQPKKGSALFWYNLHNNG 466
            ...|.|....|.:.....:..|..:.:||::||.:||...||......:|::||||.|:|..|:|
  Fly   356 DFIHLDCEQPKEFIGYYPKEYRSASAMFYLSDVQMGGYASFPDLGFGFKPRRGSALVWHNTDNSG 420

  Fly   467 DPNLLTRHAVCPTIVGSRWVLVKSMLNYEQMFKKPCYK 504
            :.:..:..|.||.::|::||..|.:....|..:|.|.|
  Fly   421 NCDTRSLQATCPVLLGNQWVAKKWISGSGQWRRKSCRK 458

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34345	NP_001097101.1	P4Ha_N	40..170	CDD:285528	38/132 (29%)
CG34345	NP_001097101.1	P4Hc	324..489	CDD:214780	44/172 (26%)
CG11828	NP_651648.5	P4Ha_N	1..126	CDD:285528	38/132 (29%)
CG11828	NP_651648.5	P4Hc	287..445	CDD:214780	45/174 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45461839
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1591
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	79	1.000	Inparanoid score	I2378
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D192165at33208
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	1	1.000	-	-		mtm1209
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10869
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X129
	9	8.900