Protein Alignment CG34162 and SLC8B1

DIOPT Version :10

• Sequence 1: NP_001097149.2
• Gene: CG34162 / 5740392
• FlyBaseID: FBgn0085191
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: NP_079235.2
• Gene: SLC8B1 / 80024
• HGNCID: 26175
• Length: 584
• Species: Homo sapiens
• Alignment Length: 613
• Identity: 131/613 - (21%)
• Similarity: 229/613 - (37%)
• Gaps: 165/613 - (26%)

  Fly     7 SAVNR---------CSLPRESFRNANQTCGLARSTLSCGSLVYLINYLDICFCVFK---LP---T 56
            |.||:         |.|      |.:..|...|:...|.|....::||:..||.|.   ||   |
Human    43 SGVNQTPVVDCRKVCGL------NVSDRCDFIRTNPDCHSDGGYLDYLEGIFCHFPPSLLPLAVT 101

  Fly    57 MSIYGLISAFLLMVHLSVLFMVTKYFFVPNLATLIEFAPMT--MFGSSFLLFG---PTFFVSYYN 116
            :.:..|:..||      :|.:....||.|||:.:.....::  :.|.:||.||   |..|    :
Human   102 LYVSWLLYLFL------ILGVTAAKFFCPNLSAISTTLKLSHNVAGVTFLAFGNGAPDIF----S 156

  Fly   117 SFWEICNPRKPESICLSPLQFAKIMGDILRYIVIGFMVICAQGYRVDGITFWSCLSFILTGMVYL 181
            :.....:|. ...:.|..|..|   |.::..:|.|            |||...  .|:.....:.
Human   157 ALVAFSDPH-TAGLALGALFGA---GVLVTTVVAG------------GITILH--PFMAASRPFF 203

  Fly   182 YIVIKKSYNVYLIVADLYSIKFRVTVF-------LYTFLMVLLVIFVVSYANFQR---------- 229
            ..::  .|.|.:.:..|...:.|||:.       ||.|.:|.:::....|...:|
Human   204 RDIV--FYMVAVFLTFLMLFRGRVTLAWALGYLGLYVFYVVTVILCTWIYQRQRRGSLFCPMPVT 266

  Fly   230 ----SKVKSKQTQENFLEMDSGDEI--LGKYQK--------------QMEFSRREIWLKAVNGYR 274
                |..:..:...|....|.|||.  |..||:              .|::.|:..:.||:
Human   267 PEILSDSEEDRVSSNTNSYDYGDEYRPLFFYQETTAQILVRALNPLDYMKWRRKSAYWKAL---- 327

  Fly   275 NMADSNVIYRIAMIPSYFVLANFIPVISNDRALIGWNKYTSCLGLFFLPIICL------PHGFKA 333
                     ::..:|..|:|...:||:..|:....|.:..:||.|...|::.:      .:|...
Human   328 ---------KVFKLPVEFLLLLTVPVVDPDKDDQNWKRPLNCLHLVISPLVVVLTLQSGTYGVYE 383

  Fly   334 VS-----WLIMFLTCWTLSILTFISTHSLRRPNNIWIFALLGLIVSSVFINLLSREIENIIYQYI 393
            :.     |:::.:....|:.:||.:|...:.|...|:||.||.:.|:::||..:.|:.||: :.:
Human   384 IGGLVPVWVVVVIAGTALASVTFFATSDSQPPRLHWLFAFLGFLTSALWINAAATEVVNIL-RSL 447

  Fly   394 SMQFDVMPDVTALVYF----GLGEMLSESIVVRCLQQRKMWDATFGVVMSLVTYAIFLAFPLLFF 454
            .:.|.:...|..|...    .:|:..|:..:.|....|..:.|.||.::..:...:.|.
Human   448 GVVFRLSNTVLGLTLLAWGNSIGDAFSDFTLARQGYPRMAFSACFGGIIFNILVGVGLG------ 506

  Fly   455 QGCYNNKCSIMVT-SSTETTIH----------------FIFLVLSTCLLHVSLSG-YEFRISLLF 501
                   |.:.:: |.||..:.                .:|.::|..|....||. |.|.: |||
Human   507 -------CLLQISRSHTEVKLEPDGLLVWVLAGALGLSLVFSLVSVPLQCFQLSRVYGFCL-LLF 563

  Fly   502 YLLVLTVFYVTLQWMTHYDWILSFATLH 529
            ||..|.|..:|           .|..:|
Human   564 YLNFLVVALLT-----------EFGVIH 580

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG34162	NP_001097149.2	None
SLC8B1	NP_079235.2	PLN03151	63..584	CDD:215604	125/587 (21%)